Gene description for PTPRF
Gene name protein tyrosine phosphatase, receptor type, F
Gene symbol PTPRF
Other names/aliases BNAH2
LAR
Species Homo sapiens
 Database cross references - PTPRF
ExoCarta ExoCarta_5792
Vesiclepedia VP_5792
Entrez Gene 5792
HGNC 9670
MIM 179590
UniProt P10586  
 PTPRF identified in sEVs derived from the following tissue/cell type
Bladder cancer cells 20224111    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 19837982    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 34887515    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Mesenchymal stem cells 36408942    
Neuroblastoma cells 25944692    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Saliva 19199708    
 Gene ontology annotations for PTPRF
Molecular Function
    phosphoprotein phosphatase activity GO:0004721 IDA
    protein tyrosine phosphatase activity GO:0004725 IBA
    protein tyrosine phosphatase activity GO:0004725 IDA
    protein tyrosine phosphatase activity GO:0004725 IMP
    non-membrane spanning protein tyrosine phosphatase activity GO:0004726 IEA
    transmembrane receptor protein tyrosine phosphatase activity GO:0005001 TAS
    heparin binding GO:0008201 IEA
    protein tyrosine phosphatase activity, metal-dependent GO:0030946 IEA
    chondroitin sulfate proteoglycan binding GO:0035373 IEA
    protein-containing complex binding GO:0044877 IEA
    cell adhesion molecule binding GO:0050839 IPI
    histone H2AXY142 phosphatase activity GO:0140793 IEA
Biological Process
    chromatin remodeling GO:0006338 IEA
    cell adhesion GO:0007155 TAS
    signal transduction GO:0007165 IBA
    cell surface receptor protein tyrosine phosphatase signaling pathway GO:0007185 TAS
    nervous system development GO:0007399 IBA
    cell migration GO:0016477 IMP
    neuron projection regeneration GO:0031102 IEA
    peptidyl-tyrosine dephosphorylation GO:0035335 IMP
    regulation of axon regeneration GO:0048679 IEA
    synaptic membrane adhesion GO:0099560 IBA
    synaptic membrane adhesion GO:0099560 IDA
    synaptic membrane adhesion GO:0099560 IMP
    negative regulation of receptor binding GO:1900121 IMP
Subcellular Localization
    plasma membrane GO:0005886 TAS
    neuron projection GO:0043005 IEA
    neuronal cell body GO:0043025 IEA
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified PTPRF in sEVs
1
Experiment ID 76
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|GAPDH|HSP90|CD81|CD9|CD63|LAMP1|MHCI
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20224111    
Organism Homo sapiens
Experiment description Proteomics analysis of bladder cancer exosomes.
Authors "Welton JL, Khanna S, Giles PJ, Brennan P, Brewis IA, Staffurth J, Mason MD, Clayton A."
Journal name MCP
Publication year 2010
Sample Bladder cancer cells
Sample name HT1376
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.10-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [MALDI TOF/TOF]
Western blotting
FACS
2
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
6
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
7
Experiment ID 498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
8
Experiment ID 21
MISEV standards
✔
EM|IEM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD63
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry   
PubMed ID 19837982    
Organism Homo sapiens
Experiment description Proteomic and bioinformatic analysis of immunoaffinity-purified exosomes derived from the human colon tumor cell line LIM1215.
Authors "Suresh Mathivanan, Justin W.E. Lim, Bow J. Tauro, Hong Ji, Robert L. Moritz and Richard J. Simpson"
Journal name MCP
Publication year 2009
Sample Colorectal cancer cells
Sample name LIM1215
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.10-1.12 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [Orbitrap]
Western blotting
9
Experiment ID 207
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DKO-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
10
Experiment ID 208
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name Dks-8
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
11
Experiment ID 209
MISEV standards
✘ Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DLD-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
12
Experiment ID 1203
MISEV standards
✔
EM
Biophysical techniques
✔
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
13
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
14
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
15
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
16
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
17
Experiment ID 224
