Experiment description of studies that identified IKZF2 in sEVs

1 Experiment ID 236 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH Enriched markers ✔ HSP90B1 Negative markers ✔ qNano Particle analysis Identified molecule mRNA Identification method RNA Sequencing PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N" Journal name Carcinogenesis Publication year 2015 Sample Hepatocellular carcinoma cells Sample name MHCC97L Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RT-PCR RNA Sequencing

2 Experiment ID 237 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH Enriched markers ✔ HSP90B1 Negative markers ✔ qNano Particle analysis Identified molecule mRNA Identification method RNA Sequencing PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N" Journal name Carcinogenesis Publication year 2015 Sample Hepatocytes Sample name MIHA Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RNA Sequencing

Protein-protein interactions for IKZF2

Protein Interactor ExoCarta ID Identification method PubMed Species 1 IKZF3   Affinity Capture-MS Homo sapiens Affinity Capture-Western Homo sapiens 2 LONRF1   Two-hybrid Homo sapiens 3 CBFB 865 Affinity Capture-MS Homo sapiens 4 Hoxa1   Two-hybrid Mus musculus PCA Mus musculus Affinity Capture-Western Mus musculus 5 NFATC1 4772 Affinity Capture-Western Homo sapiens Affinity Capture-MS Homo sapiens 6 APEX1 328 Affinity Capture-RNA Homo sapiens 7 AQP1 358 Two-hybrid Homo sapiens 8 IKZF5 64376 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 9 HDAC4   Reconstituted Complex Homo sapiens 10 CHD4 1108 Affinity Capture-Western Homo sapiens 11 HDAC2 3066 Affinity Capture-Western Homo sapiens 12 IKZF2 22807 Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens 13 NFATC2   Affinity Capture-Western Homo sapiens Affinity Capture-MS Homo sapiens 14 HDAC5 10014 Affinity Capture-Western Homo sapiens 15 NOTCH1 4851 Affinity Capture-MS Homo sapiens 16 SIN3A   Affinity Capture-Western Homo sapiens 17 CTBP1 1487 Two-hybrid Homo sapiens 18 SIN3B   Affinity Capture-Western Homo sapiens 19 IKZF1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-Western Homo sapiens 20 CTBP2 1488 Two-hybrid Homo sapiens View the network

Pathways in which IKZF2 is involved

No pathways found