Gene description for PRR4
Gene name proline rich 4 (lacrimal)
Gene symbol PRR4
Other names/aliases LPRP
PROL4
Species Homo sapiens
 Database cross references - PRR4
ExoCarta ExoCarta_11272
Vesiclepedia VP_11272
Entrez Gene 11272
HGNC 18020
MIM 605359
UniProt Q16378  
 PRR4 identified in sEVs derived from the following tissue/cell type
Mesenchymal stem cells Unpublished / Not applicable
 Gene ontology annotations for PRR4
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    visual perception GO:0007601 TAS
Subcellular Localization
    extracellular space GO:0005615 HDA
 Experiment description of studies that identified PRR4 in sEVs
1
Experiment ID 126
MISEV standards
Biophysical techniques
GAPDH
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors "Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim"
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
 Protein-protein interactions for PRR4
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 LAT 27040
Two-hybrid Homo sapiens
2 LRRC15 131578
Affinity Capture-MS Homo sapiens
3 SERPINA1 5265
Affinity Capture-MS Homo sapiens
4 HBB 3043
Affinity Capture-MS Homo sapiens
5 SNX27 81609
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
6 FKBP14  
Affinity Capture-MS Homo sapiens
7 OR13C3  
Affinity Capture-MS Homo sapiens
8 STATH  
Affinity Capture-MS Homo sapiens
9 DHRS12  
Affinity Capture-MS Homo sapiens
10 DDX3X 1654
Affinity Capture-MS Homo sapiens
11 TMEM176B 28959
Affinity Capture-MS Homo sapiens
12 UBQLN2 29978
Two-hybrid Homo sapiens
13 GC 2638
Affinity Capture-MS Homo sapiens
14 DDX31  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
15 GNG8  
Affinity Capture-MS Homo sapiens
16 SLC25A10 1468
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
17 UBQLN1 29979
Two-hybrid Homo sapiens
18 FGB 2244
Affinity Capture-MS Homo sapiens
19 ASNA1 439
Two-hybrid Homo sapiens
20 CP 1356
Affinity Capture-MS Homo sapiens
21 EBF2  
Affinity Capture-MS Homo sapiens
22 WHSC1 7468
Affinity Capture-MS Homo sapiens
23 CLU 1191
Affinity Capture-MS Homo sapiens
24 S100A9 6280
Affinity Capture-MS Homo sapiens
25 AZGP1 563
Affinity Capture-MS Homo sapiens
26 TF 7018
Affinity Capture-MS Homo sapiens
27 GOLGA8A 23015
Affinity Capture-MS Homo sapiens
28 HPX 3263
Affinity Capture-MS Homo sapiens
29 USB1  
Affinity Capture-MS Homo sapiens
30 SGTB  
Two-hybrid Homo sapiens
31 HP 3240
Affinity Capture-MS Homo sapiens
32 B3GNT2 10678
Affinity Capture-MS Homo sapiens
33 PMEPA1 56937
Affinity Capture-MS Homo sapiens
34 ITLN2  
Affinity Capture-MS Homo sapiens
35 ORM1 5004
Affinity Capture-MS Homo sapiens
36 EFNA4  
Affinity Capture-MS Homo sapiens
37 HBM  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
38 LRRC8E 80131
Affinity Capture-MS Homo sapiens
39 MRPS5 64969
Affinity Capture-MS Homo sapiens
40 KCNIP4 80333
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
41 P3H3 10536
Affinity Capture-MS Homo sapiens
42 LCN1 3933
Affinity Capture-MS Homo sapiens
43 ATP11C 286410
Affinity Capture-MS Homo sapiens
44 DDX39B 7919
Affinity Capture-MS Homo sapiens
45 IGLC1 3537
Affinity Capture-MS Homo sapiens
46 SERPINA3 12
Affinity Capture-MS Homo sapiens
47 GJB5  
Affinity Capture-MS Homo sapiens
48 GIP  
Affinity Capture-MS Homo sapiens
49 APOA1 335
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which PRR4 is involved
No pathways found





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