 miRNA description for miR-146a-5p |
| miRNA accession |
miR-146a-5p |
| Species |
Homo sapiens |
| miR-146a-5p identified in sEVs derived from the following tissue/cell type |
|
Colorectal cancer cells
|
25330373
|
|
Colorectal cancer cells
|
35443745
|
|
Colorectal cancer cells
|
35443745
|
|
Mesenchymal stem cells
|
33479185
|
| Experiment description of studies that identified miR-146a-5p in sEVs |
| 1 |
| Experiment ID |
223 |
| Identified molecule |
miRNA
|
| Identification method |
|
| PubMed ID |
25330373
|
| Organism |
Homo sapiens |
| Experiment description |
Deep sequencing of RNA from three different extracellular vesicle (EV) subtypes released from the human LIM1863 colon cancer cell line uncovers distinct miRNA-enrichment signatures |
| Authors |
"Ji H, Chen M, Greening DW, He W, Rai A, Zhang W, Simpson RJ" |
| Journal name |
PLoS One
|
| Publication year |
2014 |
| Sample |
Colorectal cancer cells |
| Sample name |
LIM1863 |
| Molecules identified in the study |
miRNA
Protein |
| Methods used in the study |
RT-PCR
Western blotting |
|
|
| 2 |
| Experiment ID |
763 |
| Identified molecule |
miRNA
|
| Identification method |
|
| PubMed ID |
35443745
|
| Organism |
Homo sapiens |
| Experiment description |
Exosomal miR-146a-5p and miR-155-5p promote CXCL12/CXCR7-induced metastasis of colorectal cancer by crosstalk with cancer-associated fibroblasts |
| Authors |
"Wang D, Wang X, Song Y, Si M, Sun Y, Liu X, Cui S, Qu X, Yu X." |
| Journal name |
Cell Death Dis
|
| Publication year |
2022 |
| Sample |
Colorectal cancer cells |
| Sample name |
HCT116 |
| Molecules identified in the study |
Protein
miRNA |
| Methods used in the study |
Western blotting
RNA sequencing
RT-qPCR |
|
|
| 3 |
| Experiment ID |
764 |
| Identified molecule |
miRNA
|
| Identification method |
|
| PubMed ID |
35443745
|
| Organism |
Homo sapiens |
| Experiment description |
Exosomal miR-146a-5p and miR-155-5p promote CXCL12/CXCR7-induced metastasis of colorectal cancer by crosstalk with cancer-associated fibroblasts |
| Authors |
"Wang D, Wang X, Song Y, Si M, Sun Y, Liu X, Cui S, Qu X, Yu X." |
| Journal name |
Cell Death Dis
|
| Publication year |
2022 |
| Sample |
Colorectal cancer cells |
| Sample name |
HCT116 |
| Molecules identified in the study |
Protein
miRNA |
| Methods used in the study |
Western blotting
RNA sequencing
RT-qPCR |
|
|
| 4 |
| Experiment ID |
372 |
| Identified molecule |
miRNA
|
| Identification method |
|
| PubMed ID |
33479185
|
| Organism |
Homo sapiens |
| Experiment description |
Human umbilical cord mesenchymal stem cell-derived exosomal miR-146a-5p reduces microglial-mediated neuroinflammation via suppression of the IRAK1/TRAF6 signaling pathway after ischemic stroke |
| Authors |
"Zhang Z, Zou X, Zhang R, Xie Y, Feng Z, Li F, Han J, Sun H, Ouyang Q, Hua S, Lv B, Hua T, Liu Z, Cai Y, Zou Y, Tang Y, Jiang X." |
| Journal name |
Aging
|
| Publication year |
2021 |
| Sample |
Mesenchymal stem cells |
| Sample name |
hUMSCs |
| Molecules identified in the study |
Protein
miRNA |
| Methods used in the study |
Western blotting
Microarray |
|
|