 miRNA description for let-7i |
| miRNA accession |
let-7i |
| Species |
Homo sapiens |
| let-7i identified in sEVs derived from the following tissue/cell type |
|
Dendritic cells
|
21505438
|
|
Endothelial cells
|
26027894
|
|
Plasma
|
29295981
|
|
Plasma
|
29295981
|
|
Plasma
|
29295981
|
|
Plasma
|
29295981
|
|
Plasma
|
29295981
|
|
Plasma
|
29295981
|
|
Plasma
|
29295981
|
|
Plasma
|
29295981
|
|
Serum
|
18589210
|
|
Stomach cancer cells
|
20949044
|
|
Stomach cancer cells
|
20949044
|
|
T cells
|
21505438
|
| Experiment description of studies that identified let-7i in sEVs |
| 1 |
| Experiment ID |
117 |
| Identified molecule |
miRNA
|
| Identification method |
| Human miRNA Microarray Kit |
|
|
| PubMed ID |
21505438
|
| Organism |
Homo sapiens |
| Experiment description |
Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells. |
| Authors |
"Mittelbrunn M, Gutierrez-Vázquez C, Villarroya-Beltri C, González S, Sánchez-Cabo F, González MÃÂ, Bernad A, Sánchez-Madrid F." |
| Journal name |
NATCOM
|
| Publication year |
2011 |
| Sample |
Dendritic cells |
| Sample name |
Dendritic cells |
| Molecules identified in the study |
Protein
miRNA |
| Methods used in the study |
Mass spectrometry
Microarray |
|
|
| 2 |
| Experiment ID |
226 |
| Identified molecule |
miRNA
|
| Identification method |
| Small RNA sequencing (Illumina HiSeq 2000 (Solexa) |
|
|
| PubMed ID |
26027894
|
| Organism |
Homo sapiens |
| Experiment description |
"Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting" |
| Authors |
"Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar" |
| Journal name |
Journal of Extracellular Vesicles
|
| Publication year |
2015 |
| Sample |
Endothelial cells |
| Sample name |
HMEC-1 |
| Molecules identified in the study |
miRNA
Protein
snoRNA
lncRNA
yRNA
snRNA
mRNA
ncRNA
mtRNA
vtRNA
scaRNA
lincRNA |
| Methods used in the study |
Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
Western blotting |
|
|
| 3 |
| Experiment ID |
614 |
| Identified molecule |
miRNA
|
| Identification method |
|
| PubMed ID |
29295981
|
| Organism |
Homo sapiens |
| Experiment description |
Circulating exosomes suppress the induction of regulatory T cells via let-7i in multiple sclerosis |
| Authors |
"Kimura K, Hohjoh H, Fukuoka M, Sato W, Oki S, Tomi C, Yamaguchi H, Kondo T, Takahashi R, Yamamura T." |
| Journal name |
Nat Commun
|
| Publication year |
2018 |
| Sample |
Plasma |
| Sample name |
Healthy controls |
| Molecules identified in the study |
Protein
miRNA |
| Methods used in the study |
Western blotting
Microarray
RT-qPCR |
|
|
| 4 |
| Experiment ID |
615 |
| Identified molecule |
miRNA
|
| Identification method |
|
| PubMed ID |
29295981
|
| Organism |
Homo sapiens |
| Experiment description |
Circulating exosomes suppress the induction of regulatory T cells via let-7i in multiple sclerosis |
| Authors |
"Kimura K, Hohjoh H, Fukuoka M, Sato W, Oki S, Tomi C, Yamaguchi H, Kondo T, Takahashi R, Yamamura T." |
| Journal name |
Nat Commun
|
| Publication year |
2018 |
| Sample |
Plasma |
| Sample name |
Multiple sclerosis |
| Molecules identified in the study |
miRNA |
| Methods used in the study |
Microarray
RT-qPCR |
|
|
| 5 |
| Experiment ID |
616 |
| Identified molecule |
miRNA
|
| Identification method |
|
| PubMed ID |
29295981
|
| Organism |
Homo sapiens |
| Experiment description |
Circulating exosomes suppress the induction of regulatory T cells via let-7i in multiple sclerosis |
| Authors |
"Kimura K, Hohjoh H, Fukuoka M, Sato W, Oki S, Tomi C, Yamaguchi H, Kondo T, Takahashi R, Yamamura T." |
| Journal name |
Nat Commun
|
| Publication year |
2018 |
| Sample |
Plasma |
| Sample name |
Relapsing-remitting multiple sclerosis |
| Molecules identified in the study |
miRNA |
| Methods used in the study |
RT-qPCR |
|
|
| 6 |
| Experiment ID |
617 |
| Identified molecule |
miRNA
|
| Identification method |
|
| PubMed ID |
29295981
|
| Organism |
Homo sapiens |
| Experiment description |
Circulating exosomes suppress the induction of regulatory T cells via let-7i in multiple sclerosis |
| Authors |
"Kimura K, Hohjoh H, Fukuoka M, Sato W, Oki S, Tomi C, Yamaguchi H, Kondo T, Takahashi R, Yamamura T." |
| Journal name |
Nat Commun
|
| Publication year |
2018 |
| Sample |
Plasma |
| Sample name |
Secondary-progressive multiple sclerosis |
| Molecules identified in the study |
miRNA |
| Methods used in the study |
RT-qPCR |
|
|
| 7 |
| Experiment ID |
618 |
| Identified molecule |
miRNA
|
| Identification method |
|
| PubMed ID |
29295981
|
| Organism |
Homo sapiens |
| Experiment description |
Circulating exosomes suppress the induction of regulatory T cells via let-7i in multiple sclerosis |
