miRNA description for miR-19a
miRNA accession miR-19a
Species Homo sapiens
 miR-19a identified in sEVs derived from the following tissue/cell type
Breast cancer cells 34465793    
Breast cancer cells 34465793    
Breast cancer cells 34465793    
Breast cancer cells 34465793    
Breast cancer cells 34465793    
Breast cancer cells 34465793    
Breast cancer cells 34465793    
Breast cancer cells 34465793    
Breast cancer cells 34465793    
Breast cancer cells 34465793    
Breast cancer cells 34465793    
Dendritic cells 21505438    
Serum 18589210    
Serum 34465793    
Serum 34465793    
Serum 34465793    
Serum 34465793    
Serum 34465793    
Serum 34465793    
Serum 34465793    
T cells 21505438    
 Experiment description of studies that identified miR-19a in sEVs
1
Experiment ID 701
Identified molecule miRNA
Identification method
qPCR   
PubMed ID 34465793    
Organism Homo sapiens
Experiment description Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer
Authors "Wu K, Feng J, Lyu F, Xing F, Sharma S, Liu Y, Wu SY, Zhao D, Tyagi A, Deshpande RP, Pei X, Ruiz MG, Takahashi H, Tsuzuki S, Kimura T, Mo YY, Shiozawa Y, Singh R, Watabe K."
Journal name Nat Commun
Publication year 2021
Sample Breast cancer cells
Sample name T47D - 100K pellet
Molecules identified in the study miRNA
Methods used in the study qPCR
2
Experiment ID 702
Identified molecule miRNA
Identification method
qPCR   
PubMed ID 34465793    
Organism Homo sapiens
Experiment description Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer
Authors "Wu K, Feng J, Lyu F, Xing F, Sharma S, Liu Y, Wu SY, Zhao D, Tyagi A, Deshpande RP, Pei X, Ruiz MG, Takahashi H, Tsuzuki S, Kimura T, Mo YY, Shiozawa Y, Singh R, Watabe K."
Journal name Nat Commun
Publication year 2021
Sample Breast cancer cells
Sample name T47DBoM - 100K pellet
Molecules identified in the study miRNA
Methods used in the study qPCR
3
Experiment ID 710
Identified molecule miRNA
Identification method
qPCR   
PubMed ID 34465793    
Organism Homo sapiens
Experiment description Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer
Authors "Wu K, Feng J, Lyu F, Xing F, Sharma S, Liu Y, Wu SY, Zhao D, Tyagi A, Deshpande RP, Pei X, Ruiz MG, Takahashi H, Tsuzuki S, Kimura T, Mo YY, Shiozawa Y, Singh R, Watabe K."
Journal name Nat Commun
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - 100K pellet
Molecules identified in the study miRNA
Methods used in the study qPCR
4
Experiment ID 711
Identified molecule miRNA
Identification method
qPCR   
PubMed ID 34465793    
Organism Homo sapiens
Experiment description Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer
Authors "Wu K, Feng J, Lyu F, Xing F, Sharma S, Liu Y, Wu SY, Zhao D, Tyagi A, Deshpande RP, Pei X, Ruiz MG, Takahashi H, Tsuzuki S, Kimura T, Mo YY, Shiozawa Y, Singh R, Watabe K."
Journal name Nat Commun
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231BoM-1833 - 100K pellet
Molecules identified in the study miRNA
Methods used in the study qPCR
5
Experiment ID 712
Identified molecule miRNA
Identification method
qPCR   
PubMed ID 34465793    
Organism Homo sapiens
Experiment description Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer
Authors "Wu K, Feng J, Lyu F, Xing F, Sharma S, Liu Y, Wu SY, Zhao D, Tyagi A, Deshpande RP, Pei X, Ruiz MG, Takahashi H, Tsuzuki S, Kimura T, Mo YY, Shiozawa Y, Singh R, Watabe K."
Journal name Nat Commun
Publication year 2021
Sample Breast cancer cells
Sample name Serum - nude mice bearing MCF7BoM2
Molecules identified in the study miRNA
Methods used in the study qPCR
6
Experiment ID 713
Identified molecule miRNA
Identification method
qPCR   
PubMed ID 34465793    
Organism Homo sapiens
Experiment description Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer
Authors "Wu K, Feng J, Lyu F, Xing F, Sharma S, Liu Y, Wu SY, Zhao D, Tyagi A, Deshpande RP, Pei X, Ruiz MG, Takahashi H, Tsuzuki S, Kimura T, Mo YY, Shiozawa Y, Singh R, Watabe K."
