Gene description for Abtb2
Gene name ankyrin repeat and BTB (POZ) domain containing 2
Gene symbol Abtb2
Other names/aliases AW539457
BPOZ-2
Species Mus musculus
 Database cross references - Abtb2
ExoCarta ExoCarta_99382
Entrez Gene 99382
UniProt Q7TQI7  
 Abtb2 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Abtb2
Molecular Function
    molecular_function GO:0003674 ND
    protein heterodimerization activity GO:0046982 IEA
Biological Process
    cellular response to toxic substance GO:0097237 IMP
Subcellular Localization
    nucleus GO:0005634 ISO
    nucleoplasm GO:0005654 ISO
 Experiment description of studies that identified Abtb2 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Abtb2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Abtb2 is involved
No pathways found





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