Gene description for DDX1
Gene name DEAD (Asp-Glu-Ala-Asp) box helicase 1
Gene symbol DDX1
Other names/aliases DBP-RB
UKVH5d
Species Homo sapiens
 Database cross references - DDX1
ExoCarta ExoCarta_1653
Vesiclepedia VP_1653
Entrez Gene 1653
HGNC 2734
MIM 601257
UniProt Q92499  
 DDX1 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 34887515    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Neuroblastoma cells 25944692    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
T lymphocytes 34108659    
Thymus 23844026    
 Gene ontology annotations for DDX1
Molecular Function
    DNA binding GO:0003677 IEA
    chromatin binding GO:0003682 IDA
    DNA clamp loader activity GO:0003689 IEA
    transcription coregulator activity GO:0003712 IDA
    RNA binding GO:0003723 HDA
    RNA helicase activity GO:0003724 IDA
    double-stranded RNA binding GO:0003725 IEA
    nuclease activity GO:0004518 IDA
    exonuclease activity GO:0004527 IEA
    protein binding GO:0005515 IPI
    ATP binding GO:0005524 IEA
    poly(A) binding GO:0008143 IDA
    ATP hydrolysis activity GO:0016887 IEA
    DNA/RNA helicase activity GO:0033677 IDA
    cohesin loader activity GO:0061775 IEA
    chromatin extrusion motor activity GO:0140584 IEA
    ATP-dependent H3-H4 histone complex chaperone activity GO:0140665 IEA
    ATP-dependent H2AZ histone chaperone activity GO:0140849 IEA
Biological Process
    spliceosomal complex assembly GO:0000245 NAS
    positive regulation of myeloid dendritic cell cytokine production GO:0002735 IEA
    double-strand break repair GO:0006302 IDA
    chromatin remodeling GO:0006338 IEA
    tRNA splicing, via endonucleolytic cleavage and ligation GO:0006388 IMP
    tRNA splicing, via endonucleolytic cleavage and ligation GO:0006388 NAS
    regulation of translational initiation GO:0006446 NAS
    DNA duplex unwinding GO:0032508 IDA
    positive regulation of canonical NF-kappaB signal transduction GO:0043123 ISS
    response to exogenous dsRNA GO:0043330 IEA
    innate immune response GO:0045087 IEA
    defense response to virus GO:0051607 IEA
    nucleic acid metabolic process GO:0090304 IDA
    chromatin looping GO:0140588 IEA
    protein localization to cytoplasmic stress granule GO:1903608 IMP
Subcellular Localization
    nucleus GO:0005634 IDA
    nucleus GO:0005634 NAS
    nucleoplasm GO:0005654 IDA
    nucleoplasm GO:0005654 TAS
    cytoplasm GO:0005737 IDA
    cytoplasm GO:0005737 NAS
    mitochondrion GO:0005739 ISS
    cytosol GO:0005829 IDA
    cytoplasmic stress granule GO:0010494 IDA
    membrane GO:0016020 HDA
    cleavage body GO:0071920 IDA
    tRNA-splicing ligase complex GO:0072669 IDA
    tRNA-splicing ligase complex GO:0072669 NAS
    ribonucleoprotein complex GO:1990904 IDA
 Experiment description of studies that identified DDX1 in sEVs
1
Experiment ID 489
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
10
Experiment ID 498
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
11
Experiment ID 1203
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
12
Experiment ID 407
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
13
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
14
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
15
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
16
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
17
Experiment ID 405
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
18
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
19
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
20
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
21
Experiment ID 417
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
22
Experiment ID 411
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
23
Experiment ID 488
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
24
Experiment ID 418
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
25
Experiment ID 418
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
26
Experiment ID 224
