Gene description for FOS
Gene name	FBJ murine osteosarcoma viral oncogene homolog
Gene symbol	FOS
Other names/aliases	AP-1 C-FOS p55
Species	Homo sapiens
Database cross references - FOS
ExoCarta	ExoCarta_2353
Vesiclepedia	VP_2353
Entrez Gene	2353
HGNC	3796
MIM	164810
UniProt	P01100
FOS identified in sEVs derived from the following tissue/cell type
Hepatocytes	26054723

Gene ontology annotations for FOS

Molecular Function     transcription cis-regulatory region binding GO:0000976 IDA     RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000978 IBA     RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000978 IDA     RNA polymerase II core promoter sequence-specific DNA binding GO:0000979 IMP     DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981 IBA     DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981 ISA     transcription coregulator binding GO:0001221 IPI     DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228 IDA     DNA-binding transcription factor activity GO:0003700 IDA     DNA-binding transcription factor activity GO:0003700 IMP     protein binding GO:0005515 IPI     identical protein binding GO:0042802 IPI     protein-containing complex binding GO:0044877 IEA     RNA polymerase II-specific DNA-binding transcription factor binding GO:0061629 IPI     R-SMAD binding GO:0070412 IPI     sequence-specific double-stranded DNA binding GO:1990837 IDA     promoter-specific chromatin binding GO:1990841 IEA Biological Process     conditioned taste aversion GO:0001661 IEA     neural retina development GO:0003407 IEA     regulation of transcription by RNA polymerase II GO:0006357 IBA     regulation of transcription by RNA polymerase II GO:0006357 IDA     regulation of transcription by RNA polymerase II GO:0006357 NAS     transcription by RNA polymerase II GO:0006366 IEA     inflammatory response GO:0006954 TAS     transforming growth factor beta receptor signaling pathway GO:0007179 IDA     female pregnancy GO:0007565 IEA     response to xenobiotic stimulus GO:0009410 IEA     response to light stimulus GO:0009416 IEA     response to gravity GO:0009629 IEA     response to toxic substance GO:0009636 IEA     response to activity GO:0014823 IEA     skeletal muscle cell proliferation GO:0014856 IEA     cerebral cortex development GO:0021987 IEA     neuron differentiation GO:0030182 IEA     osteoclast differentiation GO:0030316 IEA     response to lipopolysaccharide GO:0032496 IEA     response to progesterone GO:0032570 IEA     response to insulin GO:0032868 IEA     cellular response to zinc ion starvation GO:0034224 IEA     cellular response to reactive oxygen species GO:0034614 IDA     response to immobilization stress GO:0035902 IEA     skeletal muscle cell differentiation GO:0035914 IEA     response to muscle stretch GO:0035994 IEA     response to ethanol GO:0045471 IEA     positive regulation of osteoclast differentiation GO:0045672 IEA     positive regulation of DNA-templated transcription GO:0045893 IDA     positive regulation of transcription by RNA polymerase II GO:0045944 IDA     positive regulation of transcription by RNA polymerase II GO:0045944 IGI     positive regulation of transcription by RNA polymerase II GO:0045944 IMP     response to corticosterone GO:0051412 IEA     myoblast proliferation GO:0051450 IEA     response to cAMP GO:0051591 IEA     SMAD protein signal transduction GO:0060395 IDA     cellular response to calcium ion GO:0071277 IEA     cellular response to tumor necrosis factor GO:0071356 IEA     cellular response to epidermal growth factor stimulus GO:0071364 IEA     cellular response to parathyroid hormone stimulus GO:0071374 IEA     cellular response to hypoxia GO:0071456 IEA     medium-term memory GO:0072375 IEA     integrated stress response signaling GO:0140467 NAS     positive regulation of miRNA transcription GO:1902895 IDA     positive regulation of miRNA transcription GO:1902895 ISS     mononuclear cell differentiation GO:1903131 IEA     cellular response to phorbol 13-acetate 12-myristate GO:1904628 IEA     cellular response to prolactin GO:1990646 IEA Subcellular Localization     chromatin GO:0000785 ISA     nucleus GO:0005634 IBA     nucleus GO:0005634 IDA     nucleus GO:0005634 NAS     nucleoplasm GO:0005654 IDA     nucleoplasm GO:0005654 TAS     endoplasmic reticulum GO:0005783 IEA     cytosol GO:0005829 IEA     nuclear matrix GO:0016363 IEA     protein-DNA complex GO:0032993 IMP     transcription factor AP-1 complex GO:0035976 IDA     transcription factor AP-1 complex GO:0035976 IMP     transcription factor AP-1 complex GO:0035976 IPI     RNA polymerase II transcription regulator complex GO:0090575 IPI