Gene description for AQP1
Gene name aquaporin 1 (Colton blood group)
Gene symbol AQP1
Other names/aliases AQP-CHIP
CHIP28
CO
Species Homo sapiens
 Database cross references - AQP1
ExoCarta ExoCarta_358
Vesiclepedia VP_358
Entrez Gene 358
HGNC 633
MIM 107776
UniProt P29972  
 AQP1 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Platelets 25332113    
Platelets 25332113    
Platelets 25332113    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
Urine 15326289    
Urine 19056867    
Urine 22418980    
Urine 22418980    
 Gene ontology annotations for AQP1
Molecular Function
    intracellularly cGMP-activated cation channel activity GO:0005223 IDA
    potassium channel activity GO:0005267 IMP
    water transmembrane transporter activity GO:0005372 IDA
    protein binding GO:0005515 IPI
    ammonium channel activity GO:0008519 IBA
    ammonium channel activity GO:0008519 IDA
    potassium ion transmembrane transporter activity GO:0015079 ISS
    glycerol transmembrane transporter activity GO:0015168 IBA
    glycerol transmembrane transporter activity GO:0015168 IDA
    water channel activity GO:0015250 EXP
    water channel activity GO:0015250 IBA
    water channel activity GO:0015250 IDA
    water channel activity GO:0015250 IMP
    transmembrane transporter activity GO:0022857 IDA
    nitric oxide transmembrane transporter activity GO:0030184 IDA
    carbon dioxide transmembrane transporter activity GO:0035379 IBA
    carbon dioxide transmembrane transporter activity GO:0035379 IDA
    identical protein binding GO:0042802 IPI
    ephrin receptor binding GO:0046875 IEA
    hydrogen peroxide channel activity GO:0140070 IDA
Biological Process
    renal water homeostasis GO:0003091 TAS
    glomerular filtration GO:0003094 IEA
    renal water transport GO:0003097 IBA
    renal water transport GO:0003097 IDA
    potassium ion transport GO:0006813 ISS
    water transport GO:0006833 IDA
    water transport GO:0006833 IMP
    cell volume homeostasis GO:0006884 IMP
    hyperosmotic response GO:0006972 IBA
    intracellular water homeostasis GO:0009992 IDA
    fibroblast migration GO:0010761 IEA
    positive regulation of fibroblast migration GO:0010763 IEA
    carbon dioxide transport GO:0015670 IDA
    glycerol transmembrane transport GO:0015793 IDA
    sensory perception of pain GO:0019233 IEA
    cellular homeostasis GO:0019725 IDA
    cGMP-mediated signaling GO:0019934 IDA
    lateral ventricle development GO:0021670 IEP
    pancreatic juice secretion GO:0030157 IEP
    nitric oxide transport GO:0030185 IDA
    establishment or maintenance of actin cytoskeleton polarity GO:0030950 IMP
    cerebrospinal fluid secretion GO:0033326 IEP
    secretory granule organization GO:0033363 IEA
    cellular response to UV GO:0034644 IDA
    transepithelial water transport GO:0035377 IDA
    carbon dioxide transmembrane transport GO:0035378 IBA
    carbon dioxide transmembrane transport GO:0035378 IDA
    wound healing GO:0042060 IEA
    odontogenesis GO:0042476 IEP
    negative regulation of apoptotic process GO:0043066 IDA
    lipid digestion GO:0044241 IEA
    positive regulation of angiogenesis GO:0045766 IMP
    positive regulation of saliva secretion GO:0046878 IMP
    positive regulation of fibroblast proliferation GO:0048146 IDA
    camera-type eye morphogenesis GO:0048593 IEA
    defense response to Gram-negative bacterium GO:0050829 IMP
    multicellular organismal-level water homeostasis GO:0050891 IEP
    corticotropin secretion GO:0051458 IEA
    establishment of localization in cell GO:0051649 IEA
    renal water absorption GO:0070295 IEA
    cellular response to hydrogen peroxide GO:0070301 IDA
    cellular response to mechanical stimulus GO:0071260 IDA
    cellular response to copper ion GO:0071280 IDA
    cellular response to mercury ion GO:0071288 IDA
    cellular response to retinoic acid GO:0071300 IDA
    cellular response to cAMP GO:0071320 IDA
    cellular response to cAMP GO:0071320 IEP
    cellular response to hypoxia GO:0071456 IDA
    cellular response to salt stress GO:0071472 IDA
    cellular hyperosmotic response GO:0071474 IMP
    cellular response to dexamethasone stimulus GO:0071549 IDA
    cellular response to nitric oxide GO:0071732 IDA
    potassium ion transmembrane transport GO:0071805 IEA
    metanephric descending thin limb development GO:0072220 IEA
    metanephric proximal straight tubule development GO:0072230 IEA
    metanephric proximal convoluted tubule segment 2 development GO:0072232 IEA
    metanephric glomerulus vasculature development GO:0072239 IEA
    ammonium transmembrane transport GO:0072488 IDA
    hydrogen peroxide transmembrane transport GO:0080170 IEA
    negative regulation of cysteine-type endopeptidase activity GO:2000117 IMP
Subcellular Localization
    nucleus GO:0005634 IDA
    cytoplasm GO:0005737 IDA
    plasma membrane GO:0005886 IDA
    plasma membrane GO:0005886 IDA
    plasma membrane GO:0005886 TAS
    brush border GO:0005903 IDA
    basal plasma membrane GO:0009925 IDA
    basolateral plasma membrane GO:0016323 IDA
    apical plasma membrane GO:0016324 IDA
    axon GO:0030424 IEA
    brush border membrane GO:0031526 IDA
    nuclear membrane GO:0031965 IDA
    sarcolemma GO:0042383 IDA
    apical part of cell GO:0045177 IDA
    extracellular exosome GO:0070062 HDA
    extracellular exosome GO:0070062 IDA
    ankyrin-1 complex GO:0170014 IDA
 Experiment description of studies that identified AQP1 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
6
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
7
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 231
MISEV standards
✘ Biophysical techniques
✔
Alix|CD63|CD9
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Western blotting
Mass spectrometry
9
Experiment ID 232
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
10
Experiment ID 233
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
11
Experiment ID 834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
13
Experiment ID 13
MISEV standards
✔
IEM
Biophysical techniques
✔
Alix|RAB4|RAB5B|RAB11|TSG101|CD9|AQP2|AQP1
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 15326289    
Organism Homo sapiens
Experiment description Identification and proteomic profiling of exosomes in human urine.