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
27
Experiment ID 413
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
28
Experiment ID 211
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
29
Experiment ID 212
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
30
Experiment ID 406
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
31
Experiment ID 415
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
32
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
33
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
34
Experiment ID 408
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
35
Experiment ID 409
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
36
Experiment ID 416
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
37
Experiment ID 834
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
38
Experiment ID 835
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
39
Experiment ID 410
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
40
Experiment ID 217
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for DDX1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CHMP2A 27243
Co-fractionation Homo sapiens
2 HNRNPH1 3187
Co-fractionation Homo sapiens
3 PTPRF 5792
Co-fractionation Homo sapiens
4 RIT1 6016
Negative Genetic Homo sapiens
5 UBE2H 7328
Affinity Capture-MS Homo sapiens
6 LUZP4  
Affinity Capture-MS Homo sapiens
7 ISG15 9636
Affinity Capture-MS Homo sapiens
8 RPL26L1 51121
Co-fractionation Homo sapiens
9 FAM98A 25940
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
10 NDRG1 10397
Affinity Capture-MS Homo sapiens
11 QARS 5859
Co-fractionation Homo sapiens
12 BAG3 9531
Affinity Capture-MS Homo sapiens
13 Fus  
Affinity Capture-MS Mus musculus
14 KIAA1211  
Cross-Linking-MS (XL-MS) Homo sapiens
15 EIF3K 27335
Co-fractionation Homo sapiens
16 RIN3  
Affinity Capture-MS Homo sapiens
17 DYNC1I2 1781
Co-fractionation Homo sapiens
18 RPA2 6118
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
19 EIF2B2 8892
Co-fractionation Homo sapiens
20 FGG 2266
Affinity Capture-MS Homo sapiens
21 ABCF1 23
Co-fractionation Homo sapiens
22 ACTC1 70
Proximity Label-MS Homo sapiens
23 RPL10 6134
Affinity Capture-MS Homo sapiens
24 KIF20A 10112
Affinity Capture-MS Homo sapiens
25 ATM 472
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
26 CAND1 55832
Affinity Capture-MS Homo sapiens
27 ZBTB1  
Affinity Capture-MS Homo sapiens
28 RPS6KB2  
Affinity Capture-MS Homo sapiens
29 SOX2  
Affinity Capture-MS Homo sapiens
30 APP 351
Reconstituted Complex Homo sapiens
31 ILF2 3608
Co-fractionation Homo sapiens
32 MRE11A 4361
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
33 KIAA1429 25962
Affinity Capture-MS Homo sapiens
34 DIMT1 27292
Affinity Capture-MS Homo sapiens
35 UXS1 80146
Affinity Capture-MS Homo sapiens
36 WDR76  
Affinity Capture-MS Homo sapiens
37 TSTA3 7264
Co-fractionation Homo sapiens
38 NMT1 4836
Co-fractionation Homo sapiens
39 B3GNT2 10678
Affinity Capture-MS Homo sapiens
40 STRN 6801
Co-fractionation Homo sapiens
41 UCP3  
Affinity Capture-MS Homo sapiens
42 TGFB1 7040
Affinity Capture-MS Homo sapiens
43 KIF23 9493
Affinity Capture-MS Homo sapiens
44 MCM2 4171
Affinity Capture-MS Homo sapiens
45 NME7 29922
Two-hybrid Homo sapiens
46 DIAPH2  
Co-fractionation Homo sapiens
47 COPS5 10987
Affinity Capture-MS Homo sapiens
48 FBXW7  
Affinity Capture-MS Homo sapiens
49 PRC1 9055
Affinity Capture-MS Homo sapiens
50 FKBP3 2287
Co-fractionation Homo sapiens
51 NPM1 4869
Affinity Capture-MS Homo sapiens
52 SRRM2 23524
Affinity Capture-MS Homo sapiens
53 VASP 7408
Co-fractionation Homo sapiens
54 OBSL1 23363
Affinity Capture-MS Homo sapiens
55 CUL4A 8451
Affinity Capture-MS Homo sapiens
56 KATNAL2 83473
Co-fractionation Homo sapiens
57 ITGA4 3676
Affinity Capture-MS Homo sapiens
58 FAM98B 283742
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
59 KLF4  
Affinity Capture-MS Homo sapiens
60 VCAM1 7412
Affinity Capture-MS Homo sapiens
61 Rpl35 66489
