Gene description for ACAP1
Gene name ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
Gene symbol ACAP1
Other names/aliases CENTB1
Species Homo sapiens
 Database cross references - ACAP1
ExoCarta ExoCarta_9744
Entrez Gene 9744
HGNC 16467
MIM 607763
UniProt Q15027  
 ACAP1 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for ACAP1
Molecular Function
    GTPase activator activity GO:0005096 IEA
    protein binding GO:0005515 IPI
    metal ion binding GO:0046872 IEA
Biological Process
    protein transport GO:0015031 IEA
    positive regulation of GTPase activity GO:0043547 IEA
Subcellular Localization
    recycling endosome membrane GO:0055038 IEA
    membrane GO:0016020 IDA
 Experiment description of studies that identified ACAP1 in exosomes
1
Experiment ID 217
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101
EV Cytosolic markers
✔
CD81|CD9|CD63
EV Membrane markers
✘ EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for ACAP1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 HOM-TES-103  
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which ACAP1 is involved
No pathways found





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