Authors "Pisitkun T, Shen RF, Knepper MA"
Journal name PNAS
Publication year 2004
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LCQ DECA XP]
Western blotting
14
Experiment ID 63
MISEV standards
✘ Biophysical techniques
✔
AQP2
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors "Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
15
Experiment ID 196
MISEV standards
✔
EM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22418980    
Organism Homo sapiens
Experiment description A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.
Authors "Raj DA, Fiume I, Capasso G, Pocsfalvi G."
Journal name Kidney Int
Publication year 2012
Sample Urine
Sample name Urine - Normal high density
Isolation/purification methods Differential centrifugation
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
16
Experiment ID 197
MISEV standards
✔
EM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22418980    
Organism Homo sapiens
Experiment description A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.
Authors "Raj DA, Fiume I, Capasso G, Pocsfalvi G."
Journal name Kidney Int
Publication year 2012
Sample Urine
Sample name Urine - Normal low density
Isolation/purification methods Differential centrifugation
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for AQP1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SIAH1  
Two-hybrid Homo sapiens
2 KRT37 8688
Two-hybrid Homo sapiens
3 KHDRBS3  
Two-hybrid Homo sapiens
4 ZNF16  
Two-hybrid Homo sapiens
5 RNF122  
Two-hybrid Homo sapiens
6 SPRED2 200734
Two-hybrid Homo sapiens
7 CCDC36  
Two-hybrid Homo sapiens
8 NOTCH2NL 388677
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
9 BEGAIN  
Two-hybrid Homo sapiens
10 KIAA1958  
Two-hybrid Homo sapiens
11 REL 5966
Two-hybrid Homo sapiens
12 SIVA1  
Two-hybrid Homo sapiens
13 MDFI  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
14 ZNF398  
Two-hybrid Homo sapiens
15 IL21R  
Two-hybrid Homo sapiens
16 KRTAP4-12  
Two-hybrid Homo sapiens
17 TMPRSS2 7113
Two-hybrid Homo sapiens
18 AMOT 154796
Two-hybrid Homo sapiens
19 KRT40  
Two-hybrid Homo sapiens
20 MUC1 4582
Two-hybrid Homo sapiens
21 KRTAP4-2  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
22 FOS 2353
Two-hybrid Homo sapiens
23 MTUS2 23281
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
24 KRT31 3881
Two-hybrid Homo sapiens
25 MID2 11043
Two-hybrid Homo sapiens
26 RGS20 8601
Two-hybrid Homo sapiens
27 FSD2 123722
Two-hybrid Homo sapiens
28 CCNDBP1 23582
Two-hybrid Homo sapiens
29 GPX8 493869
Two-hybrid Homo sapiens
30 CRTAC1  
Two-hybrid Homo sapiens
31 SSMEM1  
Two-hybrid Homo sapiens
32 LCE1A  
Two-hybrid Homo sapiens
33 IFT20 90410
Two-hybrid Homo sapiens
34 KRTAP4-4  
Two-hybrid Homo sapiens
35 TRIM41 90933
Two-hybrid Homo sapiens
36 RGS17  
Two-hybrid Homo sapiens
37 IKZF2 22807
Two-hybrid Homo sapiens
38 AQP1 358
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
39 TRIM7  
Two-hybrid Homo sapiens
40 TRIM42  
Two-hybrid Homo sapiens
41 CSRNP1  
Two-hybrid Homo sapiens
42 GOLGA2 2801
Two-hybrid Homo sapiens
43 COMP 1311
Two-hybrid Homo sapiens
44 SLC39A2  
Two-hybrid Homo sapiens
45 SPDYA  
Two-hybrid Homo sapiens
46 EVI2B 2124
Two-hybrid Homo sapiens
47 CYSRT1 375791
