Gene description for Fmo3
Gene name flavin containing monooxygenase 3
Gene symbol Fmo3
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Fmo3
ExoCarta ExoCarta_84493
Entrez Gene 84493
UniProt Q9EQ76  
 Fmo3 identified in exosomes derived from the following tissue/cell type
Hepatocytes 19367702    
 Gene ontology annotations for Fmo3
Molecular Function
    flavin adenine dinucleotide binding GO:0050660 IEA
    amino acid binding GO:0016597 IPI
    N,N-dimethylaniline monooxygenase activity GO:0004499 IDA
    NADP binding GO:0050661 IPI
    monooxygenase activity GO:0004497 TAS
    trimethylamine monooxygenase activity GO:0034899 IEA
Biological Process
    oxidation-reduction process GO:0055114 IBA
    drug metabolic process GO:0017144 IDA
Subcellular Localization
    integral component of membrane GO:0016021 IEA
    intracellular membrane-bounded organelle GO:0043231 IDA
    endoplasmic reticulum membrane GO:0005789 IEA
 Experiment description of studies that identified Fmo3 in exosomes
1
Experiment ID 35
ISEV standards
✔
CEM
EV Biophysical techniques
✔
TSG101|Alix
EV Cytosolic markers
✔
CD81|CD63
EV Membrane markers
✔
HSPA5
EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19367702    
Organism Rattus norvegicus
Experiment description Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes.
Authors Conde-Vancells J, Rodriguez-Suarez E, Embade N, Gil D, Matthiesen R, Valle M, Elortza F, Lu SC, Mato JM, Falcon-Perez JM
Journal name JPR
Publication year 2008
Sample Hepatocytes
Sample name Hepatocytes
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
 Protein-protein interactions for Fmo3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Fmo3 is involved
PathwayEvidenceSource
FMO oxidises nucleophiles IEA Reactome





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