Gene description for Smarcd2
Gene name SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
Gene symbol Smarcd2
Other names/aliases AW322457
Baf60b
Species Mus musculus
 Database cross references - Smarcd2
ExoCarta ExoCarta_83796
Entrez Gene 83796
UniProt Q99JR8  
 Smarcd2 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Smarcd2
Molecular Function
    RNA polymerase II distal enhancer sequence-specific DNA binding GO:0000980 ISO
    RNA polymerase II core promoter proximal region sequence-specific DNA binding GO:0000978 ISO
    nucleosomal DNA binding GO:0031492 ISO
Biological Process
    regulation of transcription, DNA-templated GO:0006355 IEA
    chromatin modification GO:0016568 IEA
    ATP-dependent chromatin remodeling GO:0043044 ISO
    chromatin remodeling GO:0006338 ISO
    nucleosome disassembly GO:0006337 ISO
    transcription, DNA-templated GO:0006351 IEA
Subcellular Localization
    nuclear chromatin GO:0000790 ISO
    nucleus GO:0005634 ISO
    BAF-type complex GO:0090544 IDA
    SWI/SNF complex GO:0016514 ISO
    protein complex GO:0043234 ISO
 Experiment description of studies that identified Smarcd2 in exosomes
1
Experiment ID 15
ISEV standards
✔
EM
EV Biophysical techniques
✘ EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Smarcd2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Smarcd2 is involved
PathwayEvidenceSource
RMTs methylate histone arginines IEA Reactome





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