Gene description for NAA11
Gene name N(alpha)-acetyltransferase 11, NatA catalytic subunit
Gene symbol NAA11
Other names/aliases ARD1B
ARD2
hARD2
Species Homo sapiens
 Database cross references - NAA11
ExoCarta ExoCarta_84779
Vesiclepedia VP_84779
Entrez Gene 84779
HGNC 28125
UniProt Q9BSU3  
 NAA11 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for NAA11
Molecular Function
    peptide alpha-N-acetyltransferase activity GO:0004596 IDA
    protein binding GO:0005515 IPI
    peptide-alanine-alpha-N-acetyltransferase activity GO:0008999 IEA
    peptide-serine-alpha-N-acetyltransferase activity GO:1990189 IBA
    peptide-glutamate-alpha-N-acetyltransferase activity GO:1990190 IBA
Biological Process
    N-terminal protein amino acid acetylation GO:0006474 IDA
Subcellular Localization
    nucleoplasm GO:0005654 IDA
    cytoplasm GO:0005737 NAS
    Golgi apparatus GO:0005794 IDA
    centrosome GO:0005813 IDA
    cytosol GO:0005829 IDA
    NatA complex GO:0031415 IBA
    NatA complex GO:0031415 IDA
    NatA complex GO:0031415 IPI
 Experiment description of studies that identified NAA11 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for NAA11
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 DSN1 79980
Affinity Capture-MS Homo sapiens
2 CDCA5  
Two-hybrid Homo sapiens
3 N4BP2L2 10443
Affinity Capture-MS Homo sapiens
4 CDC25A  
Two-hybrid Homo sapiens
5 ZNF202  
Two-hybrid Homo sapiens
6 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
7 ZNHIT6 54680
Affinity Capture-MS Homo sapiens
8 NDRG1 10397
Affinity Capture-MS Homo sapiens
9 N4BP2  
Affinity Capture-MS Homo sapiens
10 DVL2 1856
Affinity Capture-MS Homo sapiens
11 CREBRF  
Two-hybrid Homo sapiens
12 DSCC1  
Affinity Capture-MS Homo sapiens
13 RIN2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
14 ACTA2 59
Affinity Capture-MS Homo sapiens
15 ANAPC5 51433
Affinity Capture-MS Homo sapiens
16 NAA15 80155
Affinity Capture-MS Homo sapiens
17 HYPK 25764
Affinity Capture-MS Homo sapiens
18 NAA16 79612
Affinity Capture-MS Homo sapiens
19 NAA50 80218
Affinity Capture-MS Homo sapiens
20 TNPO3 23534
Affinity Capture-MS Homo sapiens
21 NDUFAF7  
Affinity Capture-MS Homo sapiens
22 NARFL 64428
Affinity Capture-MS Homo sapiens
23 MAP1B 4131
Cross-Linking-MS (XL-MS) Homo sapiens
24 TBC1D2B 23102
Affinity Capture-MS Homo sapiens
25 NEFM 4741
Cross-Linking-MS (XL-MS) Homo sapiens
26 FMNL3 91010
Affinity Capture-MS Homo sapiens
27 MARC1  
Two-hybrid Homo sapiens
28 PEX1 5189
Affinity Capture-MS Homo sapiens
29 AP2M1 1173
Two-hybrid Homo sapiens
30 DUS3L 56931
Affinity Capture-MS Homo sapiens
31 OFD1 8481
Affinity Capture-MS Homo sapiens
32 PLEKHG4  
Affinity Capture-MS Homo sapiens
33 DDX11 1663
Affinity Capture-MS Homo sapiens
34 PI4K2B 55300
Affinity Capture-MS Homo sapiens
35 BRCA2 675
Affinity Capture-MS Homo sapiens
36 CAMK2B 816
Affinity Capture-MS Homo sapiens
37 ACOT12  
Two-hybrid Homo sapiens
38 CELSR2  
Affinity Capture-MS Homo sapiens
39 APAF1 317
Affinity Capture-MS Homo sapiens
40 MTO1  
Affinity Capture-MS Homo sapiens
41 RBM14-RBM4 100526737
Affinity Capture-MS Homo sapiens
42 EHMT2 10919
Two-hybrid Homo sapiens
43 CASC5  
Affinity Capture-MS Homo sapiens
44 KIF11 3832
Affinity Capture-MS Homo sapiens
45 PDE4DIP 9659
Affinity Capture-MS Homo sapiens
46 MTMR1 8776
Affinity Capture-MS Homo sapiens
47 KRAS 3845
Synthetic Lethality Homo sapiens
48 ZBTB14  
Two-hybrid Homo sapiens
49 TDP2 51567
Affinity Capture-MS Homo sapiens
50 KIAA1671  
Affinity Capture-MS Homo sapiens
51 CCDC88A 55704
Affinity Capture-MS Homo sapiens
52 DYNC2H1 79659
Affinity Capture-MS Homo sapiens
53 HAUS6  
Affinity Capture-MS Homo sapiens
54 POGK 57645
Affinity Capture-MS Homo sapiens
55 STIL  
Affinity Capture-MS Homo sapiens
56 PRKACB 5567
Affinity Capture-MS Homo sapiens
57 BAALC  
Two-hybrid Homo sapiens
58 NAA10 8260
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which NAA11 is involved
No pathways found





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