Gene description for SEMA5A
Gene name	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
Gene symbol	SEMA5A
Other names/aliases	SEMAF semF
Species	Homo sapiens
Database cross references - SEMA5A
ExoCarta	ExoCarta_9037
Entrez Gene	9037
HGNC	10736
MIM	609297
UniProt	Q13591
SEMA5A identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells	Unpublished / Not applicable

Gene ontology annotations for SEMA5A

Molecular Function     semaphorin receptor binding GO:0030215 ISS     syndecan binding GO:0045545 ISS     chondroitin sulfate proteoglycan binding GO:0035373 ISS     heparan sulfate proteoglycan binding GO:0043395 ISS     axon guidance receptor activity GO:0008046 IEA Biological Process     positive regulation of axon extension involved in axon guidance GO:0048842 ISS     positive regulation of endothelial cell chemotaxis GO:2001028 ISS     positive regulation of angiogenesis GO:0045766 ISS     signal clustering GO:1990256 ISS     cell chemotaxis GO:0060326 ISS     positive regulation of endothelial cell proliferation GO:0001938 ISS     cell-cell signaling GO:0007267 TAS     nervous system development GO:0007399 TAS     diencephalon development GO:0021536 ISS     cell adhesion GO:0007155 TAS     positive regulation of catenin import into nucleus GO:0035413 ISS     axon guidance GO:0007411 TAS     positive regulation of actin filament depolymerization GO:0030836 ISS     negative regulation of axon extension involved in axon guidance GO:0048843 ISS     axonal fasciculation GO:0007413 ISS     patterning of blood vessels GO:0001569 IEA     blood vessel endothelial cell proliferation involved in sprouting angiogenesis GO:0002043 ISS     positive regulation of protein kinase B signaling GO:0051897 ISS     negative regulation of cell adhesion GO:0007162 ISS     positive chemotaxis GO:0050918 ISS     negative regulation of endothelial cell apoptotic process GO:2000352 ISS Subcellular Localization     extracellular exosome GO:0070062 IDA     integral component of membrane GO:0016021 IEA     membrane GO:0016020 ISS     plasma membrane GO:0005886 TAS