MISEV standards
✔
EM|AFM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81
Enriched markers
✔
GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
18
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
19
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
20
Experiment ID 66
MISEV standards
✔
IEM
Biophysical techniques
✔
TSG101|Alix|CD63|CD81
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19199708    
Organism Homo sapiens
Experiment description Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Authors "Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR"
Journal name JPR
Publication year 2009
Sample Saliva
Sample name Saliva
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for PTPRF
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 RNF149 284996
Affinity Capture-MS Homo sapiens
2 ADRBK1 156
Co-fractionation Homo sapiens
3 RYK 6259
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
4 SGCA  
Affinity Capture-MS Homo sapiens
5 LRRIQ1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
6 ARHGEF2 9181
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
7 IZUMO1  
Affinity Capture-MS Homo sapiens
8 DNAAF5 54919
Co-fractionation Homo sapiens
9 CYYR1  
Affinity Capture-MS Homo sapiens
10 LDHB 3945
Two-hybrid Homo sapiens
11 LDHA 3939
Two-hybrid Homo sapiens
12 IL20RB  
Affinity Capture-MS Homo sapiens
13 CSNK1G2 1455
Affinity Capture-MS Homo sapiens
14 MARCH2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
15 PCDH12 51294
Affinity Capture-MS Homo sapiens
16 HSPA1L 3305
Two-hybrid Homo sapiens
17 ROCK2 9475
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
18 DIAPH1 1729
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
19 IL22RA2  
Affinity Capture-MS Homo sapiens
20 RET 5979
Reconstituted Complex Homo sapiens
21 PRPF40A 55660
Two-hybrid Homo sapiens
22 FFAR1  
Affinity Capture-MS Homo sapiens
23 HEPACAM2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
24 OMG  
Reconstituted Complex Homo sapiens
25 ACAT1 38
Two-hybrid Homo sapiens
26 TSTA3 7264
Co-fractionation Homo sapiens
27 BTN2A1 11120
Affinity Capture-MS Homo sapiens
28 PPFIA3 8541
Two-hybrid Homo sapiens
29 FAM171A2 284069
Proximity Label-MS Homo sapiens
30 PPP2R5D 5528
Co-fractionation Homo sapiens
31 BCAT2 587
Cross-Linking-MS (XL-MS) Homo sapiens
32 NPLOC4 55666
Co-fractionation Homo sapiens
33 TMEM231 79583
Affinity Capture-MS Homo sapiens
34 NID1 4811
Reconstituted Complex Homo sapiens
35 ZNF512B  
Two-hybrid Homo sapiens
36 CDH16  
Affinity Capture-MS Homo sapiens
37 GPRC5B 51704
Affinity Capture-MS Homo sapiens
38 RHOA 387
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
39 ACVR2B  
Affinity Capture-MS Homo sapiens
40 RNF133  
Affinity Capture-MS Homo sapiens
41 LACTB 114294
Two-hybrid Homo sapiens
42 SOWAHC  
Two-hybrid Homo sapiens
43 EDAR  
Affinity Capture-MS Homo sapiens
44 EEF1G 1937
Two-hybrid Homo sapiens
45 HACL1 26061
Co-fractionation Homo sapiens
46 IL13RA2 3598
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
47 GAPDH 2597
Two-hybrid Homo sapiens
48 EEF1A1 1915
Two-hybrid Homo sapiens
49 CLDND1 56650
Affinity Capture-MS Homo sapiens
50 RNF11 26994
Affinity Capture-MS Homo sapiens
51 ARHGEF11 9826
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
52 PROKR1  
Affinity Capture-MS Homo sapiens
53 CBR1 873
Two-hybrid Homo sapiens
54 LTBR 4055
Affinity Capture-MS Homo sapiens
55 METTL13 51603
Co-fractionation Homo sapiens
56 UNK  
Affinity Capture-RNA Homo sapiens
57 PPFIA2 8499
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
58 PFKM 5213
Co-fractionation Homo sapiens
59 CDKN2AIP  
Affinity Capture-MS Homo sapiens
60 MANSC1 54682
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
61 ATP5A1 498
Two-hybrid Homo sapiens
62 FOXA1  
Affinity Capture-MS Homo sapiens
63 PTPRN2  
Affinity Capture-MS Homo sapiens
64 CD83  
Affinity Capture-MS Homo sapiens
65 NAA50 80218
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
66 ABCE1 6059
Affinity Capture-MS Homo sapiens
67 CEACAM21  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
68 CLU 1191
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
69 TMEM150A  
Affinity Capture-MS Homo sapiens
70 MCAM 4162
Proximity Label-MS Homo sapiens
71 SUGT1 10910
Proximity Label-MS Homo sapiens
72 TIGIT  
Affinity Capture-MS Homo sapiens
73 FAM207A  
Cross-Linking-MS (XL-MS) Homo sapiens
74 GIT1 28964
Affinity Capture-Western Homo sapiens
75 DRAP1 10589
Cross-Linking-MS (XL-MS) Homo sapiens
76 NTRK1 4914
Affinity Capture-MS Homo sapiens
77 NPDC1  
Affinity Capture-MS Homo sapiens
78 RAB2A 5862
Proximity Label-MS Homo sapiens
79 ARRDC3 57561
Affinity Capture-MS Homo sapiens
