Gene description for Pon1
Gene name	paraoxonase 1
Gene symbol	Pon1
Other names/aliases	-
Species	Rattus norvegicus
Database cross references - Pon1
ExoCarta	ExoCarta_84024
Vesiclepedia	VP_84024
Entrez Gene	84024
UniProt	P55159
Pon1 identified in sEVs derived from the following tissue/cell type
Hepatocytes	19367702

Gene ontology annotations for Pon1

Molecular Function     aryldialkylphosphatase activity GO:0004063 IBA     aryldialkylphosphatase activity GO:0004063 IDA     aryldialkylphosphatase activity GO:0004063 IEA     aryldialkylphosphatase activity GO:0004063 ISO     aryldialkylphosphatase activity GO:0004063 ISS     arylesterase activity GO:0004064 IBA     arylesterase activity GO:0004064 IEA     arylesterase activity GO:0004064 ISO     arylesterase activity GO:0004064 ISS     calcium ion binding GO:0005509 IEA     calcium ion binding GO:0005509 ISO     calcium ion binding GO:0005509 ISS     phospholipid binding GO:0005543 IEA     phospholipid binding GO:0005543 ISO     protein homodimerization activity GO:0042803 IEA     protein homodimerization activity GO:0042803 ISO     metal ion binding GO:0046872 IEA     acyl-L-homoserine-lactone lactonohydrolase activity GO:0102007 IEA     acyl-L-homoserine-lactone lactonohydrolase activity GO:0102007 ISO Biological Process     cholesterol metabolic process GO:0008203 IEA     cholesterol metabolic process GO:0008203 ISO     response to xenobiotic stimulus GO:0009410 IEP     response to toxic substance GO:0009636 IBA     response to toxic substance GO:0009636 IEA     response to toxic substance GO:0009636 ISO     response to toxic substance GO:0009636 ISO     positive regulation of cholesterol efflux GO:0010875 IEA     positive regulation of cholesterol efflux GO:0010875 ISO     response to nutrient levels GO:0031667 IEP     response to lipopolysaccharide GO:0032496 IEP     negative regulation of plasma lipoprotein oxidation GO:0034445 ISO     carboxylic acid catabolic process GO:0046395 IEA     carboxylic acid catabolic process GO:0046395 ISO     organophosphate catabolic process GO:0046434 IEA     organophosphate catabolic process GO:0046434 ISO     phosphatidylcholine metabolic process GO:0046470 IEA     phosphatidylcholine metabolic process GO:0046470 ISO     response to fatty acid GO:0070542 IEP     lactone catabolic process GO:1901335 IEA     lactone catabolic process GO:1901335 ISO     response to fluoride GO:1902617 IDA Subcellular Localization     extracellular region GO:0005576 IEA     extracellular space GO:0005615 IBA     extracellular space GO:0005615 IDA     extracellular space GO:0005615 ISO     high-density lipoprotein particle GO:0034364 ISO     spherical high-density lipoprotein particle GO:0034366 IEA     spherical high-density lipoprotein particle GO:0034366 ISO