Gene description for RBM14-RBM4
Gene name RBM14-RBM4 readthrough
Gene symbol RBM14-RBM4
Other names/aliases COAZ
Species Homo sapiens
 Database cross references - RBM14-RBM4
ExoCarta ExoCarta_100526737
Vesiclepedia VP_100526737
Entrez Gene 100526737
HGNC 38840
UniProt Q96PK6  
 RBM14-RBM4 identified in sEVs derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
Hepatocellular carcinoma cells 26054723    
Thymus 23844026    
 Gene ontology annotations for RBM14-RBM4
 Experiment description of studies that identified RBM14-RBM4 in sEVs
1
Experiment ID 235
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
2
Experiment ID 236
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name MHCC97L
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
3
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for RBM14-RBM4
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 H2AFJ 55766
Affinity Capture-MS Homo sapiens
2 SENP3 26168
Affinity Capture-MS Homo sapiens
3 NPRL2  
Affinity Capture-MS Homo sapiens
4 SERPINB13 5275
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
5 LAMP2 3920
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
6 RPS2P32  
Affinity Capture-MS Homo sapiens
7 ANKRD39  
Affinity Capture-MS Homo sapiens
8 GRB7 2886
Affinity Capture-MS Homo sapiens
9 NDC80 10403
Affinity Capture-MS Homo sapiens
10 SURF2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
11 GSPT2 23708
Affinity Capture-MS Homo sapiens
12 HSD17B14  
Affinity Capture-MS Homo sapiens
13 NAA11 84779
Affinity Capture-MS Homo sapiens
14 ZSCAN21  
Affinity Capture-MS Homo sapiens
15 F9 2158
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
16 BCL2L14  
Affinity Capture-MS Homo sapiens
17 OBSL1 23363
Affinity Capture-MS Homo sapiens
18 CRCP  
Affinity Capture-MS Homo sapiens
19 C3orf52  
Affinity Capture-MS Homo sapiens
20 EXOSC4 54512
Affinity Capture-MS Homo sapiens
21 DGCR2 9993
Affinity Capture-MS Homo sapiens
22 LIPG 9388
Affinity Capture-MS Homo sapiens
23 IL17RA 23765
Affinity Capture-MS Homo sapiens
24 MTMR10 54893
Affinity Capture-MS Homo sapiens
25 FAF2 23197
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
26 LOXL2 4017
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
27 WFDC1  
Affinity Capture-MS Homo sapiens
28 RAB1B 81876
Affinity Capture-MS Homo sapiens
29 CAMK2A 815
Affinity Capture-MS Homo sapiens
30 GADL1  
Affinity Capture-MS Homo sapiens
31 MANSC1 54682
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
32 CEP41  
Affinity Capture-MS Homo sapiens
33 CTBP1 1487
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
34 RPS10 6204
Affinity Capture-MS Homo sapiens
35 DNAH17 8632
Affinity Capture-MS Homo sapiens
36 IL2RA  
Affinity Capture-MS Homo sapiens
37 MEF2BNB  
Affinity Capture-MS Homo sapiens
38 C3orf49  
Affinity Capture-MS Homo sapiens
39 TMEM206 55248
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
40 CDH12  
Affinity Capture-MS Homo sapiens
41 LOC388882  
Affinity Capture-MS Homo sapiens
42 NMNAT2  
Affinity Capture-MS Homo sapiens
43 ZNF747  
Affinity Capture-MS Homo sapiens
44 MAGEA8  
Affinity Capture-MS Homo sapiens
45 RBM39 9584
Co-fractionation Homo sapiens
46 VPS4B 9525
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
47 MUS81  
Affinity Capture-MS Homo sapiens
48 PSENEN  
Affinity Capture-MS Homo sapiens
49 CPA2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
50 RLIM 51132
Affinity Capture-MS Homo sapiens
51 PTH2R  
Affinity Capture-MS Homo sapiens
52 GPR12  
Affinity Capture-MS Homo sapiens
53 CLEC4A  
Affinity Capture-MS Homo sapiens
54 HTR2C  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
55 WDR37 22884
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
56 TMEM74  
Affinity Capture-MS Homo sapiens
57 SUZ12  
Affinity Capture-MS Homo sapiens
58 CCDC85A  
Affinity Capture-MS Homo sapiens
59 VPS37A 137492
Affinity Capture-MS Homo sapiens
60 DNAI2  
Affinity Capture-MS Homo sapiens
61 SLC25A18  
Affinity Capture-MS Homo sapiens
62 PHC1  
Affinity Capture-MS Homo sapiens
63 PRSS8 5652
Affinity Capture-MS Homo sapiens
64 JUNB  
Affinity Capture-MS Homo sapiens
65 CUL7 9820
Affinity Capture-MS Homo sapiens
66 FAM107B 83641
Affinity Capture-MS Homo sapiens
67 KRAS 3845
Synthetic Lethality Homo sapiens
68 GRAMD1B  
Affinity Capture-MS Homo sapiens
69 NAA10 8260
Affinity Capture-MS Homo sapiens
70 GCNT3 9245
Affinity Capture-MS Homo sapiens
71 PPT1 5538
Affinity Capture-MS Homo sapiens
72 TMEM51 55092
Affinity Capture-MS Homo sapiens
73 WDR34 89891
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
74 SIRT6  
Affinity Capture-MS Homo sapiens
75 WDR4 10785
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
76 AP1G2 8906
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
77 CXCL14  
Affinity Capture-MS Homo sapiens
78 APBB3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
79 DDX58 23586
Affinity Capture-RNA Homo sapiens
80 AARSD1 80755
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
81 C20orf197  
Affinity Capture-MS Homo sapiens
82 CDK13 8621
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
83 POMK  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
84 KLHL22 84861
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
85 KCTD17 79734
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
86 SRMS  
Affinity Capture-MS Homo sapiens
87 EDN3  
Affinity Capture-MS Homo sapiens
88 NOL9 79707
Affinity Capture-MS Homo sapiens
89 LURAP1  
Affinity Capture-MS Homo sapiens
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