Gene description for S100a6
Gene name S100 calcium binding protein A6
Gene symbol S100a6
Other names/aliases -
Species Rattus norvegicus
 Database cross references - S100a6
ExoCarta ExoCarta_85247
Vesiclepedia VP_85247
Entrez Gene 85247
UniProt P05964  
 S100a6 identified in sEVs derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for S100a6
Molecular Function
    calcium ion binding GO:0005509 IBA
    calcium ion binding GO:0005509 IDA
    calcium ion binding GO:0005509 ISO
    calcium ion binding GO:0005509 ISS
    tropomyosin binding GO:0005523 ISO
    zinc ion binding GO:0008270 ISO
    monoatomic ion transmembrane transporter activity GO:0015075 IDA
    protein homodimerization activity GO:0042803 ISO
    S100 protein binding GO:0044548 IBA
    S100 protein binding GO:0044548 ISO
    calcium-dependent protein binding GO:0048306 IBA
    calcium-dependent protein binding GO:0048306 ISO
Biological Process
    monoatomic ion transmembrane transport GO:0034220 IEA
    cellular response to virus GO:0098586 ISO
Subcellular Localization
    ruffle GO:0001726 ISO
    nucleus GO:0005634 IBA
    nucleus GO:0005634 ISO
    nuclear envelope GO:0005635 ISO
    cytoplasm GO:0005737 ISO
    cytosol GO:0005829 ISO
    cytosol GO:0005829 ISS
    plasma membrane GO:0005886 ISO
    cytoplasmic side of plasma membrane GO:0009898 ISO
    cytoplasmic side of plasma membrane GO:0009898 ISS
    perinuclear region of cytoplasm GO:0048471 IBA
    perinuclear region of cytoplasm GO:0048471 ISO
 Experiment description of studies that identified S100a6 in sEVs
1
Experiment ID 225
MISEV standards
✔
EM
Biophysical techniques
✔
GAPDH|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors "Lee JE, Moon PG, Lee IK, Baek MC"
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for S100a6
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which S100a6 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here