 miRNA description for let-7a-5p |
| miRNA accession |
let-7a-5p |
| Species |
Homo sapiens |
| let-7a-5p identified in sEVs derived from the following tissue/cell type |
|
Colorectal cancer cells
|
25330373
|
|
Colorectal cancer cells
|
29472616
|
|
Colorectal cancer cells
|
29472616
|
|
Colorectal cancer cells
|
29472616
|
|
Posterior longitudinal ligament
|
35513391
|
| Experiment description of studies that identified let-7a-5p in sEVs |
| 1 |
| Experiment ID |
223 |
| Identified molecule |
miRNA
|
| Identification method |
|
| PubMed ID |
25330373
|
| Organism |
Homo sapiens |
| Experiment description |
Deep sequencing of RNA from three different extracellular vesicle (EV) subtypes released from the human LIM1863 colon cancer cell line uncovers distinct miRNA-enrichment signatures |
| Authors |
"Ji H, Chen M, Greening DW, He W, Rai A, Zhang W, Simpson RJ" |
| Journal name |
PLoS One
|
| Publication year |
2014 |
| Sample |
Colorectal cancer cells |
| Sample name |
LIM1863 |
| Molecules identified in the study |
miRNA
Protein |
| Methods used in the study |
RT-PCR
Western blotting |
|
|
| 2 |
| Experiment ID |
339 |
| Identified molecule |
miRNA
|
| Identification method |
|
| PubMed ID |
29472616
|
| Organism |
Homo sapiens |
| Experiment description |
Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 |
| Authors |
"Cooks T, Pateras IS, Jenkins LM, Patel KM, Robles AI, Morris J, Forshew T, Appella E, Gorgoulis VG, Harris CC." |
| Journal name |
Nat Commun
|
| Publication year |
2018 |
| Sample |
Colorectal cancer cells |
| Sample name |
HCT116 |
| Molecules identified in the study |
Protein
miRNA |
| Methods used in the study |
Western blotting
miR-chip array |
|
|
| 3 |
| Experiment ID |
340 |
| Identified molecule |
miRNA
|
| Identification method |
|
| PubMed ID |
29472616
|
| Organism |
Homo sapiens |
| Experiment description |
Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 |
| Authors |
"Cooks T, Pateras IS, Jenkins LM, Patel KM, Robles AI, Morris J, Forshew T, Appella E, Gorgoulis VG, Harris CC." |
| Journal name |
Nat Commun
|
| Publication year |
2018 |
| Sample |
Colorectal cancer cells |
| Sample name |
HCT116 |
| Molecules identified in the study |
Protein
miRNA |
| Methods used in the study |
Western blotting
miR-chip array |
|
|
| 4 |
| Experiment ID |
341 |
| Identified molecule |
miRNA
|
| Identification method |
|
| PubMed ID |
29472616
|
| Organism |
Homo sapiens |
| Experiment description |
Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 |
| Authors |
"Cooks T, Pateras IS, Jenkins LM, Patel KM, Robles AI, Morris J, Forshew T, Appella E, Gorgoulis VG, Harris CC." |
| Journal name |
Nat Commun
|
| Publication year |
2018 |
| Sample |
Colorectal cancer cells |
| Sample name |
HCT116 |
| Molecules identified in the study |
Protein
miRNA |
| Methods used in the study |
Western blotting
miR-chip array |
|
|
| 5 |
| Experiment ID |
869 |
| Identified molecule |
miRNA
|
| Identification method |
|
| PubMed ID |
35513391
|
| Organism |
Homo sapiens |
| Experiment description |
Small extracellular vesicle-mediated miR-320e transmission promotes osteogenesis in OPLL by targeting TAK1 |
| Authors |
"Xu C, Zhang Z, Liu N, Li L, Zhong H, Wang R, Shi Q, Zhang Z, Wei L, Hu B, Zhang H, Shen X, Wang Y, Liu Y, Yuan W." |
| Journal name |
Nat Commun
|
| Publication year |
2022 |
| Sample |
Posterior longitudinal ligament |
| Sample name |
Posterior longitudinal ligament cells |
| Molecules identified in the study |
miRNA |
| Methods used in the study |
RNA sequencing
qRT-PCR |
|
|