miRNA description for miR-222
miRNA accession miR-222
Species Homo sapiens
 miR-222 identified in sEVs derived from the following tissue/cell type
Breast cancer cells 33752173    
Breast cancer cells 33752173    
Breast cancer cells 33752173    
Breast cancer cells 33752173    
Dendritic cells 21505438    
Endothelial cells 26027894    
Plasma 33752173    
Plasma 33752173    
Serum 18589210    
T cells 21505438    
 Experiment description of studies that identified miR-222 in sEVs
1
Experiment ID 373
Identified molecule miRNA
Identification method
RT-PCR   
PubMed ID 33752173    
Organism Homo sapiens
Experiment description Exosomal miR-222 from adriamycin-resistant MCF-7 breast cancer cells promote macrophages M2 polarization via PTEN/Akt to induce tumor progression
Authors "Chen WX, Wang DD, Zhu B, Zhu YZ, Zheng L, Feng ZQ, Qin XH."
Journal name Aging
Publication year 2021
Sample Breast cancer cells
Sample name MCF7 - Adriamycin-resistant
Molecules identified in the study miRNA
Methods used in the study RT-PCR
2
Experiment ID 374
Identified molecule miRNA
Identification method
RT-PCR   
PubMed ID 33752173    
Organism Homo sapiens
Experiment description Exosomal miR-222 from adriamycin-resistant MCF-7 breast cancer cells promote macrophages M2 polarization via PTEN/Akt to induce tumor progression
Authors "Chen WX, Wang DD, Zhu B, Zhu YZ, Zheng L, Feng ZQ, Qin XH."
Journal name Aging
Publication year 2021
Sample Breast cancer cells
Sample name MCF7 - Adriamycin-sensitive
Molecules identified in the study miRNA
Methods used in the study RT-PCR
3
Experiment ID 375
Identified molecule miRNA
Identification method
RT-PCR   
PubMed ID 33752173    
Organism Homo sapiens
Experiment description Exosomal miR-222 from adriamycin-resistant MCF-7 breast cancer cells promote macrophages M2 polarization via PTEN/Akt to induce tumor progression
Authors "Chen WX, Wang DD, Zhu B, Zhu YZ, Zheng L, Feng ZQ, Qin XH."
Journal name Aging
Publication year 2021
Sample Breast cancer cells
Sample name Breast cancer tissue from patients - chemoresistant
Molecules identified in the study miRNA
Methods used in the study RT-PCR
4
Experiment ID 376
Identified molecule miRNA
Identification method
RT-PCR   
PubMed ID 33752173    
Organism Homo sapiens
Experiment description Exosomal miR-222 from adriamycin-resistant MCF-7 breast cancer cells promote macrophages M2 polarization via PTEN/Akt to induce tumor progression
Authors "Chen WX, Wang DD, Zhu B, Zhu YZ, Zheng L, Feng ZQ, Qin XH."
Journal name Aging
Publication year 2021
Sample Breast cancer cells
Sample name Brease cancer tissue from - chemosensitive
Molecules identified in the study miRNA
Methods used in the study RT-PCR
5
Experiment ID 117
Identified molecule miRNA
Identification method
Human miRNA Microarray Kit   
PubMed ID 21505438    
Organism Homo sapiens
Experiment description Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells.
Authors "Mittelbrunn M, Gutierrez-Vázquez C, Villarroya-Beltri C, González S, Sánchez-Cabo F, González MÁ, Bernad A, Sánchez-Madrid F."
Journal name NATCOM
Publication year 2011
Sample Dendritic cells
Sample name Dendritic cells
Molecules identified in the study Protein
miRNA
Methods used in the study Mass spectrometry
Microarray
6
Experiment ID 226
Identified molecule miRNA
Identification method
Small RNA sequencing (Illumina HiSeq 2000 (Solexa)   
PubMed ID 26027894    
Organism Homo sapiens
Experiment description "Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting"
Authors "Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar"
Journal name Journal of Extracellular Vesicles
Publication year 2015
Sample Endothelial cells
Sample name HMEC-1
Molecules identified in the study miRNA
Protein
snoRNA
lncRNA
yRNA
snRNA
mRNA
ncRNA
mtRNA
vtRNA
scaRNA
lincRNA
Methods used in the study Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
Western blotting
7
Experiment ID 377
Identified molecule miRNA
Identification method
RT-PCR   
PubMed ID 33752173    
Organism Homo sapiens
Experiment description Exosomal miR-222 from adriamycin-resistant MCF-7 breast cancer cells promote macrophages M2 polarization via PTEN/Akt to induce tumor progression
Authors "Chen WX, Wang DD, Zhu B, Zhu YZ, Zheng L, Feng ZQ, Qin XH."
Journal name Aging
Publication year 2021
Sample Plasma
Sample name Breast cancer patients - chemoresistant
Molecules identified in the study miRNA
Methods used in the study RT-PCR
8
Experiment ID 378
Identified molecule miRNA
Identification method
RT-PCR   
PubMed ID 33752173    
Organism Homo sapiens
Experiment description Exosomal miR-222 from adriamycin-resistant MCF-7 breast cancer cells promote macrophages M2 polarization via PTEN/Akt to induce tumor progression
Authors "Chen WX, Wang DD, Zhu B, Zhu YZ, Zheng L, Feng ZQ, Qin XH."
Journal name Aging
Publication year 2021
Sample Plasma
Sample name Breast cancer patients - chemosensitive
Molecules identified in the study miRNA
Methods used in the study RT-PCR
9
Experiment ID 45
Identified molecule miRNA
Identification method
467microRNA Array   
PubMed ID 18589210    
Organism Homo sapiens
Experiment description MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer.
Authors "Taylor DD, Gercel-Taylor C"
Journal name GO
Publication year 2008
Sample Serum
Sample name Serum - Papillary adenocarcinoma of ovary
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
467microRNA Array
10
Experiment ID 115
Identified molecule miRNA
Identification method
Human miRNA Microarray Kit   
PubMed ID 21505438    
Organism Homo sapiens
Experiment description Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells.
Authors "Mittelbrunn M, Gutierrez-Vázquez C, Villarroya-Beltri C, González S, Sánchez-Cabo F, González MÁ, Bernad A, Sánchez-Madrid F."
Journal name NATCOM
Publication year 2011
Sample T cells
Sample name J77
Molecules identified in the study Protein
miRNA
Methods used in the study Mass spectrometry
Microarray