Gene ontology annotations for KRT75
Experiment description of studies that identified KRT75 in exosomes
1
Experiment ID
489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Rattus norvegicus
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Bone marrow mesenchymal stem cells
Sample name
BMSC - Passage 6
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
2
Experiment ID
490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Rattus norvegicus
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Bone marrow mesenchymal stem cells
Sample name
BMSC - Passage 7
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
3
Experiment ID
491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Rattus norvegicus
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Bone marrow mesenchymal stem cells
Sample name
BMSC - Passage 8
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
4
Experiment ID
492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Rattus norvegicus
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Bone marrow mesenchymal stem cells
Sample name
BMSC - Passage 9
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
5
Experiment ID
494
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD151|CD63|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
✘
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
35931686
Organism
Homo sapiens
Experiment description
Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors
"Varela-EirÃÂn M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, GarcÃÂa-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name
Cell Death Dis
Publication year
2022
Sample
Chondrocytes
Sample name
Osteoarthritic cartilage
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
6
Experiment ID
496
MISEV standards
✘
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
✘
Negative markers
✘
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
35931686
Organism
Homo sapiens
Experiment description
Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors
"Varela-EirÃÂn M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, GarcÃÂa-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name
Cell Death Dis
Publication year
2022
Sample
Chondrocytes
Sample name
Healthy cartilage
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
7
Experiment ID
20
MISEV standards
✔
EM
Biophysical techniques
✔
HSP90|CD63|CD81|LAMP1
Enriched markers
✔
GOLGA2|cytochrome c
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
17956143
Organism
Homo sapiens
Experiment description
Proteomic analysis of microvesicles derived from human colorectal cancer cells.
Authors
"Choi DS, Lee JM, Park GW, Lim HW, Bang JY, Kim YK, Kwon KH, Kwon HJ, Kim KP, Gho YS"
Journal name
JPR
Publication year
2007
Sample
Colorectal cancer cells
Sample name
HT29
Isolation/purification methods
Differential centrifugation Sucrose density gradient Diafiltration
Flotation density
1.16 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry [LTQ] Western blotting
8
Experiment ID
21
MISEV standards
✔
EM|IEM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD63
Enriched markers
✘
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
PubMed ID
19837982
Organism
Homo sapiens
Experiment description
Proteomic and bioinformatic analysis of immunoaffinity-purified exosomes derived from the human colon tumor cell line LIM1215.
Authors
"Suresh Mathivanan, Justin W.E. Lim, Bow J. Tauro, Hong Ji, Robert L. Moritz and Richard J. Simpson"
Journal name
MCP
Publication year
2009
Sample
Colorectal cancer cells
Sample name
LIM1215
Isolation/purification methods
Filtration Ultracentrifugation Sucrose density gradient
Flotation density
1.10-1.12 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry [Orbitrap] Western blotting
9
Experiment ID
224
MISEV standards
✔
EM|AFM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81
Enriched markers
✔
GOLGA2
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
25944692
Organism
Homo sapiens
Experiment description
Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors
"Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name
Oncotarget
Publication year
2015
Sample
Neuroblastoma cells
Sample name
SH-SY5Y
Isolation/purification methods
Differential centrifugation Ultracentrifugation OptiPrep density gradient
Flotation density
1.10 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry Western blotting
10
Experiment ID
146
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|CD9
Enriched markers
✔
HSP90B1
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
PubMed ID
22723089
Organism
Homo sapiens
Experiment description
Prostate cancer cell derived exosomes
Authors
"Hosseini-Beheshti E, Guns ES."
