Gene description for Ptprs
Gene name
protein tyrosine phosphatase, receptor type, S
Gene symbol
Ptprs
Other names/aliases
AL022616 PTP PTP-NU3 PTPNU-3 PTPsigma Ptpt9 R-PTP-S RPTPsigma
Species
Mus musculus
Database cross references - Ptprs
ExoCarta
ExoCarta_19280
Vesiclepedia
VP_19280
Entrez Gene
19280
UniProt
B0V2N1
Ptprs identified in sEVs derived from the following tissue/cell type
Melanoma cells
34957415
Melanoma cells
34957415
Melanoma cells
34957415
Gene ontology annotations for Ptprs
Experiment description of studies that identified Ptprs in sEVs
1
Experiment ID
1101
MISEV standards
✔
EM
Biophysical techniques
✔
Cd81|Cd9|Tfrc|Gapdh|Lamp1
Enriched markers
✔
GOLGA2|CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
34957415
Organism
Mus musculus
Experiment description
Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism
Authors
"GarcÃa-Silva S, Benito-MartÃn A, Nogués L, Hernández-Barranco A, Mazariegos MS, Santos V, Hergueta-Redondo M, Ximénez-Embún P, Kataru RP, Lopez AA, Merino C, Sánchez-Redondo S, Graña-Castro O, Matei I, Nicolás-Avila JÃ, Torres-Ruiz R, RodrÃguez-Perales S, MartÃnez L, Pérez-MartÃnez M, Mata G, Szumera-Ciećkiewicz A, Kalinowska I, Saltari A, MartÃnez-Gómez JM, Hogan SA, Saragovi HU, Ortega S, Garcia-Martin C, Boskovic J, Levesque MP, Rutkowski P, Hidalgo A, Muñoz J, MegÃas D, Mehrara BJ, Lyden D, Peinado H."
Journal name
Nat Cancer
Publication year
2021
Sample
Melanoma cells
Sample name
B16-F1
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
2
Experiment ID
1102
MISEV standards
✔
EM
Biophysical techniques
✔
Cd81|Cd9|Tfrc|Gapdh|Lamp1
Enriched markers
✔
GOLGA2|CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
34957415
Organism
Mus musculus
Experiment description
Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism
Authors
"GarcÃa-Silva S, Benito-MartÃn A, Nogués L, Hernández-Barranco A, Mazariegos MS, Santos V, Hergueta-Redondo M, Ximénez-Embún P, Kataru RP, Lopez AA, Merino C, Sánchez-Redondo S, Graña-Castro O, Matei I, Nicolás-Avila JÃ, Torres-Ruiz R, RodrÃguez-Perales S, MartÃnez L, Pérez-MartÃnez M, Mata G, Szumera-Ciećkiewicz A, Kalinowska I, Saltari A, MartÃnez-Gómez JM, Hogan SA, Saragovi HU, Ortega S, Garcia-Martin C, Boskovic J, Levesque MP, Rutkowski P, Hidalgo A, Muñoz J, MegÃas D, Mehrara BJ, Lyden D, Peinado H."
Journal name
Nat Cancer
Publication year
2021
Sample
Melanoma cells
Sample name
B16-F10
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry Flow cytometry
3
Experiment ID
1103
MISEV standards
✔
EM
Biophysical techniques
✔
Cd81|Cd9|Tfrc|Gapdh|Lamp1
Enriched markers
✔
GOLGA2|CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
34957415
Organism
Mus musculus
Experiment description
Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism
Authors
"GarcÃa-Silva S, Benito-MartÃn A, Nogués L, Hernández-Barranco A, Mazariegos MS, Santos V, Hergueta-Redondo M, Ximénez-Embún P, Kataru RP, Lopez AA, Merino C, Sánchez-Redondo S, Graña-Castro O, Matei I, Nicolás-Avila JÃ, Torres-Ruiz R, RodrÃguez-Perales S, MartÃnez L, Pérez-MartÃnez M, Mata G, Szumera-Ciećkiewicz A, Kalinowska I, Saltari A, MartÃnez-Gómez JM, Hogan SA, Saragovi HU, Ortega S, Garcia-Martin C, Boskovic J, Levesque MP, Rutkowski P, Hidalgo A, Muñoz J, MegÃas D, Mehrara BJ, Lyden D, Peinado H."
Journal name
Nat Cancer
Publication year
2021
Sample
Melanoma cells
Sample name
B16-F1R2
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry Flow cytometry
Protein-protein interactions for Ptprs
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
PTPRF
5792
Affinity Capture-Western
Homo sapiens
2
Tnik
Affinity Capture-MS
Mus musculus
3
Ptprb
Co-fractionation
Mus musculus
4
Ptpn2
Co-fractionation
Mus musculus
5
PTPRM
5797
Affinity Capture-Western
Homo sapiens
6
Ptprf
Co-fractionation
Mus musculus
7
Ptpn6
15170
Co-fractionation
Mus musculus
8
Ptpn3
Co-fractionation
Mus musculus
9
Ptprg
Co-fractionation
Mus musculus
10
Ptpra
19262
Affinity Capture-Western
Mus musculus
Co-fractionation
Mus musculus
11
Tsc1
Affinity Capture-MS
Mus musculus
12
Kctd13
Affinity Capture-MS
Mus musculus
13
Ptpre
Affinity Capture-Western
Mus musculus
Co-fractionation
Mus musculus
14
Ptprc
19264
Affinity Capture-Western
Mus musculus
15
Ptprm
Co-fractionation
Mus musculus
16
Tmem173
Proximity Label-MS
Mus musculus
17
Ptprq
Co-fractionation
Mus musculus
18
Ptprj
19271
Co-fractionation
Mus musculus
19
Ptpru
Co-fractionation
Mus musculus
20
Ptpn14
Co-fractionation
Mus musculus
21
Ptpn13
Co-fractionation
Mus musculus
22
Fancd2
Affinity Capture-MS
Mus musculus
View the network
image/svg+xml
Pathways in which Ptprs is involved