Gene description for Ugt1a6a
Gene name UDP glucuronosyltransferase 1 family, polypeptide A6A
Gene symbol Ugt1a6a
Other names/aliases UDPGT
UDPGT 1-6
UGT1-06
UGT1.6
Ugt1a6
Ugt1a7
Species Mus musculus
 Database cross references - Ugt1a6a
ExoCarta ExoCarta_94284
Vesiclepedia VP_94284
Entrez Gene 94284
UniProt Q64435  
 Ugt1a6a identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Ugt1a6a
Molecular Function
    glucuronosyltransferase activity GO:0015020 IDA
    glucuronosyltransferase activity GO:0015020 ISO
    enzyme binding GO:0019899 IBA
    enzyme binding GO:0019899 ISO
    protein homodimerization activity GO:0042803 ISO
    protein-containing complex binding GO:0044877 ISO
    alpha-glucuronidase activity GO:0046559 IDA
    alpha-glucuronidase activity GO:0046559 ISO
    protein heterodimerization activity GO:0046982 ISO
Biological Process
    xenobiotic metabolic process GO:0006805 ISO
    4-chlorobiphenyl metabolic process GO:0018880 ISO
    glucuronate metabolic process GO:0019585 IDA
    glucuronate metabolic process GO:0019585 ISO
    L-ascorbic acid biosynthetic process GO:0019853 IGI
    cellular glucuronidation GO:0052695 IBA
    cellular glucuronidation GO:0052695 ISO
    cellular response to glucocorticoid stimulus GO:0071385 ISO
Subcellular Localization
    mitochondrial inner membrane GO:0005743 HDA
    endoplasmic reticulum GO:0005783 IBA
    endoplasmic reticulum GO:0005783 ISO
    endoplasmic reticulum membrane GO:0005789 IEA
    protein-containing complex GO:0032991 ISO
    intracellular membrane-bounded organelle GO:0043231 ISO
 Experiment description of studies that identified Ugt1a6a in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Ugt1a6a
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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