Gene description for TAAR2
Gene name trace amine associated receptor 2
Gene symbol TAAR2
Other names/aliases GPR58
taR-2
Species Homo sapiens
 Database cross references - TAAR2
ExoCarta ExoCarta_9287
Entrez Gene 9287
HGNC 4514
MIM 604849
UniProt Q9P1P5  
 TAAR2 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells Unpublished / Not applicable
 Gene ontology annotations for TAAR2
Molecular Function
    trace-amine receptor activity GO:0001594 IBA
    G-protein coupled receptor activity GO:0004930 TAS
Biological Process
    sensory perception of chemical stimulus GO:0007606 IBA
    positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway GO:0010579 IBA
    G-protein coupled receptor signaling pathway GO:0007186 TAS
Subcellular Localization
    integral component of membrane GO:0016021 IC
    integral component of plasma membrane GO:0005887 IBA
 Experiment description of studies that identified TAAR2 in exosomes
1
Experiment ID 126
ISEV standards
✘ EV Biophysical techniques
✔
GAPDH
EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
 Protein-protein interactions for TAAR2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which TAAR2 is involved
PathwayEvidenceSource
Amine ligand-binding receptors TAS Reactome
G alpha (s) signalling events TAS Reactome





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