Journal name Nat Commun
Publication year 2021
Sample Breast cancer cells
Sample name Serum - nude mice bearing MCF7BoM2
Molecules identified in the study miRNA
Methods used in the study qPCR
7
Experiment ID 714
Identified molecule miRNA
Identification method
qPCR   
PubMed ID 34465793    
Organism Homo sapiens
Experiment description Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer
Authors "Wu K, Feng J, Lyu F, Xing F, Sharma S, Liu Y, Wu SY, Zhao D, Tyagi A, Deshpande RP, Pei X, Ruiz MG, Takahashi H, Tsuzuki S, Kimura T, Mo YY, Shiozawa Y, Singh R, Watabe K."
Journal name Nat Commun
Publication year 2021
Sample Breast cancer cells
Sample name Primary tumour culture - nude mice bearing T47D
Molecules identified in the study miRNA
Methods used in the study qPCR
8
Experiment ID 715
Identified molecule miRNA
Identification method
qPCR   
PubMed ID 34465793    
Organism Homo sapiens
Experiment description Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer
Authors "Wu K, Feng J, Lyu F, Xing F, Sharma S, Liu Y, Wu SY, Zhao D, Tyagi A, Deshpande RP, Pei X, Ruiz MG, Takahashi H, Tsuzuki S, Kimura T, Mo YY, Shiozawa Y, Singh R, Watabe K."
Journal name Nat Commun
Publication year 2021
Sample Breast cancer cells
Sample name Liver metastatic lesion culture - nude mice bearing T47D
Molecules identified in the study miRNA
Methods used in the study qPCR
9
Experiment ID 716
Identified molecule miRNA
Identification method
qPCR   
PubMed ID 34465793    
Organism Homo sapiens
Experiment description Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer
Authors "Wu K, Feng J, Lyu F, Xing F, Sharma S, Liu Y, Wu SY, Zhao D, Tyagi A, Deshpande RP, Pei X, Ruiz MG, Takahashi H, Tsuzuki S, Kimura T, Mo YY, Shiozawa Y, Singh R, Watabe K."
Journal name Nat Commun
Publication year 2021
Sample Breast cancer cells
Sample name Kidney metastatic lesion culture - nude mice bearing T47D
Molecules identified in the study miRNA
Methods used in the study qPCR
10
Experiment ID 717
Identified molecule miRNA
Identification method
qPCR   
PubMed ID 34465793    
Organism Homo sapiens
Experiment description Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer
Authors "Wu K, Feng J, Lyu F, Xing F, Sharma S, Liu Y, Wu SY, Zhao D, Tyagi A, Deshpande RP, Pei X, Ruiz MG, Takahashi H, Tsuzuki S, Kimura T, Mo YY, Shiozawa Y, Singh R, Watabe K."
Journal name Nat Commun
Publication year 2021
Sample Breast cancer cells
Sample name Lung metastatic lesion culture - nude mice bearing T47D
Molecules identified in the study miRNA
Methods used in the study qPCR
11
Experiment ID 718
Identified molecule miRNA
Identification method
qPCR   
PubMed ID 34465793    
Organism Homo sapiens
Experiment description Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer
Authors "Wu K, Feng J, Lyu F, Xing F, Sharma S, Liu Y, Wu SY, Zhao D, Tyagi A, Deshpande RP, Pei X, Ruiz MG, Takahashi H, Tsuzuki S, Kimura T, Mo YY, Shiozawa Y, Singh R, Watabe K."
Journal name Nat Commun
Publication year 2021
Sample Breast cancer cells
Sample name Bone metastatic lesion culture - nude mice bearing T47D
Molecules identified in the study miRNA
Methods used in the study qPCR
12
Experiment ID 117
Identified molecule miRNA
Identification method
Human miRNA Microarray Kit   
PubMed ID 21505438    
Organism Homo sapiens
Experiment description Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells.
Authors "Mittelbrunn M, Gutierrez-Vázquez C, Villarroya-Beltri C, González S, Sánchez-Cabo F, González MÁ, Bernad A, Sánchez-Madrid F."
Journal name NATCOM
Publication year 2011
Sample Dendritic cells
Sample name Dendritic cells
Molecules identified in the study Protein
miRNA
Methods used in the study Mass spectrometry
Microarray
13
Experiment ID 45
Identified molecule miRNA
Identification method
467microRNA Array   
PubMed ID 18589210    
Organism Homo sapiens
Experiment description MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer.
Authors "Taylor DD, Gercel-Taylor C"
Journal name GO
Publication year 2008
Sample Serum
Sample name Serum - Papillary adenocarcinoma of ovary
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
467microRNA Array
14
Experiment ID 703
Identified molecule miRNA
Identification method
qPCR   
PubMed ID 34465793    
Organism Homo sapiens
Experiment description Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer
Authors "Wu K, Feng J, Lyu F, Xing F, Sharma S, Liu Y, Wu SY, Zhao D, Tyagi A, Deshpande RP, Pei X, Ruiz MG, Takahashi H, Tsuzuki S, Kimura T, Mo YY, Shiozawa Y, Singh R, Watabe K."
