Gene description for Fmo3
Gene name flavin containing monooxygenase 3
Gene symbol Fmo3
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Fmo3
ExoCarta ExoCarta_84493
Vesiclepedia VP_84493
Entrez Gene 84493
UniProt Q9EQ76  
 Fmo3 identified in sEVs derived from the following tissue/cell type
Hepatocytes 19367702    
 Gene ontology annotations for Fmo3
Molecular Function
    monooxygenase activity GO:0004497 TAS
    N,N-dimethylaniline monooxygenase activity GO:0004499 IBA
    N,N-dimethylaniline monooxygenase activity GO:0004499 IDA
    N,N-dimethylaniline monooxygenase activity GO:0004499 IEA
    amino acid binding GO:0016597 IPI
    trimethylamine monooxygenase activity GO:0034899 IEA
    albendazole monooxygenase activity GO:0047638 IEA
    hypotaurine monooxygenase activity GO:0047822 IEA
    hypotaurine monooxygenase activity GO:0047822 ISO
    flavin adenine dinucleotide binding GO:0050660 IEA
    NADP binding GO:0050661 IEA
    NADP binding GO:0050661 IPI
Biological Process
    xenobiotic metabolic process GO:0006805 IDA
    taurine biosynthetic process GO:0042412 IEA
    taurine biosynthetic process GO:0042412 ISO
Subcellular Localization
    endoplasmic reticulum membrane GO:0005789 IEA
 Experiment description of studies that identified Fmo3 in sEVs
1
Experiment ID 35
MISEV standards
CEM
Biophysical techniques
TSG101|Alix|CD81|CD63
Enriched markers
HSPA5
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19367702    
Organism Rattus norvegicus
Experiment description Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes.
Authors "Conde-Vancells J, Rodriguez-Suarez E, Embade N, Gil D, Matthiesen R, Valle M, Elortza F, Lu SC, Mato JM, Falcon-Perez JM"
Journal name JPR
Publication year 2008
Sample Hepatocytes
Sample name Hepatocytes
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
 Protein-protein interactions for Fmo3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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