Gene description for Lrp1b
Gene name low density lipoprotein-related protein 1B (deleted in tumors)
Gene symbol Lrp1b
Other names/aliases 9630004P12Rik
LRP-DIT
Species Mus musculus
 Database cross references - Lrp1b
ExoCarta ExoCarta_94217
Vesiclepedia VP_94217
Entrez Gene 94217
 Lrp1b identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Lrp1b
Molecular Function
    low-density lipoprotein particle receptor activity GO:0005041 IBA
    low-density lipoprotein particle receptor activity GO:0005041 IDA
    calcium ion binding GO:0005509 IEA
    protein binding GO:0005515 IPI
Biological Process
    in utero embryonic development GO:0001701 IMP
    endocytosis GO:0006897 IEA
Subcellular Localization
    plasma membrane GO:0005886 IBA
    membrane GO:0016020 IDA
    receptor complex GO:0043235 IBA
    receptor complex GO:0043235 ISO
 Experiment description of studies that identified Lrp1b in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Lrp1b
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Polg  
Co-fractionation Mus musculus
2 Tmem173  
Proximity Label-MS Mus musculus
3 Vit  
Co-fractionation Mus musculus
View the network image/svg+xml
 Pathways in which Lrp1b is involved
No pathways found





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