Gene description for Ptp4a2
Gene name protein tyrosine phosphatase type IVA, member 2
Gene symbol Ptp4a2
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Ptp4a2
ExoCarta ExoCarta_85237
Entrez Gene 85237
UniProt Q6P9X4  
 Ptp4a2 identified in exosomes derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Ptp4a2
Molecular Function
    protein tyrosine phosphatase activity GO:0004725 IEA
Biological Process
    peptidyl-tyrosine dephosphorylation GO:0035335 IEA
Subcellular Localization
    extracellular exosome GO:0070062 ISO
    cytoplasm GO:0005737 ISO
    plasma membrane GO:0005886 IEA
    early endosome GO:0005769 IEA
 Experiment description of studies that identified Ptp4a2 in exosomes
1
Experiment ID 90
ISEV standards
EM
EV Biophysical techniques
HSC70|HSP90|TSG101
EV Cytosolic markers
MHCI
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D2 Rep 1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Ptp4a2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Ptp4a2 is involved
No pathways found





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