Gene description for RBM6
Gene name RNA binding motif protein 6
Gene symbol RBM6
Other names/aliases 3G2
DEF-3
DEF3
HLC-11
NY-LU-12
g16
Species Homo sapiens
 Database cross references - RBM6
ExoCarta ExoCarta_10180
Vesiclepedia VP_10180
Entrez Gene 10180
HGNC 9903
MIM 606886
UniProt P78332  
 RBM6 identified in sEVs derived from the following tissue/cell type
Urine 21595033    
Urine 21595033    
Urine 21595033    
 Gene ontology annotations for RBM6
Molecular Function
    DNA binding GO:0003677 TAS
    RNA binding GO:0003723 HDA
    RNA binding GO:0003723 IBA
    protein binding GO:0005515 IPI
Biological Process
    mRNA splicing, via spliceosome GO:0000398 IBA
    RNA processing GO:0006396 TAS
Subcellular Localization
    nucleus GO:0005634 IBA
 Experiment description of studies that identified RBM6 in sEVs
1
Experiment ID 193
MISEV standards
EM
Biophysical techniques
CD63|CD9
Enriched markers
PHB
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 194
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Patients of basement membrane nephropathy
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
3
Experiment ID 195
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Patients of early IgA nephropathy
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for RBM6
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 HNRNPH1 3187
Affinity Capture-RNA Homo sapiens
2 NCBP1 4686
Affinity Capture-MS Homo sapiens
3 PPP1CB 5500
Affinity Capture-MS Homo sapiens
4 EEF1G 1937
Two-hybrid Homo sapiens
5 CTNNBL1 56259
Affinity Capture-MS Homo sapiens
6 DHX8 1659
Proximity Label-MS Homo sapiens
7 TAS2R42  
Affinity Capture-MS Homo sapiens
8 TMEM45A  
Affinity Capture-MS Homo sapiens
9 DDX23 9416
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
10 PLOD3 8985
Affinity Capture-MS Homo sapiens
11 ASB12  
Affinity Capture-MS Homo sapiens
12 ACER3  
Affinity Capture-MS Homo sapiens
13 TNP2  
Affinity Capture-MS Homo sapiens
14 Fus  
Affinity Capture-MS Mus musculus
15 NAGK 55577
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
16 MECP2 4204
Affinity Capture-MS Homo sapiens
17 SNX27 81609
Affinity Capture-MS Homo sapiens
18 ARHGAP22 58504
Affinity Capture-MS Homo sapiens
19 THOC1 9984
Affinity Capture-MS Homo sapiens
20 FEM1A  
Affinity Capture-MS Homo sapiens
21 RBM14 10432
Affinity Capture-MS Homo sapiens
22 KIF14 9928
Affinity Capture-MS Homo sapiens
23 LSM2 57819
Affinity Capture-MS Homo sapiens
24 AURKA 6790
Affinity Capture-MS Homo sapiens
25 DHX40  
Proximity Label-MS Homo sapiens
26 PRPF8 10594
Affinity Capture-MS Homo sapiens
27 NUP50 10762
Proximity Label-MS Homo sapiens
28 Taf15  
Affinity Capture-MS Mus musculus
29 PNN 5411
Affinity Capture-MS Homo sapiens
30 SNRNP200 23020
Affinity Capture-MS Homo sapiens
31 AKR7L 246181
Affinity Capture-MS Homo sapiens
32 DDX5 1655
Affinity Capture-MS Homo sapiens
33 DTX2 113878
Proximity Label-MS Homo sapiens
34 HECTD1 25831
Affinity Capture-MS Homo sapiens
35 PAK7  
Affinity Capture-MS Homo sapiens
36 HNRNPA3 220988
Affinity Capture-MS Homo sapiens
37 ASB18  
Affinity Capture-MS Homo sapiens
38 ZBTB44  
Affinity Capture-MS Homo sapiens
39 TAF7  
Two-hybrid Homo sapiens
40 MITF  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
41 Cnbp 12785
Two-hybrid Mus musculus
42 ALS2  
Affinity Capture-MS Homo sapiens
43 SIRT7  
Affinity Capture-MS Homo sapiens
44 PLRG1 5356
Affinity Capture-MS Homo sapiens
45 PAPD5 64282
Affinity Capture-MS Homo sapiens
46 HNRNPA1 3178
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
47 FUS 2521
Affinity Capture-MS Homo sapiens
48 SART1 9092
Affinity Capture-MS Homo sapiens
49 NXF1 10482
Affinity Capture-RNA Homo sapiens
50 EFTUD2 9343
Affinity Capture-MS Homo sapiens
51 MYCN  
Affinity Capture-MS Homo sapiens
52 CTCFL  
Affinity Capture-MS Homo sapiens
53 MFAP1  
Affinity Capture-MS Homo sapiens
54 PRPF19 27339
Affinity Capture-MS Homo sapiens
55 ZC3H18  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
56 EMC2 9694
Affinity Capture-MS Homo sapiens
57 TOP1 7150
Affinity Capture-MS Homo sapiens
58 BCAS2 10286
Affinity Capture-MS Homo sapiens
59 MATR3 9782
Affinity Capture-MS Homo sapiens
60 CUL7 9820
Affinity Capture-MS Homo sapiens
61 Junb  
Affinity Capture-MS Mus musculus
62 SF3B3 23450
Two-hybrid Homo sapiens
63 Rpl35 66489
Affinity Capture-MS Mus musculus
64 Ppp1cb 19046
Affinity Capture-MS Mus musculus
65 LMNA 4000
Proximity Label-MS Homo sapiens
66 FTSJ3 117246
Affinity Capture-MS Homo sapiens
67 CEPT1 10390
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
68 ZRANB1 54764
Affinity Capture-MS Homo sapiens
69 FGL1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
70 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
71 SIRT6  
Affinity Capture-MS Homo sapiens
72 ILF3 3609
Affinity Capture-RNA Homo sapiens
73 ERH 2079
Affinity Capture-MS Homo sapiens
74 TCERG1 10915
Affinity Capture-MS Homo sapiens
75 SNRPA 6626
Affinity Capture-MS Homo sapiens
76 EPHX4 253152
Affinity Capture-MS Homo sapiens
77 MAPRE2 10982
Two-hybrid Homo sapiens
78 THRAP3 9967
Affinity Capture-MS Homo sapiens
79 SHMT2 6472
Affinity Capture-RNA Homo sapiens
80 NUP35 129401
Proximity Label-MS Homo sapiens
81 DDX58 23586
Affinity Capture-RNA Homo sapiens
82 MMGT1 93380
Affinity Capture-MS Homo sapiens
83 KLF5  
Proximity Label-MS Homo sapiens
84 SNRNP40 9410
Affinity Capture-MS Homo sapiens
85 Srsf1 110809
Affinity Capture-MS Mus musculus
86 SPCS1 28972
Affinity Capture-MS Homo sapiens
87 GAGE5  
Affinity Capture-MS Homo sapiens
88 CLK2 1196
Two-hybrid Homo sapiens
89 DDX42 11325
Affinity Capture-MS Homo sapiens
90 SNW1 22938
Affinity Capture-MS Homo sapiens
91 KIAA0408  
Affinity Capture-MS Homo sapiens
92 CDC5L 988
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which RBM6 is involved
No pathways found





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