Gene description for SEMA5A
Gene name	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
Gene symbol	SEMA5A
Other names/aliases	SEMAF semF
Species	Homo sapiens
Database cross references - SEMA5A
ExoCarta	ExoCarta_9037
Vesiclepedia	VP_9037
Entrez Gene	9037
HGNC	10736
MIM	609297
UniProt	Q13591
SEMA5A identified in sEVs derived from the following tissue/cell type
Mesenchymal stem cells	Unpublished / Not applicable

Gene ontology annotations for SEMA5A

Molecular Function     semaphorin receptor binding GO:0030215 IBA     semaphorin receptor binding GO:0030215 ISS     chondroitin sulfate proteoglycan binding GO:0035373 ISS     heparan sulfate proteoglycan binding GO:0043395 ISS     chemorepellent activity GO:0045499 IBA     syndecan binding GO:0045545 ISS Biological Process     neural crest cell migration GO:0001755 IBA     positive regulation of endothelial cell proliferation GO:0001938 ISS     blood vessel endothelial cell proliferation involved in sprouting angiogenesis GO:0002043 ISS     cell adhesion GO:0007155 TAS     negative regulation of cell adhesion GO:0007162 ISS     cell-cell signaling GO:0007267 TAS     nervous system development GO:0007399 TAS     axon guidance GO:0007411 IBA     axonal fasciculation GO:0007413 ISS     diencephalon development GO:0021536 ISS     positive regulation of cell migration GO:0030335 IBA     positive regulation of actin filament depolymerization GO:0030836 ISS     positive regulation of angiogenesis GO:0045766 ISS     axon extension GO:0048675 IBA     positive regulation of axon extension involved in axon guidance GO:0048842 ISS     negative regulation of axon extension involved in axon guidance GO:0048843 ISS     positive chemotaxis GO:0050918 ISS     negative chemotaxis GO:0050919 IEA     positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction GO:0051897 ISS     cell chemotaxis GO:0060326 ISS     semaphorin-plexin signaling pathway GO:0071526 IBA     positive regulation of canonical Wnt signaling pathway GO:0090263 ISS     signal clustering GO:1990256 ISS     negative regulation of endothelial cell apoptotic process GO:2000352 ISS     positive regulation of endothelial cell chemotaxis GO:2001028 ISS Subcellular Localization     plasma membrane GO:0005886 IBA     plasma membrane GO:0005886 TAS     membrane GO:0016020 ISS     extracellular exosome GO:0070062 HDA