 Description for Phosphatidylcholine |
| Lipid |
Phosphatidylcholine |
| Species |
Homo sapiens |
| Phosphatidylcholine identified in sEVs derived from the following tissue/cell type |
|
Astrocytes
|
25498500
|
|
Faeces
|
33431899
|
|
Faeces
|
33431899
|
|
Glioblastoma cells
|
25498500
|
|
Prostate cancer cells
|
25519911
|
|
Prostate cancer cells
|
25519911
|
|
Prostate cancer cells
|
25519911
|
| Experiment description of studies that identified Phosphatidylcholine in sEVs |
| 1 |
| Experiment ID |
273 |
| Identified molecule |
Lipid 
|
| Identification method |
Thin-layer chromatography
|
| PubMed ID |
25498500
|
| Organism |
Homo sapiens |
| Experiment description |
Effective internalization of U251-MG-secreted exosomes into cancer cells and characterization of their lipid components. |
| Authors |
"Toda Y, Takata K, Nakagawa Y, Kawakami H, Fujioka S, Kobayashi K, Hattori Y, Kitamura Y, Akaji K, Ashihara E." |
| Journal name |
Biochem Biophys Res Commun
|
| Publication year |
2015 |
| Sample |
Astrocytes |
| Sample name |
Astrocytes |
| Molecules identified in the study |
Lipids |
| Methods used in the study |
Thin layer chromatography |
|
|
| 2 |
| Experiment ID |
305 |
| Identified molecule |
Lipid
|
| Identification method |
HPLC
|
| PubMed ID |
33431899
|
| Organism |
Homo sapiens |
| Experiment description |
High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance |
| Authors |
"Kumar A, Sundaram K, Mu J, Dryden GW, Sriwastva MK, Lei C, Zhang L, Qiu X, Xu F, Yan J, Zhang X, Park JW, Merchant ML, Bohler HCL, Wang B, Zhang S, Qin C, Xu Z, Han X, McClain CJ, Teng Y, Zhang HG." |
| Journal name |
Nat Commun
|
| Publication year |
2021 |
| Sample |
Faeces |
| Sample name |
Healthy volunteers |
| Molecules identified in the study |
Protein
Lipid |
| Methods used in the study |
Western blotting
Mass spectrometry
Immunofluorescence
HPLC |
|
|
| 3 |
| Experiment ID |
306 |
| Identified molecule |
Lipid
|
| Identification method |
HPLC
|
| PubMed ID |
33431899
|
| Organism |
Homo sapiens |
| Experiment description |
High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance |
| Authors |
"Kumar A, Sundaram K, Mu J, Dryden GW, Sriwastva MK, Lei C, Zhang L, Qiu X, Xu F, Yan J, Zhang X, Park JW, Merchant ML, Bohler HCL, Wang B, Zhang S, Qin C, Xu Z, Han X, McClain CJ, Teng Y, Zhang HG." |
| Journal name |
Nat Commun
|
| Publication year |
2021 |
| Sample |
Faeces |
| Sample name |
Type 2 diabetes patients |
| Molecules identified in the study |
Protein
Lipid |
| Methods used in the study |
Western blotting
Mass spectrometry
Immunofluorescence
HPLC |
|
|
| 4 |
| Experiment ID |
272 |
| Identified molecule |
Lipid
|
| Identification method |
Thin-layer chromatography
|
| PubMed ID |
25498500
|
| Organism |
Homo sapiens |
| Experiment description |
Effective internalization of U251-MG-secreted exosomes into cancer cells and characterization of their lipid components. |
| Authors |
"Toda Y, Takata K, Nakagawa Y, Kawakami H, Fujioka S, Kobayashi K, Hattori Y, Kitamura Y, Akaji K, Ashihara E." |
| Journal name |
Biochem Biophys Res Commun
|
| Publication year |
2015 |
| Sample |
Glioblastoma cells |
| Sample name |
U251 |
| Molecules identified in the study |
Lipids
Protein |
| Methods used in the study |
Thin layer chromatography
Western blotting |
|
|
| 5 |
| Experiment ID |
245 |
| Identified molecule |
Lipid
|
| Identification method |
LC-MS
|
| PubMed ID |
25519911
|
| Organism |
Homo sapiens |
| Experiment description |
The ether lipid precursor hexadecylglycerol stimulates the release and changes the composition of exosomes derived from PC-3 cells |
| Authors |
"Phuyal S, Skotland T, Hessvik NP, Simolin H, Overbye A, Brech A, Parton RG, Ekroos K, Sandvig K, Llorente A." |
| Journal name |
J Biol Chem
|
| Publication year |
2015 |
| Sample |
Prostate cancer cells |
| Sample name |
PC-3 - Ethanol treated (control) |
| Molecules identified in the study |
Lipids
Protein |
| Methods used in the study |
Western blotting
Mass spectrometry |
|
|
| 6 |
| Experiment ID |
246 |
| Identified molecule |
Lipid
|
| Identification method |
LC-MS
|
| PubMed ID |
25519911
|
| Organism |
Homo sapiens |
| Experiment description |
The ether lipid precursor hexadecylglycerol stimulates the release and changes the composition of exosomes derived from PC-3 cells |
| Authors |
"Phuyal S, Skotland T, Hessvik NP, Simolin H, Overbye A, Brech A, Parton RG, Ekroos K, Sandvig K, Llorente A." |
| Journal name |
J Biol Chem
|
| Publication year |
2015 |
| Sample |
Prostate cancer cells |
| Sample name |
PC-3 - sn-1-O-hexadecylglycerol treated |
| Molecules identified in the study |
Lipids |
| Methods used in the study |
Western blotting
Mass spectrometry |
|
|
| 7 |
| Experiment ID |
247 |
| Identified molecule |
Lipid
|
| Identification method |
LC-MS
|
| PubMed ID |
25519911
|
| Organism |
Homo sapiens |
| Experiment description |
The ether lipid precursor hexadecylglycerol stimulates the release and changes the composition of exosomes derived from PC-3 cells |
| Authors |
"Phuyal S, Skotland T, Hessvik NP, Simolin H, Overbye A, Brech A, Parton RG, Ekroos K, Sandvig K, Llorente A." |
| Journal name |
J Biol Chem
|
| Publication year |
2015 |
| Sample |
Prostate cancer cells |
| Sample name |
PC-3 - DL- palmitin treated |
| Molecules identified in the study |
Lipids |
| Methods used in the study |
Western blotting
Mass spectrometry |
|
|