Gene description for CD1C
Gene name CD1c molecule
Gene symbol CD1C
Other names/aliases BDCA1
CD1
CD1A
R7
Species Homo sapiens
 Database cross references - CD1C
ExoCarta ExoCarta_911
Entrez Gene 911
HGNC 1636
MIM 188340
UniProt P29017  
 CD1C identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for CD1C
Molecular Function
    endogenous lipid antigen binding GO:0030883 IDA
    beta-2-microglobulin binding GO:0030881 IBA
    glycolipid binding GO:0051861 IDA
    lipopeptide binding GO:0071723 IDA
    exogenous lipid antigen binding GO:0030884 IDA
Biological Process
    T cell activation involved in immune response GO:0002286 IDA
    antigen processing and presentation, exogenous lipid antigen via MHC class Ib GO:0048007 IBA
Subcellular Localization
    plasma membrane GO:0005886 TAS
    endosome membrane GO:0010008 IEA
    integral component of plasma membrane GO:0005887 TAS
 Experiment description of studies that identified CD1C in exosomes
1
Experiment ID 217
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
CD81|CD9|CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for CD1C
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which CD1C is involved
No pathways found





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