Gene description for Tm2d1
Gene name TM2 domain containing 1
Gene symbol Tm2d1
Other names/aliases 2310026L18Rik
AA990549
Bbp
Species Mus musculus
 Database cross references - Tm2d1
ExoCarta ExoCarta_94043
Entrez Gene 94043
UniProt Q99MB3  
 Tm2d1 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Tm2d1
Molecular Function
    beta-amyloid binding GO:0001540 IDA
    G-protein coupled receptor activity GO:0004930 IDA
Biological Process
    G-protein coupled receptor signaling pathway GO:0007186 IDA
    apoptotic signaling pathway GO:0097190 IDA
    apoptotic process GO:0006915 IEA
Subcellular Localization
    nucleoplasm GO:0005654 ISO
    integral component of membrane GO:0016021 IEA
    membrane GO:0016020 IEA
    integral component of plasma membrane GO:0005887 IDA
 Experiment description of studies that identified Tm2d1 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Tm2d1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Tm2d1 is involved
No pathways found





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