Gene description for NCOA2
Gene name	nuclear receptor coactivator 2
Gene symbol	NCOA2
Other names/aliases	GRIP1 KAT13C NCoA-2 SRC2 TIF2 bHLHe75
Species	Homo sapiens
Database cross references - NCOA2
ExoCarta	ExoCarta_10499
Vesiclepedia	VP_10499
Entrez Gene	10499
HGNC	7669
MIM	601993
UniProt	Q15596
NCOA2 identified in sEVs derived from the following tissue/cell type
Hepatocytes	26054723

Gene ontology annotations for NCOA2

Molecular Function     RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000978 IEA     RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding GO:0001162 IEA     chromatin binding GO:0003682 IEA     transcription coactivator activity GO:0003713 ISS     transcription coactivator activity GO:0003713 NAS     protein binding GO:0005515 IPI     nuclear receptor binding GO:0016922 IBA     nuclear receptor binding GO:0016922 IPI     aryl hydrocarbon receptor binding GO:0017162 IPI     protein domain specific binding GO:0019904 IPI     nuclear receptor coactivator activity GO:0030374 IBA     nuclear receptor coactivator activity GO:0030374 IDA     protein dimerization activity GO:0046983 IEA Biological Process     negative regulation of transcription by RNA polymerase II GO:0000122 IEA     regulation of DNA-templated transcription GO:0006355 NAS     regulation of glucose metabolic process GO:0010906 IEA     regulation of lipid metabolic process GO:0019216 ISS     response to progesterone GO:0032570 IEA     cellular response to hormone stimulus GO:0032870 IBA     circadian regulation of gene expression GO:0032922 ISS     peroxisome proliferator activated receptor signaling pathway GO:0035357 NAS     mRNA transcription by RNA polymerase II GO:0042789 ISS     mRNA transcription by RNA polymerase II GO:0042789 NAS     locomotor rhythm GO:0045475 IEA     positive regulation of transcription by RNA polymerase II GO:0045944 IBA     positive regulation of transcription by RNA polymerase II GO:0045944 IDA     positive regulation of transcription by RNA polymerase II GO:0045944 ISS     regulation of cellular response to insulin stimulus GO:1900076 NAS     cellular response to Thyroglobulin triiodothyronine GO:1904017 IEA     positive regulation of adipose tissue development GO:1904179 NAS Subcellular Localization     chromatin GO:0000785 ISA     nucleus GO:0005634 IBA     nucleus GO:0005634 NAS     nucleoplasm GO:0005654 IDA     nucleoplasm GO:0005654 TAS     transcription regulator complex GO:0005667 IPI     cytoplasm GO:0005737 IEA     nuclear body GO:0016604 IDA     protein-containing complex GO:0032991 IMP     RNA polymerase II transcription regulator complex GO:0090575 EXP     RNA polymerase II transcription regulator complex GO:0090575 NAS