Gene description for Tinagl1
Gene name tubulointerstitial nephritis antigen-like 1
Gene symbol Tinagl1
Other names/aliases 1110021J17Rik
AZ-1
AZ1
Arg1
Lcn7
TARP
Tinagl
Species Mus musculus
 Database cross references - Tinagl1
ExoCarta ExoCarta_94242
Entrez Gene 94242
UniProt Q99JR5  
 Tinagl1 identified in exosomes derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Tinagl1
Molecular Function
    polysaccharide binding GO:0030247 IEA
    cysteine-type peptidase activity GO:0008234 IEA
    laminin binding GO:0043236 IPI
    scavenger receptor activity GO:0005044 IEA
Biological Process
    cell adhesion GO:0007155 IBA
    immune response GO:0006955 IEA
    proteolysis GO:0006508 IEA
Subcellular Localization
    extracellular exosome GO:0070062 ISO
    extracellular matrix GO:0031012 ISO
    extracellular region GO:0005576 IEA
    cytoplasm GO:0005737 IDA
    extracellular space GO:0005615 IBA
 Experiment description of studies that identified Tinagl1 in exosomes
1
Experiment ID 210
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD81|FLOT1
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL.
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Tinagl1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Tinagl1 is involved
No pathways found





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