80 ACTB 60
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
81 TUBA1B 10376
Two-hybrid Homo sapiens
82 PML 5371
Affinity Capture-MS Homo sapiens
83 ARHGEF12 23365
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
84 MRAP2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
85 PICALM 8301
Co-fractionation Homo sapiens
86 TMEM171  
Affinity Capture-MS Homo sapiens
87 SEC61B 10952
Proximity Label-MS Homo sapiens
88 NUDCD3 23386
Affinity Capture-MS Homo sapiens
89 SYT11 23208
Affinity Capture-MS Homo sapiens
90 TTI1 9675
Proximity Label-MS Homo sapiens
91 MARCH3 115123
Affinity Capture-MS Homo sapiens
92 UFD1L 7353
Co-fractionation Homo sapiens
93 PCDHGB1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
94 RAP1GDS1 5910
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
95 TOMM34 10953
Co-fractionation Homo sapiens
96 GPC4 2239
Reconstituted Complex Homo sapiens
97 Ptpra 19262
Affinity Capture-Western Mus musculus
98 MARCH1  
Affinity Capture-MS Homo sapiens
99 ARRDC4  
Affinity Capture-MS Homo sapiens
100 KCNC3 3748
Affinity Capture-MS Homo sapiens
101 DEPDC1B 55789
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
102 PCDHAC1  
Affinity Capture-MS Homo sapiens
103 RNF128  
Affinity Capture-MS Homo sapiens
104 CTNNB1 1499
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
105 MARCH8  
Affinity Capture-MS Homo sapiens
106 TRIO 7204
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
107 TUBB4B 10383
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
108 CLEC4A  
Affinity Capture-MS Homo sapiens
109 EGFR 1956
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
110 SEPT9 10801
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
111 WFDC2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
112 ARF6 382
Proximity Label-MS Homo sapiens
113 SEMG2 6407
Two-hybrid Homo sapiens
114 RAB35 11021
Proximity Label-MS Homo sapiens
115 SEMG1 6406
Two-hybrid Homo sapiens
116 KCNE3  
Affinity Capture-MS Homo sapiens
117 LRTM1  
Affinity Capture-MS Homo sapiens
118 OPTC  
Affinity Capture-MS Homo sapiens
119 CNR2  
Affinity Capture-MS Homo sapiens
120 PPWD1 23398
Co-fractionation Homo sapiens
121 RELT  
Affinity Capture-MS Homo sapiens
122 ATP6V0E1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
123 HSPA1A 3303
Two-hybrid Homo sapiens
124 DLL1  
Affinity Capture-MS Homo sapiens
125 SCN2B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
126 HSPA9 3313
Two-hybrid Homo sapiens
127 DDX1 1653
Co-fractionation Homo sapiens
128 PPFIA1 8500
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
129 PHGDH 26227
Cross-Linking-MS (XL-MS) Homo sapiens
130 ARPC3 10094
Co-fractionation Homo sapiens
131 GLS 2744
Co-fractionation Homo sapiens
132 LAMTOR1 55004
Affinity Capture-MS Homo sapiens
133 SKIL  
Two-hybrid Homo sapiens
134 TGFBR2 7048
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
135 JUP 3728
Reconstituted Complex Homo sapiens
136 TP53 7157
Affinity Capture-MS Homo sapiens
137 OPALIN  
Affinity Capture-MS Homo sapiens
138 HSPA8 3312
Two-hybrid Homo sapiens
139 FCGRT 2217
Affinity Capture-MS Homo sapiens
140 TPTE  
Affinity Capture-MS Homo sapiens
141 TMEM30B 161291
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
142 Ptpre  
Affinity Capture-Western Mus musculus
Affinity Capture-Western Mus musculus
143 TSPAN17 26262
Affinity Capture-MS Homo sapiens
144 EFNB1 1947
Affinity Capture-MS Homo sapiens
145 HIST1H2BD 3017
Cross-Linking-MS (XL-MS) Homo sapiens
146 DLK1  
Affinity Capture-MS Homo sapiens
147 HSP90AA1 3320
Two-hybrid Homo sapiens
148 C11orf52 91894
Proximity Label-MS Homo sapiens
149 PTGER3  
Affinity Capture-MS Homo sapiens
150 HNRNPK 3190
Cross-Linking-MS (XL-MS) Homo sapiens
151 MAPK1 5594
Co-fractionation Homo sapiens
152 Ptprs 19280
Affinity Capture-Western Mus musculus
153 BSND  
Affinity Capture-MS Homo sapiens
154 PTPRS 5802
Proximity Label-MS Homo sapiens
155 PMVK 10654
Co-fractionation Homo sapiens
156 KCNE4  
Affinity Capture-MS Homo sapiens
157 PCDHB16  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
158 CUL7 9820
Affinity Capture-MS Homo sapiens
159 KRAS 3845
Proximity Label-MS Homo sapiens
160 RAB5C 5878
Proximity Label-MS Homo sapiens
161 LCN2 3934
Affinity Capture-MS Homo sapiens
162 Ptprd  
Affinity Capture-Western Mus musculus
163 PIANP  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
164 HSPA5 3309
Two-hybrid Homo sapiens
165 CAV1 857
Proximity Label-MS Homo sapiens
Affinity Capture-Western Homo sapiens
166 ESYT1 23344
Cross-Linking-MS (XL-MS) Homo sapiens
167 SEPHS1 22929
Co-fractionation Homo sapiens
168 KIAA1644  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here