 miRNA description for miR-221 |
| miRNA accession |
miR-221 |
| Species |
Homo sapiens |
| miR-221 identified in sEVs derived from the following tissue/cell type |
|
Dendritic cells
|
21505438
|
|
Endothelial cells
|
26027894
|
|
Mesenchymal stem cells
|
25669974
|
|
Serum
|
18589210
|
|
T cells
|
21505438
|
| Experiment description of studies that identified miR-221 in sEVs |
| 1 |
| Experiment ID |
117 |
| Identified molecule |
miRNA
|
| Identification method |
| Human miRNA Microarray Kit |
|
|
| PubMed ID |
21505438
|
| Organism |
Homo sapiens |
| Experiment description |
Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells. |
| Authors |
"Mittelbrunn M, Gutierrez-Vázquez C, Villarroya-Beltri C, González S, Sánchez-Cabo F, González MÃÂ, Bernad A, Sánchez-Madrid F." |
| Journal name |
NATCOM
|
| Publication year |
2011 |
| Sample |
Dendritic cells |
| Sample name |
Dendritic cells |
| Molecules identified in the study |
Protein
miRNA |
| Methods used in the study |
Mass spectrometry
Microarray |
|
|
| 2 |
| Experiment ID |
226 |
| Identified molecule |
miRNA
|
| Identification method |
| Small RNA sequencing (Illumina HiSeq 2000 (Solexa) |
|
|
| PubMed ID |
26027894
|
| Organism |
Homo sapiens |
| Experiment description |
"Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting" |
| Authors |
"Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar" |
| Journal name |
Journal of Extracellular Vesicles
|
| Publication year |
2015 |
| Sample |
Endothelial cells |
| Sample name |
HMEC-1 |
| Molecules identified in the study |
miRNA
Protein
snoRNA
lncRNA
yRNA
snRNA
mRNA
ncRNA
mtRNA
vtRNA
scaRNA
lincRNA |
| Methods used in the study |
Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
Western blotting |
|
|
| 3 |
| Experiment ID |
261 |
| Identified molecule |
miRNA
|
| Identification method |
Next generation sequencing
RT-PCR |
|
|
| PubMed ID |
25669974
|
| Organism |
Homo sapiens |
| Experiment description |
"Extracellular vesicles from bone marrow mesenchymal stem/stromal cells transport tumor regulatory microRNA, proteins,and metabolites" |
| Authors |
"Krishna C. Vallabhaneni1, Patrice Penfornis, Santosh Dhule, Francois Guillonneau, Kristen V. Adams, Yin Yuan Mo, Rui Xu, Yiming Liu, Kounosuke Watabe, Mohan C. Vemuri and Radhika Pochampally" |
| Journal name |
Oncotarget
|
| Publication year |
2014 |
| Sample |
Mesenchymal stem cells |
| Sample name |
hMSCs |
| Molecules identified in the study |
Protein
miRNA
Lipids
Metabolites |
| Methods used in the study |
Western blotting
Mass spectrometry
RT-PCR
Sequencing |
|
|
| 4 |
| Experiment ID |
45 |
| Identified molecule |
miRNA
|
| Identification method |
|
| PubMed ID |
18589210
|
| Organism |
Homo sapiens |
| Experiment description |
MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer. |
| Authors |
"Taylor DD, Gercel-Taylor C" |
| Journal name |
GO
|
| Publication year |
2008 |
| Sample |
Serum |
| Sample name |
Serum - Papillary adenocarcinoma of ovary |
| Molecules identified in the study |
Protein
miRNA |
| Methods used in the study |
Western blotting
467microRNA Array |
|
|
| 5 |
| Experiment ID |
115 |
| Identified molecule |
miRNA
|
| Identification method |
| Human miRNA Microarray Kit |
|
|
| PubMed ID |
21505438
|
| Organism |
Homo sapiens |
| Experiment description |
Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells. |
| Authors |
"Mittelbrunn M, Gutierrez-Vázquez C, Villarroya-Beltri C, González S, Sánchez-Cabo F, González MÃÂ, Bernad A, Sánchez-Madrid F." |
| Journal name |
NATCOM
|
| Publication year |
2011 |
| Sample |
T cells |
| Sample name |
J77 |
| Molecules identified in the study |
Protein
miRNA |
| Methods used in the study |
Mass spectrometry
Microarray |
|
|