Gene description for Klf7
Gene name Kruppel-like factor 7 (ubiquitous)
Gene symbol Klf7
Other names/aliases 9830124P08Rik
Species Mus musculus
 Database cross references - Klf7
ExoCarta ExoCarta_93691
Entrez Gene 93691
UniProt Q99JB0  
 Klf7 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Klf7
Molecular Function
    DNA binding GO:0003677 ISS
    metal ion binding GO:0046872 IEA
    sequence-specific DNA binding transcription factor activity GO:0003700 IDA
    nucleic acid binding GO:0003676 IEA
Biological Process
    dendrite morphogenesis GO:0048813 IMP
    positive regulation of transcription, DNA-templated GO:0045893 IDA
    axonogenesis GO:0007409 IMP
    axon guidance GO:0007411 IMP
    transcription, DNA-templated GO:0006351 IEA
    regulation of transcription, DNA-templated GO:0006355 IEA
Subcellular Localization
    nucleus GO:0005634 IEA
 Experiment description of studies that identified Klf7 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Klf7
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Klf7 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here