Gene description for NFATC1
Gene name	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
Gene symbol	NFATC1
Other names/aliases	NF-ATC NFAT2 NFATc
Species	Homo sapiens
Database cross references - NFATC1
ExoCarta	ExoCarta_4772
Vesiclepedia	VP_4772
Entrez Gene	4772
HGNC	7775
MIM	600489
UniProt	O95644
NFATC1 identified in sEVs derived from the following tissue/cell type
Neuroblastoma cells	25944692

Gene ontology annotations for NFATC1

Molecular Function     RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000978 IBA     RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000978 ISS     DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981 IBA     DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981 ISA     DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981 ISS     transcription coactivator binding GO:0001223 IEA     DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228 ISS     nucleic acid binding GO:0003676 EXP     DNA-binding transcription factor activity GO:0003700 TAS     protein binding GO:0005515 IPI     FK506 binding GO:0005528 TAS     mitogen-activated protein kinase p38 binding GO:0048273 ISS     RNA polymerase II-specific DNA-binding transcription factor binding GO:0061629 ISS     sequence-specific double-stranded DNA binding GO:1990837 IDA Biological Process     aortic valve morphogenesis GO:0003180 ISS     pulmonary valve morphogenesis GO:0003184 ISS     response to muscle activity GO:0014850 IEA     calcineurin-NFAT signaling cascade GO:0033173 IBA     calcineurin-NFAT signaling cascade GO:0033173 IDA     intracellular signal transduction GO:0035556 IDA     wound healing GO:0042060 IEA     skeletal muscle adaptation GO:0043501 IEA     positive regulation of DNA-templated transcription GO:0045893 IDA     positive regulation of DNA-templated transcription GO:0045893 IDA     positive regulation of transcription by RNA polymerase II GO:0045944 IBA     positive regulation of transcription by RNA polymerase II GO:0045944 IDA     positive regulation of transcription by RNA polymerase II GO:0045944 IGI     positive regulation of transcription by RNA polymerase II GO:0045944 ISS     cellular response to tumor necrosis factor GO:0071356 IEA     cellular response to transforming growth factor beta stimulus GO:0071560 IEA     mononuclear cell differentiation GO:1903131 IEA     negative regulation of vascular associated smooth muscle cell differentiation GO:1905064 IDA     positive regulation of DNA biosynthetic process GO:2000573 IEA Subcellular Localization     chromatin GO:0000785 IDA     chromatin GO:0000785 ISA     nucleus GO:0005634 IBA     nucleus GO:0005634 IDA     nucleoplasm GO:0005654 IDA     nucleoplasm GO:0005654 TAS     transcription regulator complex GO:0005667 IBA     cytoplasm GO:0005737 ISS     cytosol GO:0005829 TAS     sarcoplasm GO:0016528 IEA     nuclear body GO:0016604 IDA     perinuclear region of cytoplasm GO:0048471 IEA