Experiment description of studies that identified AIM1 in sEVs

1 Experiment ID 1203 MISEV standards ✔ EM Biophysical techniques ✔ SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A Enriched markers ✘ Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 34887515     Organism Homo sapiens Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ." Journal name Nat Cell Biol Publication year 2021 Sample Colorectal cancer cells Sample name DiFi Isolation/purification methods Differential centrifugation Filtration Centrifugal ultrafiltration Ultracentrifugation OptiPrep density gradient centrifugation Flotation density - Molecules identified in the study Protein miRNA Methods used in the study Western blotting Mass spectrometry RNA sequencing

Protein-protein interactions for AIM1

Protein Interactor ExoCarta ID Identification method PubMed Species 1 SIX2   Affinity Capture-MS Homo sapiens 2 CXorf66   Affinity Capture-MS Homo sapiens 3 FBXL4 26235 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 4 LAIR2   Affinity Capture-MS Homo sapiens 5 ERBB2 2064 Affinity Capture-MS Homo sapiens 6 C18orf21   Affinity Capture-MS Homo sapiens 7 RPL10 6134 Affinity Capture-MS Homo sapiens 8 AGPAT1 10554 Affinity Capture-MS Homo sapiens 9 KRT18 3875 Proximity Label-MS Homo sapiens 10 DEFB114   Affinity Capture-MS Homo sapiens 11 TBC1D22B   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 12 KRT8 3856 Proximity Label-MS Homo sapiens 13 SPARCL1   Affinity Capture-MS Homo sapiens 14 PPP2R5B 5526 Affinity Capture-MS Homo sapiens 15 CCR1   Affinity Capture-MS Homo sapiens 16 CUL3 8452 Affinity Capture-MS Homo sapiens 17 CAPZA2 830 Affinity Capture-MS Homo sapiens 18 CDK15   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 19 ZNF829   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 20 PTDSS1 9791 Affinity Capture-MS Homo sapiens 21 KIFAP3 22920 Affinity Capture-MS Homo sapiens 22 SOCS7   Affinity Capture-MS Homo sapiens 23 NPSR1   Affinity Capture-MS Homo sapiens 24 PEMT   Affinity Capture-MS Homo sapiens 25 RNF115   Affinity Capture-MS Homo sapiens 26 GSK3A 2931 Affinity Capture-MS Homo sapiens 27 PLD5   Affinity Capture-MS Homo sapiens 28 XPO1 7514 Affinity Capture-MS Homo sapiens 29 NEFL 4747 Affinity Capture-MS Homo sapiens 30 MBNL1 4154 Affinity Capture-MS Homo sapiens 31 ANXA9   Affinity Capture-MS Homo sapiens 32 INA 9118 Affinity Capture-MS Homo sapiens 33 ISCA2 122961 Affinity Capture-MS Homo sapiens 34 CDH1 999 Proximity Label-MS Homo sapiens 35 CSGALNACT1 55790 Affinity Capture-MS Homo sapiens 36 NEFM 4741 Proximity Label-MS Homo sapiens Affinity Capture-MS Homo sapiens 37 FBXO3   Affinity Capture-MS Homo sapiens 38 KDELR2 11014 Affinity Capture-MS Homo sapiens 39 PPP2R5E 5529 Affinity Capture-MS Homo sapiens 40 SARAF   Affinity Capture-MS Homo sapiens 41 IL31RA   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 42 PIGT 51604 Affinity Capture-MS Homo sapiens 43 PGK1 5230 Cross-Linking-MS (XL-MS) Homo sapiens 44 GOT1 2805 Affinity Capture-MS Homo sapiens 45 IQUB   Affinity Capture-MS Homo sapiens 46 PPP2CA 5515 Affinity Capture-MS Homo sapiens 47 FOS 2353 Affinity Capture-MS Homo sapiens 48 SSUH2   Affinity Capture-MS Homo sapiens 49 SGIP1   Affinity Capture-MS Homo sapiens 50 CD44 960 Affinity Capture-MS Homo sapiens 51 PPP2R5A 5525 Affinity Capture-MS Homo sapiens 52 MRPL38   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 53 SOST   Affinity Capture-MS Homo sapiens 54 ZMAT4   Affinity Capture-MS Homo sapiens 55 STX17 55014 Affinity Capture-MS Homo sapiens 56 FOXD4L6   Affinity Capture-MS Homo sapiens 57 PYHIN1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 58 PHF11 51131 Affinity Capture-MS Homo sapiens 59 ZMYM6NB   Affinity Capture-MS Homo sapiens View the network

Pathways in which AIM1 is involved

No pathways found