Gene description for RPPH1
Gene name ribonuclease P RNA component H1
Gene symbol RPPH1
Other names/aliases H1RNA
RPPH1-1
Species Homo sapiens
 Database cross references - RPPH1
ExoCarta ExoCarta_85495
Vesiclepedia VP_85495
Entrez Gene 85495
HGNC 19273
MIM 608513
 RPPH1 identified in sEVs derived from the following tissue/cell type
Endothelial cells 26027894    
 Gene ontology annotations for RPPH1
Molecular Function
    ribonuclease P activity GO:0004526 IEA
Biological Process
    tRNA processing GO:0008033 IEA
Subcellular Localization
    ribonuclease P complex GO:0030677 IEA
 Experiment description of studies that identified RPPH1 in sEVs
1
Experiment ID 226
MISEV standards
EM
Biophysical techniques
GAPDH|CD9|FLOT1
Enriched markers
LMNA|H2AFX|ATP5A1|TOMM20
Negative markers
Particle analysis
Identified molecule mRNA
Identification method Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
PubMed ID 26027894    
Organism Homo sapiens
Experiment description "Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting"
Authors "Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar"
Journal name Journal of Extracellular Vesicles
Publication year 2015
Sample Endothelial cells
Sample name HMEC-1
Isolation/purification methods Differential ultracentrifugation
Sucrose density gradient
Flotation density 1.10 g/mL
Molecules identified in the study miRNA
Protein
snoRNA
lncRNA
yRNA
snRNA
mRNA
ncRNA
mtRNA
vtRNA
scaRNA
lincRNA
Methods used in the study Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
Western blotting
 Protein-protein interactions for RPPH1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which RPPH1 is involved
No pathways found





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