 miRNA description for let-7c |
| miRNA accession |
let-7c |
| Species |
Mus musculus |
| let-7c identified in sEVs derived from the following tissue/cell type |
|
Breast cancer cells
|
35173168
|
|
Breast cancer cells
|
35173168
|
|
Mast cells
|
17486113
|
|
Serum
|
35173168
|
|
Serum
|
35173168
|
|
Serum
|
35173168
|
|
Serum
|
35173168
|
|
Serum
|
35173168
|
|
Serum
|
35173168
|
| Experiment description of studies that identified let-7c in sEVs |
| 1 |
| Experiment ID |
871 |
| Identified molecule |
miRNA
|
| Identification method |
|
| PubMed ID |
35173168
|
| Organism |
Mus musculus |
| Experiment description |
Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression |
| Authors |
"Qi M, Xia Y, Wu Y, Zhang Z, Wang X, Lu L, Dai C, Song Y, Xu K, Ji W, Zhan L." |
| Journal name |
Nat Commun
|
| Publication year |
2022 |
| Sample |
Breast cancer cells |
| Sample name |
BALB/c bearing 4T07 primary tumour |
| Molecules identified in the study |
miRNA |
| Methods used in the study |
qRT-PCR |
|
|
| 2 |
| Experiment ID |
872 |
| Identified molecule |
miRNA
|
| Identification method |
|
| PubMed ID |
35173168
|
| Organism |
Mus musculus |
| Experiment description |
Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression |
| Authors |
"Qi M, Xia Y, Wu Y, Zhang Z, Wang X, Lu L, Dai C, Song Y, Xu K, Ji W, Zhan L." |
| Journal name |
Nat Commun
|
| Publication year |
2022 |
| Sample |
Breast cancer cells |
| Sample name |
BALB/c bearing Lin28B overexpressed 4T07 primary tumour |
| Molecules identified in the study |
miRNA |
| Methods used in the study |
qRT-PCR |
|
|
| 3 |
| Experiment ID |
15 |
| Identified molecule |
miRNA
|
| Identification method |
|
| PubMed ID |
17486113
|
| Organism |
Mus musculus
Homo sapiens |
| Experiment description |
Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. |
| Authors |
"Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO" |
| Journal name |
NCB
|
| Publication year |
2007 |
| Sample |
Mast cells |
| Sample name |
MC9
Bone marrow-derived mast cells
HMC-1 |
| Molecules identified in the study |
Protein
mRNA
miRNA |
| Methods used in the study |
Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array |
|
|
| 4 |
| Experiment ID |
870 |
| Identified molecule |
miRNA
|
| Identification method |
|
| PubMed ID |
35173168
|
| Organism |
Mus musculus |
| Experiment description |
Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression |
| Authors |
"Qi M, Xia Y, Wu Y, Zhang Z, Wang X, Lu L, Dai C, Song Y, Xu K, Ji W, Zhan L." |
| Journal name |
Nat Commun
|
| Publication year |
2022 |
| Sample |
Serum |
| Sample name |
BALB/c bearing 4T07 primary tumour |
| Molecules identified in the study |
Protein
mRNA |
| Methods used in the study |
Western blotting
RNA sequencing
qRT-PCR |
|
|
| 5 |
| Experiment ID |
873 |
| Identified molecule |
miRNA
|
| Identification method |
|
| PubMed ID |
35173168
|
| Organism |
Mus musculus |
| Experiment description |
Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression |
| Authors |
"Qi M, Xia Y, Wu Y, Zhang Z, Wang X, Lu L, Dai C, Song Y, Xu K, Ji W, Zhan L." |
| Journal name |
Nat Commun
|
| Publication year |
2022 |
| Sample |
Serum |
| Sample name |
BALB/c bearing Lin28B overexpressed 4T07 primary tumour |
| Molecules identified in the study |
miRNA |
| Methods used in the study |
qRT-PCR |
|
|
| 6 |
| Experiment ID |
874 |
| Identified molecule |
miRNA
|
| Identification method |
|
| PubMed ID |
35173168
|
| Organism |
Mus musculus |
| Experiment description |
Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression |
| Authors |
"Qi M, Xia Y, Wu Y, Zhang Z, Wang X, Lu L, Dai C, Song Y, Xu K, Ji W, Zhan L." |
| Journal name |
Nat Commun
|
| Publication year |
2022 |
| Sample |
Serum |
| Sample name |
PyMT control mice |
| Molecules identified in the study |
miRNA |
| Methods used in the study |
qRT-PCR |
|
|
| 7 |
| Experiment ID |
875 |
| Identified molecule |
miRNA
|
| Identification method |
|
| PubMed ID |
35173168
|
| Organism |
Mus musculus |
| Experiment description |
Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression |
| Authors |
"Qi M, Xia Y, Wu Y, Zhang Z, Wang X, Lu L, Dai C, Song Y, Xu K, Ji W, Zhan L." |
| Journal name |
Nat Commun
|
| Publication year |
2022 |
| Sample |
Serum |
| Sample name |
PyMT Lin28B knockin mice |
| Molecules identified in the study |
miRNA |
| Methods used in the study |
qRT-PCR |
|
|
| 8 |
| Experiment ID |
876 |
| Identified molecule |
miRNA
|
| Identification method |
|
| PubMed ID |
35173168
|
| Organism |
Mus musculus |
| Experiment description |
Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression |
| Authors |
"Qi M, Xia Y, Wu Y, Zhang Z, Wang X, Lu L, Dai C, Song Y, Xu K, Ji W, Zhan L." |
| Journal name |
Nat Commun
|
| Publication year |
2022 |
| Sample |
Serum |
| Sample name |
MMTV-Neu control mice |
| Molecules identified in the study |
miRNA |
| Methods used in the study |
qRT-PCR |
|
|
| 9 |
| Experiment ID |
877 |
| Identified molecule |
miRNA
|
| Identification method |
|
| PubMed ID |
35173168
|
| Organism |
Mus musculus |
| Experiment description |
Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression |
| Authors |
"Qi M, Xia Y, Wu Y, Zhang Z, Wang X, Lu L, Dai C, Song Y, Xu K, Ji W, Zhan L." |
| Journal name |
Nat Commun
|
| Publication year |
2022 |
| Sample |
Serum |
| Sample name |
MMTV-Neu Lin28B knockin mice |
| Molecules identified in the study |
miRNA |
| Methods used in the study |
qRT-PCR |
|
|