Gene description for Hspe1
Gene name
heat shock protein 1 (chaperonin 10)
Gene symbol
Hspe1
Other names/aliases
10kDa Hsp10 mt-cpn10
Species
Mus musculus
Database cross references - Hspe1
ExoCarta
ExoCarta_15528
Vesiclepedia
VP_15528
Entrez Gene
15528
UniProt
Q64433
Hspe1 identified in sEVs derived from the following tissue/cell type
Melanoma cells
34957415
Melanoma cells
34957415
Gene ontology annotations for Hspe1
Experiment description of studies that identified Hspe1 in sEVs
1
Experiment ID
1117
MISEV standards
✘
Biophysical techniques
✔
Cd81|Icam1
Enriched markers
✘
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
34957415
Organism
Mus musculus
Experiment description
Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism
Authors
"GarcÃa-Silva S, Benito-MartÃn A, Nogués L, Hernández-Barranco A, Mazariegos MS, Santos V, Hergueta-Redondo M, Ximénez-Embún P, Kataru RP, Lopez AA, Merino C, Sánchez-Redondo S, Graña-Castro O, Matei I, Nicolás-Avila JÃ, Torres-Ruiz R, RodrÃguez-Perales S, MartÃnez L, Pérez-MartÃnez M, Mata G, Szumera-Ciećkiewicz A, Kalinowska I, Saltari A, MartÃnez-Gómez JM, Hogan SA, Saragovi HU, Ortega S, Garcia-Martin C, Boskovic J, Levesque MP, Rutkowski P, Hidalgo A, Muñoz J, MegÃas D, Mehrara BJ, Lyden D, Peinado H."
Journal name
Nat Cancer
Publication year
2021
Sample
Melanoma cells
Sample name
B16-F1R2
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
2
Experiment ID
1118
MISEV standards
✘
Biophysical techniques
✔
Cd81|Icam1
Enriched markers
✘
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
34957415
Organism
Mus musculus
Experiment description
Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism
Authors
"GarcÃa-Silva S, Benito-MartÃn A, Nogués L, Hernández-Barranco A, Mazariegos MS, Santos V, Hergueta-Redondo M, Ximénez-Embún P, Kataru RP, Lopez AA, Merino C, Sánchez-Redondo S, Graña-Castro O, Matei I, Nicolás-Avila JÃ, Torres-Ruiz R, RodrÃguez-Perales S, MartÃnez L, Pérez-MartÃnez M, Mata G, Szumera-Ciećkiewicz A, Kalinowska I, Saltari A, MartÃnez-Gómez JM, Hogan SA, Saragovi HU, Ortega S, Garcia-Martin C, Boskovic J, Levesque MP, Rutkowski P, Hidalgo A, Muñoz J, MegÃas D, Mehrara BJ, Lyden D, Peinado H."
Journal name
Nat Cancer
Publication year
2021
Sample
Melanoma cells
Sample name
B16-F1R2
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
Protein-protein interactions for Hspe1
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
Ppif
Cross-Linking-MS (XL-MS)
Mus musculus
2
Ubc
Reconstituted Complex
Mus musculus
3
Tmem173
Proximity Label-MS
Mus musculus
4
D10Jhu81e
Cross-Linking-MS (XL-MS)
Mus musculus
5
Hspd1
15510
Cross-Linking-MS (XL-MS)
Mus musculus
Cross-Linking-MS (XL-MS)
Mus musculus
6
Taldo1
21351
Co-fractionation
Mus musculus
7
Tfe3
Affinity Capture-MS
Mus musculus
8
Hspe1
15528
Cross-Linking-MS (XL-MS)
Mus musculus
Cross-Linking-MS (XL-MS)
Mus musculus
Cross-Linking-MS (XL-MS)
Mus musculus
Cross-Linking-MS (XL-MS)
Mus musculus
9
Atg16l1
Affinity Capture-MS
Mus musculus
10
Unk
Affinity Capture-RNA
Mus musculus
11
Fdxr
Co-fractionation
Mus musculus
12
Thop1
Co-fractionation
Mus musculus
View the network
image/svg+xml
Pathways in which Hspe1 is involved