Journal name Nat Commun
Publication year 2021
Sample Serum
Sample name Serum - ER-positive breast cancer patients
Molecules identified in the study miRNA
Methods used in the study qPCR
15
Experiment ID 704
Identified molecule miRNA
Identification method
qPCR   
PubMed ID 34465793    
Organism Homo sapiens
Experiment description Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer
Authors "Wu K, Feng J, Lyu F, Xing F, Sharma S, Liu Y, Wu SY, Zhao D, Tyagi A, Deshpande RP, Pei X, Ruiz MG, Takahashi H, Tsuzuki S, Kimura T, Mo YY, Shiozawa Y, Singh R, Watabe K."
Journal name Nat Commun
Publication year 2021
Sample Serum
Sample name Serum - Her2-positive breast cancer patients
Molecules identified in the study miRNA
Methods used in the study qPCR
16
Experiment ID 705
Identified molecule miRNA
Identification method
qPCR   
PubMed ID 34465793    
Organism Homo sapiens
Experiment description Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer
Authors "Wu K, Feng J, Lyu F, Xing F, Sharma S, Liu Y, Wu SY, Zhao D, Tyagi A, Deshpande RP, Pei X, Ruiz MG, Takahashi H, Tsuzuki S, Kimura T, Mo YY, Shiozawa Y, Singh R, Watabe K."
Journal name Nat Commun
Publication year 2021
Sample Serum
Sample name Serum - recurrence-free (10 year) TNBC patients
Molecules identified in the study miRNA
Methods used in the study qPCR
17
Experiment ID 706
Identified molecule miRNA
Identification method
qPCR   
PubMed ID 34465793    
Organism Homo sapiens
Experiment description Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer
Authors "Wu K, Feng J, Lyu F, Xing F, Sharma S, Liu Y, Wu SY, Zhao D, Tyagi A, Deshpande RP, Pei X, Ruiz MG, Takahashi H, Tsuzuki S, Kimura T, Mo YY, Shiozawa Y, Singh R, Watabe K."
Journal name Nat Commun
Publication year 2021
Sample Serum
Sample name Serum - ER-negative breast cancer patients with visceral metastasis
Molecules identified in the study miRNA
Methods used in the study qPCR
18
Experiment ID 707
Identified molecule miRNA
Identification method
qPCR   
PubMed ID 34465793    
Organism Homo sapiens
Experiment description Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer
Authors "Wu K, Feng J, Lyu F, Xing F, Sharma S, Liu Y, Wu SY, Zhao D, Tyagi A, Deshpande RP, Pei X, Ruiz MG, Takahashi H, Tsuzuki S, Kimura T, Mo YY, Shiozawa Y, Singh R, Watabe K."
Journal name Nat Commun
Publication year 2021
Sample Serum
Sample name Serum - ER-negative breast cancer patients with bone metastasis
Molecules identified in the study miRNA
Methods used in the study qPCR
19
Experiment ID 708
Identified molecule miRNA
Identification method
qPCR   
PubMed ID 34465793    
Organism Homo sapiens
Experiment description Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer
Authors "Wu K, Feng J, Lyu F, Xing F, Sharma S, Liu Y, Wu SY, Zhao D, Tyagi A, Deshpande RP, Pei X, Ruiz MG, Takahashi H, Tsuzuki S, Kimura T, Mo YY, Shiozawa Y, Singh R, Watabe K."
Journal name Nat Commun
Publication year 2021
Sample Serum
Sample name Serum - ER-positive breast cancer patients with visceral metastasis
Molecules identified in the study miRNA
Methods used in the study qPCR
20
Experiment ID 709
Identified molecule miRNA
Identification method
qPCR   
PubMed ID 34465793    
Organism Homo sapiens
Experiment description Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer
Authors "Wu K, Feng J, Lyu F, Xing F, Sharma S, Liu Y, Wu SY, Zhao D, Tyagi A, Deshpande RP, Pei X, Ruiz MG, Takahashi H, Tsuzuki S, Kimura T, Mo YY, Shiozawa Y, Singh R, Watabe K."
Journal name Nat Commun
Publication year 2021
Sample Serum
Sample name Serum - ER-positive breast cancer patients with bone metastasis
Molecules identified in the study miRNA
Methods used in the study qPCR
21
Experiment ID 115
Identified molecule miRNA
Identification method
Human miRNA Microarray Kit   
PubMed ID 21505438    
Organism Homo sapiens
Experiment description Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells.
Authors "Mittelbrunn M, Gutierrez-Vázquez C, Villarroya-Beltri C, González S, Sánchez-Cabo F, González MÁ, Bernad A, Sánchez-Madrid F."
Journal name NATCOM
Publication year 2011
Sample T cells
Sample name J77
Molecules identified in the study Protein
miRNA
Methods used in the study Mass spectrometry
Microarray