Gene description for Lrp1b
Gene name low density lipoprotein-related protein 1B (deleted in tumors)
Gene symbol Lrp1b
Other names/aliases 9630004P12Rik
Species Mus musculus
 Database cross references - Lrp1b
ExoCarta ExoCarta_94217
Entrez Gene 94217
 Lrp1b identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Lrp1b
Molecular Function
    low-density lipoprotein receptor activity GO:0005041 IDA
    protein binding GO:0005515 IPI
    calcium ion binding GO:0005509 IEA
Biological Process
    receptor-mediated endocytosis GO:0006898 IDA
    endocytosis GO:0006897 IEA
Subcellular Localization
    membrane GO:0016020 IDA
    receptor complex GO:0043235 ISO
    integral component of membrane GO:0016021 IEA
 Experiment description of studies that identified Lrp1b in exosomes
Experiment ID 15
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
Isolation/purification methods Filtration
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
 Protein-protein interactions for Lrp1b
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Lrp1b is involved
No pathways found

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