Journal name
MCP
Publication year
2012
Sample
Prostate cancer cells
Sample name
RWPE - Rep 2
Isolation/purification methods
Sucrose density gradient
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry [QTOF]
11
Experiment ID
834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
35333565
Organism
Homo sapiens
Experiment description
LAMP2A regulates the loading of proteins into exosomes
Authors
"Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name
Sci Adv
Publication year
2022
Sample
Retinal pigment epithelial cells
Sample name
ARPE-19
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
12
Experiment ID
835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
35333565
Organism
Homo sapiens
Experiment description
LAMP2A regulates the loading of proteins into exosomes
Authors
"Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name
Sci Adv
Publication year
2022
Sample
Retinal pigment epithelial cells
Sample name
ARPE-19
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
Protein-protein interactions for KRT75
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
KRT76
51350
Two-hybrid
Homo sapiens
Cross-Linking-MS (XL-MS)
Homo sapiens
2
KRT77
374454
Cross-Linking-MS (XL-MS)
Homo sapiens
3
SUFU
51684
Two-hybrid
Homo sapiens
4
KRT37
8688
Two-hybrid
Homo sapiens
5
KRT73
319101
Cross-Linking-MS (XL-MS)
Homo sapiens
6
EPM2AIP1
9852
Two-hybrid
Homo sapiens
7
LGR4
55366
Affinity Capture-MS
Homo sapiens
8
TRIML2
Two-hybrid
Homo sapiens
9
CPNE7
27132
Two-hybrid
Homo sapiens
10
KIFC3
3801
Two-hybrid
Homo sapiens
11
SCNM1
Two-hybrid
Homo sapiens
12
KRT17
3872
Cross-Linking-MS (XL-MS)
Homo sapiens
13
CARD9
64170
Two-hybrid
Homo sapiens
14
MYO15B
80022
Two-hybrid
Homo sapiens
15
MNS1
55329
Two-hybrid
Homo sapiens
16
CCHCR1
Two-hybrid
Homo sapiens
17
EPS15
2060
Affinity Capture-MS
Homo sapiens
18
TRIM27
Two-hybrid
Homo sapiens
19
CAND1
55832
Affinity Capture-MS
Homo sapiens
20
RNF208
Affinity Capture-MS
Homo sapiens
21
CCDC102B
Two-hybrid
Homo sapiens
22
STX11
8676
Two-hybrid
Homo sapiens
23
TRIM54
Two-hybrid
Homo sapiens
24
MYOZ3
Two-hybrid
Homo sapiens
25
KCTD7
154881
Two-hybrid
Homo sapiens
26
LMO2
Two-hybrid
Homo sapiens
27
PLEKHG4
Two-hybrid
Homo sapiens
28
CRACR2A
Two-hybrid
Homo sapiens
29
CEMIP
57214
Affinity Capture-MS
Homo sapiens
30
NME7
29922
Two-hybrid
Homo sapiens
31
COPS6
10980
Affinity Capture-MS
Homo sapiens
32
C19orf25
Two-hybrid
Homo sapiens
33
HGS
9146
Two-hybrid
Homo sapiens
34
COPS5
10987
Affinity Capture-MS
Homo sapiens
35
FBXO17
115290
Two-hybrid
Homo sapiens
36
KRT40
Two-hybrid
Homo sapiens
37
MAGOHB
55110
Two-hybrid
Homo sapiens
38
CCDC53
51019
Two-hybrid
Homo sapiens
39
OIP5
Two-hybrid
Homo sapiens
40
MTUS2
23281
Two-hybrid
Homo sapiens
41
KRT12
3859
Cross-Linking-MS (XL-MS)
Homo sapiens
42
U2AF1
7307
Two-hybrid
Homo sapiens
43
KRT72
140807
Cross-Linking-MS (XL-MS)
Homo sapiens
44
CEP57
Two-hybrid
Homo sapiens
45
ZWINT
Two-hybrid
Homo sapiens
46
CUL1
8454
Affinity Capture-MS
Homo sapiens
47
TFCP2
7024
Affinity Capture-MS
Homo sapiens
48
PMPCB
9512
Affinity Capture-MS
Homo sapiens
49
RCOR3
Two-hybrid
Homo sapiens
50
LMO4
Two-hybrid
Homo sapiens
51
KRT25
147183
Two-hybrid
Homo sapiens
52
C1orf216
Two-hybrid
Homo sapiens
53
GOLGA6L9
Two-hybrid
Homo sapiens
54
NFKBID
Two-hybrid
Homo sapiens
55
CXXC1
Affinity Capture-MS
Homo sapiens
56
LONRF1
Two-hybrid
Homo sapiens
57
WASH1
100287171
Two-hybrid
Homo sapiens
58
KRT34
Two-hybrid
Homo sapiens
59
BEX2
Two-hybrid
Homo sapiens
60
SPTA1
Two-hybrid
Homo sapiens
61
PRPH
5630
Two-hybrid
Homo sapiens
Cross-Linking-MS (XL-MS)
Homo sapiens
62
CUL4B
8450
Affinity Capture-MS
Homo sapiens
63
GOLGA2
2801
