Gene description for Sept9
Gene name septin 9
Gene symbol Sept9
Other names/aliases Eseptin
Msf
Slpa
Species Rattus norvegicus
 Database cross references - Sept9
ExoCarta ExoCarta_83788
Vesiclepedia VP_83788
Entrez Gene 83788
UniProt Q9QZR6  
 Sept9 identified in sEVs derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Sept9
Molecular Function
    GTPase activity GO:0003924 IBA
    GTP binding GO:0005525 IEA
    molecular adaptor activity GO:0060090 IBA
Biological Process
    protein localization GO:0008104 IBA
    biological_process GO:0008150 ND
    cytoskeleton-dependent cytokinesis GO:0061640 IBA
    anterograde dendritic transport of neurotransmitter receptor complex GO:0098971 IDA
    anterograde dendritic transport of neurotransmitter receptor complex GO:0098971 IMP
    anterograde dendritic transport of neurotransmitter receptor complex GO:0098971 NAS
    positive regulation of non-motile cilium assembly GO:1902857 IEA
    positive regulation of non-motile cilium assembly GO:1902857 ISO
Subcellular Localization
    stress fiber GO:0001725 IEA
    stress fiber GO:0001725 ISO
    cytoplasm GO:0005737 IEA
    microtubule GO:0005874 IEA
    microtubule GO:0005874 ISO
    axoneme GO:0005930 IEA
    axoneme GO:0005930 ISO
    septin ring GO:0005940 IBA
    actin cytoskeleton GO:0015629 ISO
    microtubule cytoskeleton GO:0015630 IBA
    septin complex GO:0031105 IBA
    septin complex GO:0031105 IEA
    septin complex GO:0031105 ISO
    septin complex GO:0031105 ISS
    cell division site GO:0032153 IBA
    dendrite cytoplasm GO:0032839 IEA
    perinuclear region of cytoplasm GO:0048471 IEA
    perinuclear region of cytoplasm GO:0048471 ISO
    non-motile cilium GO:0097730 IEA
    non-motile cilium GO:0097730 ISO
    presynapse GO:0098793 IDA
 Experiment description of studies that identified Sept9 in sEVs
1
Experiment ID 96
MISEV standards
EM
Biophysical techniques
TSG101|HSP90|HSC70|MHCI
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E."
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D2 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Sept9
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Sept9 is involved
No pathways found





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