Two-hybrid Homo sapiens
48 SLC15A2 6565
Two-hybrid Homo sapiens
49 RNF166  
Affinity Capture-MS Homo sapiens
50 KRTAP6-2  
Two-hybrid Homo sapiens
51 TMEM45B 120224
Two-hybrid Homo sapiens
52 CREB3  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
53 GJB5  
Two-hybrid Homo sapiens
54 MYF5  
Two-hybrid Homo sapiens
55 SPRYD7 57213
Two-hybrid Homo sapiens
56 KRTAP10-7  
Two-hybrid Homo sapiens
57 KRTAP9-8  
Two-hybrid Homo sapiens
58 MRM1  
Two-hybrid Homo sapiens
59 FNDC9  
Two-hybrid Homo sapiens
60 MIF4GD 57409
Two-hybrid Homo sapiens
61 KRTAP9-2  
Two-hybrid Homo sapiens
62 KRT33B 3884
Two-hybrid Homo sapiens
63 LRRC59 55379
Two-hybrid Homo sapiens
64 KCTD9  
Two-hybrid Homo sapiens
65 IKZF3  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
66 CCDC57 284001
Two-hybrid Homo sapiens
67 NBPF22P  
Two-hybrid Homo sapiens
68 KRTAP10-8  
Two-hybrid Homo sapiens
69 KRTAP1-5  
Two-hybrid Homo sapiens
70 WRB 7485
Two-hybrid Homo sapiens
71 GLI1  
Two-hybrid Homo sapiens
72 KRTAP10-3  
Two-hybrid Homo sapiens
73 RIMBP3 85376
Two-hybrid Homo sapiens
74 FAM209A 200232
Two-hybrid Homo sapiens
75 CLDN5 7122
Two-hybrid Homo sapiens
76 ESM1 11082
Two-hybrid Homo sapiens
77 NBPF6  
Two-hybrid Homo sapiens
78 CD79A  
Two-hybrid Homo sapiens
79 TMEM237 65062
Two-hybrid Homo sapiens
80 ZBTB39  
Two-hybrid Homo sapiens
81 PPARA  
Two-hybrid Homo sapiens
82 CPLX4  
Two-hybrid Homo sapiens
83 CCDC85B  
Two-hybrid Homo sapiens
84 TNS2 23371
Two-hybrid Homo sapiens
85 LIME1 54923
Two-hybrid Homo sapiens
86 KRTAP3-2  
Two-hybrid Homo sapiens
87 NUTM1  
Two-hybrid Homo sapiens
88 TNK2 10188
Two-hybrid Homo sapiens
89 BMF  
Two-hybrid Homo sapiens
90 TRAF2 7186
Two-hybrid Homo sapiens
91 SPRY2 10253
Two-hybrid Homo sapiens
92 TMEM80  
Two-hybrid Homo sapiens
93 PRDM14  
Two-hybrid Homo sapiens
94 BHLHB9 80823
Two-hybrid Homo sapiens
95 LDLRAD1  
Two-hybrid Homo sapiens
96 KLHL26  
Two-hybrid Homo sapiens
97 PGPEP1 54858
Two-hybrid Homo sapiens
98 BLZF1  
Two-hybrid Homo sapiens
99 NBPF19  
Two-hybrid Homo sapiens
100 MKRN3  
Two-hybrid Homo sapiens
101 KRTAP1-1  
Two-hybrid Homo sapiens
102 RBAK  
Two-hybrid Homo sapiens
103 KRTAP12-4  
Two-hybrid Homo sapiens
104 TSC1 7248
Two-hybrid Homo sapiens
105 ZNF792 126375
Two-hybrid Homo sapiens
106 LPXN 9404
Two-hybrid Homo sapiens
107 CEP44  
Two-hybrid Homo sapiens
108 SPRY3  
Two-hybrid Homo sapiens
109 TRIM37  
Two-hybrid Homo sapiens
110 ZIM2  
Two-hybrid Homo sapiens
111 TCF4  
Two-hybrid Homo sapiens
112 TRIM23 373
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
113 FAM161A  
Two-hybrid Homo sapiens
114 GPR37L1  
Two-hybrid Homo sapiens
115 CDR2  
Two-hybrid Homo sapiens
116 LDOC1  
Two-hybrid Homo sapiens
117 KCTD17 79734
Two-hybrid Homo sapiens
118 ATP6V0A2 23545
Affinity Capture-MS Homo sapiens
119 KCNK5  
Two-hybrid Homo sapiens
120 CCDC136  
Two-hybrid Homo sapiens
121 IGFBP6 3489
Two-hybrid Homo sapiens
122 SPRED1 161742
Two-hybrid Homo sapiens
123 PLSCR2  
Two-hybrid Homo sapiens
124 TRIP6 7205
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
125 MGST3 4259
Two-hybrid Homo sapiens
126 EFEMP2 30008
Two-hybrid Homo sapiens
127 TRAF1 7185
Two-hybrid Homo sapiens
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here