Gene description for E2F2
Gene name	E2F transcription factor 2
Gene symbol	E2F2
Other names/aliases	E2F-2
Species	Homo sapiens
Database cross references - E2F2
ExoCarta	ExoCarta_1870
Vesiclepedia	VP_1870
Entrez Gene	1870
HGNC	3114
MIM	600426
UniProt	Q14209
E2F2 identified in sEVs derived from the following tissue/cell type
Hepatocellular carcinoma cells	26054723

Gene ontology annotations for E2F2

Molecular Function     RNA polymerase II transcription regulatory region sequence-specific DNA binding GO:0000977 IDA     RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000978 IBA     DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981 IBA     DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981 ISA     cis-regulatory region sequence-specific DNA binding GO:0000987 IDA     DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228 IDA     DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228 IDA     DNA binding GO:0003677 TAS     DNA-binding transcription factor activity GO:0003700 NAS     protein binding GO:0005515 IPI     sequence-specific DNA binding GO:0043565 IDA     protein dimerization activity GO:0046983 IEA     sequence-specific double-stranded DNA binding GO:1990837 IDA Biological Process     regulation of DNA-templated transcription GO:0006355 ISS     regulation of transcription by RNA polymerase II GO:0006357 IBA     transcription initiation at RNA polymerase II promoter GO:0006367 TAS     positive regulation of transcription by RNA polymerase II GO:0045944 IDA     regulation of cell cycle GO:0051726 IEA     intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 IEA     negative regulation of sprouting angiogenesis GO:1903671 IGI     lens fiber cell apoptotic process GO:1990086 IEA Subcellular Localization     chromatin GO:0000785 ISA     nucleoplasm GO:0005654 TAS     Rb-E2F complex GO:0035189 ISS     RNA polymerase II transcription regulator complex GO:0090575 IBA     RNA polymerase II transcription regulator complex GO:0090575 IDA     RNA polymerase II transcription regulator complex GO:0090575 ISS