| Authors |
"Kimura K, Hohjoh H, Fukuoka M, Sato W, Oki S, Tomi C, Yamaguchi H, Kondo T, Takahashi R, Yamamura T." |
| Journal name |
Nat Commun
|
| Publication year |
2018 |
| Sample |
Plasma |
| Sample name |
Multiple sclerosis in remission phase |
| Molecules identified in the study |
miRNA |
| Methods used in the study |
RT-qPCR |
|
|
| 8 |
| Experiment ID |
619 |
| Identified molecule |
miRNA
|
| Identification method |
|
| PubMed ID |
29295981
|
| Organism |
Homo sapiens |
| Experiment description |
Circulating exosomes suppress the induction of regulatory T cells via let-7i in multiple sclerosis |
| Authors |
"Kimura K, Hohjoh H, Fukuoka M, Sato W, Oki S, Tomi C, Yamaguchi H, Kondo T, Takahashi R, Yamamura T." |
| Journal name |
Nat Commun
|
| Publication year |
2018 |
| Sample |
Plasma |
| Sample name |
Multiple sclerosis in relapse phase |
| Molecules identified in the study |
miRNA |
| Methods used in the study |
RT-qPCR |
|
|
| 9 |
| Experiment ID |
620 |
| Identified molecule |
miRNA
|
| Identification method |
|
| PubMed ID |
29295981
|
| Organism |
Homo sapiens |
| Experiment description |
Circulating exosomes suppress the induction of regulatory T cells via let-7i in multiple sclerosis |
| Authors |
"Kimura K, Hohjoh H, Fukuoka M, Sato W, Oki S, Tomi C, Yamaguchi H, Kondo T, Takahashi R, Yamamura T." |
| Journal name |
Nat Commun
|
| Publication year |
2018 |
| Sample |
Plasma |
| Sample name |
Male with multiple sclerosis |
| Molecules identified in the study |
miRNA |
| Methods used in the study |
RT-qPCR |
|
|
| 10 |
| Experiment ID |
621 |
| Identified molecule |
miRNA
|
| Identification method |
|
| PubMed ID |
29295981
|
| Organism |
Homo sapiens |
| Experiment description |
Circulating exosomes suppress the induction of regulatory T cells via let-7i in multiple sclerosis |
| Authors |
"Kimura K, Hohjoh H, Fukuoka M, Sato W, Oki S, Tomi C, Yamaguchi H, Kondo T, Takahashi R, Yamamura T." |
| Journal name |
Nat Commun
|
| Publication year |
2018 |
| Sample |
Plasma |
| Sample name |
Female with multiple sclerosis |
| Molecules identified in the study |
miRNA |
| Methods used in the study |
RT-qPCR |
|
|
| 11 |
| Experiment ID |
45 |
| Identified molecule |
miRNA
|
| Identification method |
|
| PubMed ID |
18589210
|
| Organism |
Homo sapiens |
| Experiment description |
MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer. |
| Authors |
"Taylor DD, Gercel-Taylor C" |
| Journal name |
GO
|
| Publication year |
2008 |
| Sample |
Serum |
| Sample name |
Serum - Papillary adenocarcinoma of ovary |
| Molecules identified in the study |
Protein
miRNA |
| Methods used in the study |
Western blotting
467microRNA Array |
|
|
| 12 |
| Experiment ID |
88 |
| Identified molecule |
miRNA
|
| Identification method |
Human miRNA Microarray Kit
RT-PCR |
|
|
| PubMed ID |
20949044
|
| Organism |
Homo sapiens |
| Experiment description |
Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line |
| Authors |
"Ohshima K, Inoue K, Fujiwara A, Hatakeyama K, Kanto K, Watanabe Y, Muramatsu K, Fukuda Y, Ogura S, Yamaguchi K, Mochizuki T." |
| Journal name |
PLoS One
|
| Publication year |
2010 |
| Sample |
Stomach cancer cells |
| Sample name |
AZ-P7a |
| Molecules identified in the study |
Protein
miRNA |
| Methods used in the study |
Immunoelectron Microscopy
Western blotting
RT-PCR
Human miRNA Microarray Kit |
|
|
| 13 |
| Experiment ID |
82 |
| Identified molecule |
miRNA
|
| Identification method |
|
| PubMed ID |
20949044
|
| Organism |
Homo sapiens |
| Experiment description |
Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line |
| Authors |
"Ohshima K, Inoue K, Fujiwara A, Hatakeyama K, Kanto K, Watanabe Y, Muramatsu K, Fukuda Y, Ogura S, Yamaguchi K, Mochizuki T." |
| Journal name |
PLoS One
|
| Publication year |
2010 |
| Sample |
Stomach cancer cells |
| Sample name |
AZ-521 |
| Molecules identified in the study |
Protein
miRNA |
| Methods used in the study |
Western blotting
RT-PCR
Human miRNA Microarray Kit |
|
|
| 14 |
| Experiment ID |
115 |
| Identified molecule |
miRNA
|
| Identification method |
| Human miRNA Microarray Kit |
|
|
| PubMed ID |
21505438
|
| Organism |
Homo sapiens |
| Experiment description |
Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells. |
| Authors |
"Mittelbrunn M, Gutierrez-Vázquez C, Villarroya-Beltri C, González S, Sánchez-Cabo F, González MÃÂ, Bernad A, Sánchez-Madrid F." |
| Journal name |
NATCOM
|
| Publication year |
2011 |
| Sample |
T cells |
| Sample name |
J77 |
| Molecules identified in the study |
Protein
miRNA |
| Methods used in the study |
Mass spectrometry
Microarray |
|
|