Two-hybrid
Homo sapiens
64
KRT35
3886
Two-hybrid
Homo sapiens
65
KRT16
3868
Cross-Linking-MS (XL-MS)
Homo sapiens
66
TNPO2
30000
Two-hybrid
Homo sapiens
67
TSSK3
Two-hybrid
Homo sapiens
68
TCHP
Two-hybrid
Homo sapiens
69
IQUB
Two-hybrid
Homo sapiens
70
KRT14
3861
Cross-Linking-MS (XL-MS)
Homo sapiens
71
DYDC1
Two-hybrid
Homo sapiens
72
KRT2
3849
Cross-Linking-MS (XL-MS)
Homo sapiens
73
CUL2
8453
Affinity Capture-MS
Homo sapiens
74
YAP1
10413
Affinity Capture-MS
Homo sapiens
75
KRT79
338785
Cross-Linking-MS (XL-MS)
Homo sapiens
76
C6orf165
Two-hybrid
Homo sapiens
77
TEKT1
Two-hybrid
Homo sapiens
78
NUMA1
4926
Affinity Capture-MS
Homo sapiens
79
GAN
8139
Affinity Capture-MS
Homo sapiens
80
KRT3
3850
Two-hybrid
Homo sapiens
Cross-Linking-MS (XL-MS)
Homo sapiens
81
KRT33B
3884
Two-hybrid
Homo sapiens
82
ASB15
142685
Two-hybrid
Homo sapiens
83
KANK2
25959
Two-hybrid
Homo sapiens
84
LCA5L
Two-hybrid
Homo sapiens
85
Kifc1
Affinity Capture-MS
Mus musculus
86
TEKT4
Two-hybrid
Homo sapiens
87
TXLNB
Two-hybrid
Homo sapiens
88
EPPK1
83481
Affinity Capture-MS
Homo sapiens
89
ZC4H2
55906
Affinity Capture-MS
Homo sapiens
90
CUL3
8452
Affinity Capture-MS
Homo sapiens
91
DES
1674
Two-hybrid
Homo sapiens
Cross-Linking-MS (XL-MS)
Homo sapiens
92
AMOT
Two-hybrid
Homo sapiens
93
KRT26
353288
Two-hybrid
Homo sapiens
94
PM20D2
135293
Two-hybrid
Homo sapiens
95
KRT27
342574
Two-hybrid
Homo sapiens
96
KRT15
3866
Two-hybrid
Homo sapiens
Cross-Linking-MS (XL-MS)
Homo sapiens
97
GPANK1
Two-hybrid
Homo sapiens
98
XPOT
11260
Two-hybrid
Homo sapiens
99
DCUN1D1
54165
Affinity Capture-MS
Homo sapiens
100
NUDT8
Affinity Capture-MS
Homo sapiens
101
GLYCTK
Two-hybrid
Homo sapiens
102
TJAP1
93643
Two-hybrid
Homo sapiens
103
KRT84
3890
Cross-Linking-MS (XL-MS)
Homo sapiens
104
USHBP1
Two-hybrid
Homo sapiens
105
CDKN2D
Two-hybrid
Homo sapiens
106
KRT19
3880
Two-hybrid
Homo sapiens
Cross-Linking-MS (XL-MS)
Homo sapiens
107
NUP62
23636
Two-hybrid
Homo sapiens
108
ALS2CR11
Two-hybrid
Homo sapiens
109
LINC00521
Two-hybrid
Homo sapiens
110
DHX15
1665
Two-hybrid
Homo sapiens
111
NUDT21
11051
Two-hybrid
Homo sapiens
112
BCAS2
10286
Two-hybrid
Homo sapiens
113
KRT36
8689
Two-hybrid
Homo sapiens
114
NEK6
10783
Two-hybrid
Homo sapiens
115
WWOX
51741
Affinity Capture-MS
Homo sapiens
Two-hybrid
Homo sapiens
116
ARMC7
Two-hybrid
Homo sapiens
117
POLR3C
10623
Two-hybrid
Homo sapiens
118
POLR1C
9533
Two-hybrid
Homo sapiens
119
KRT10
3858
Cross-Linking-MS (XL-MS)
Homo sapiens
120
INCA1
Two-hybrid
Homo sapiens
121
CDC37
11140
Two-hybrid
Homo sapiens
122
CUL5
8065
Affinity Capture-MS
Homo sapiens
123
CDK18
5129
Two-hybrid
Homo sapiens
124
LOC102724594
102724594
Two-hybrid
Homo sapiens
125
MKRN3
Two-hybrid
Homo sapiens
126
DMAP1
55929
Two-hybrid
Homo sapiens
127
KRT71
112802
Cross-Linking-MS (XL-MS)
Homo sapiens
128
EIF4A3
9775
Affinity Capture-MS
Homo sapiens
129
OSGIN1
Two-hybrid
Homo sapiens
130
Nup214
Affinity Capture-MS
Mus musculus
131
KRT24
192666
Two-hybrid
Homo sapiens
132
ABI2
10152
Two-hybrid
Homo sapiens
133
KRT20
54474
Two-hybrid
Homo sapiens
Cross-Linking-MS (XL-MS)
Homo sapiens
134
KRT38
8687
Two-hybrid
Homo sapiens
135
TRIM23
373
Two-hybrid
Homo sapiens
136
SORT1
6272
Affinity Capture-MS
Homo sapiens
137
C1orf109
Two-hybrid
Homo sapiens
138
NEDD8
4738
Affinity Capture-MS
Homo sapiens
139
HNRNPF
3185
Two-hybrid
Homo sapiens
140
KRT13
3860
Two-hybrid
Homo sapiens
141
LMO1
Two-hybrid
Homo sapiens
142
VIM
7431
Cross-Linking-MS (XL-MS)
Homo sapiens
143
KRT7
3855
Cross-Linking-MS (XL-MS)
Homo sapiens
144
CUL4A
8451
Affinity Capture-MS
Homo sapiens
View the network
image/svg+xml
Pathways in which KRT75 is involved