Gene description for Smarcd2
Gene name SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
Gene symbol Smarcd2
Other names/aliases AW322457
Baf60b
Species Mus musculus
 Database cross references - Smarcd2
ExoCarta ExoCarta_83796
Vesiclepedia VP_83796
Entrez Gene 83796
UniProt Q99JR8  
 Smarcd2 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Smarcd2
Molecular Function
    transcription coregulator activity GO:0003712 IBA
Biological Process
    nucleosome disassembly GO:0006337 IEA
    nucleosome disassembly GO:0006337 ISO
    chromatin remodeling GO:0006338 ISO
    chromatin remodeling GO:0006338 NAS
    regulation of transcription by RNA polymerase II GO:0006357 IBA
    regulation of transcription by RNA polymerase II GO:0006357 NAS
    regulation of mitotic metaphase/anaphase transition GO:0030071 NAS
    positive regulation of T cell differentiation GO:0045582 NAS
    positive regulation of cell differentiation GO:0045597 NAS
    positive regulation of myoblast differentiation GO:0045663 NAS
    regulation of G0 to G1 transition GO:0070316 NAS
    regulation of G1/S transition of mitotic cell cycle GO:2000045 NAS
    positive regulation of double-strand break repair GO:2000781 NAS
    regulation of nucleotide-excision repair GO:2000819 NAS
Subcellular Localization
    kinetochore GO:0000776 NAS
    chromatin GO:0000785 NAS
    nucleus GO:0005634 IBA
    nucleoplasm GO:0005654 ISO
    nucleoplasm GO:0005654 TAS
    nuclear matrix GO:0016363 NAS
    SWI/SNF complex GO:0016514 IBA
    SWI/SNF complex GO:0016514 ISO
    SWI/SNF complex GO:0016514 NAS
    RSC-type complex GO:0016586 NAS
    brahma complex GO:0035060 NAS
    SWI/SNF superfamily-type complex GO:0070603 IDA
    bBAF complex GO:0140092 NAS
 Experiment description of studies that identified Smarcd2 in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Smarcd2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Fitm2  
Negative Genetic Mus musculus
2 Cebpa  
Affinity Capture-MS Mus musculus
3 Smarca4  
Affinity Capture-Western Mus musculus
4 Tfcp2l1  
Affinity Capture-MS Mus musculus
5 Mecp2  
Affinity Capture-MS Mus musculus
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here