Affinity Capture-MS Mus musculus
62 XYLT2 64132
Affinity Capture-MS Homo sapiens
63 MECP2 4204
Affinity Capture-MS Homo sapiens
64 Eif3a 13669
Affinity Capture-MS Mus musculus
65 CUL1 8454
Affinity Capture-MS Homo sapiens
66 PSPC1 55269
Affinity Capture-MS Homo sapiens
67 RAD50 10111
Affinity Capture-Western Homo sapiens
68 PLS3 5358
Co-fractionation Homo sapiens
69 YAF2  
Affinity Capture-MS Homo sapiens
70 TFRC 7037
Cross-Linking-MS (XL-MS) Homo sapiens
71 EEF1A1 1915
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
72 KIF14 9928
Affinity Capture-MS Homo sapiens
73 DYNC1H1 1778
Co-fractionation Homo sapiens
74 HSPA8 3312
Affinity Capture-MS Homo sapiens
75 POLR1C 9533
Co-fractionation Homo sapiens
76 HEXIM1 10614
Co-fractionation Homo sapiens
77 EDC4 23644
Co-fractionation Homo sapiens
78 XPO1 7514
Co-fractionation Homo sapiens
79 GEMIN5 25929
Co-fractionation Homo sapiens
80 PPP1CA 5499
Co-fractionation Homo sapiens
81 RHOA 387
Co-fractionation Homo sapiens
82 DLD 1738
Affinity Capture-MS Homo sapiens
83 RNF4 6047
Affinity Capture-MS Homo sapiens
84 HSPA1A 3303
Co-fractionation Homo sapiens
85 USP11 8237
Affinity Capture-MS Homo sapiens
86 CUL4B 8450
Affinity Capture-MS Homo sapiens
87 PARK2  
Affinity Capture-MS Homo sapiens
88 FGA 2243
Affinity Capture-MS Homo sapiens
89 CSTF2 1478
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
90 CLNS1A 1207
Affinity Capture-MS Homo sapiens
91 STAU1 6780
Affinity Capture-MS Homo sapiens
92 FGB 2244
Affinity Capture-MS Homo sapiens
93 ANKS6 203286
Affinity Capture-MS Homo sapiens
94 ALDH18A1 5832
Co-fractionation Homo sapiens
95 UBE2I 7329
Co-fractionation Homo sapiens
96 LRRFIP1 9208
Co-fractionation Homo sapiens
97 YAP1 10413
Affinity Capture-MS Homo sapiens
98 PPP1R8 5511
Co-fractionation Homo sapiens
99 DDX5 1655
Co-fractionation Homo sapiens
100 NTRK1 4914
Affinity Capture-MS Homo sapiens
101 NBN 4683
Affinity Capture-Western Homo sapiens
102 IFI16 3428
Affinity Capture-MS Homo sapiens
103 RAD18  
Affinity Capture-MS Homo sapiens
104 RLIM 51132
Affinity Capture-MS Homo sapiens
105 MAEL  
Affinity Capture-MS Homo sapiens
106 YWHAQ 10971
Reconstituted Complex Homo sapiens
107 Mapk13  
Affinity Capture-MS Mus musculus
108 RFC4 5984
Co-fractionation Homo sapiens
109 FAM98C  
Affinity Capture-MS Homo sapiens
110 DHX9 1660
Co-fractionation Homo sapiens
111 HECTD1 25831
Affinity Capture-MS Homo sapiens
112 CUL2 8453
Affinity Capture-MS Homo sapiens
113 EIF4EBP1  
Co-fractionation Homo sapiens
114 RFX3 5991
Affinity Capture-MS Homo sapiens
115 PICALM 8301
Co-fractionation Homo sapiens
116 HDAC5 10014
Affinity Capture-MS Homo sapiens
117 CAPZB 832
Affinity Capture-MS Homo sapiens
118 CEBPA  
Protein-peptide Homo sapiens
119 KDF1  
Affinity Capture-MS Homo sapiens
120 SCARNA22  
Affinity Capture-RNA Homo sapiens
121 TPR 7175
Co-fractionation Homo sapiens
122 RNF168  
Co-fractionation Homo sapiens
123 HNRNPDL 9987
Co-fractionation Homo sapiens
124 ATG16L1 55054
Affinity Capture-MS Homo sapiens
125 HNRNPD 3184
Co-fractionation Homo sapiens
126 TMPO 7112
Affinity Capture-MS Homo sapiens
127 PSMA3 5684
Affinity Capture-MS Homo sapiens
128 C2orf49 79074
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
129 TMED9 54732
Co-fractionation Homo sapiens
130 STRIP1 85369
Co-fractionation Homo sapiens
131 THUMPD1 55623
Co-fractionation Homo sapiens
132 SAP30BP  
Co-fractionation Homo sapiens
133 METTL14  
Affinity Capture-MS Homo sapiens
134 BYSL 705
Affinity Capture-MS Homo sapiens
135 SDHA 6389
Affinity Capture-MS Homo sapiens
136 RC3H2  
Affinity Capture-MS Homo sapiens
137 EIF2S1 1965
Co-fractionation Homo sapiens
138 GLE1 2733
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
139 VDAC2 7417
Cross-Linking-MS (XL-MS) Homo sapiens
140 CTNNB1 1499
Affinity Capture-MS Homo sapiens
141 RFC2 5982
Co-fractionation Homo sapiens
142 PRMT8  
Affinity Capture-MS Homo sapiens
143 Rbm14  
Two-hybrid Mus musculus
144 CUL3 8452
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
145 Fbxl16  
Affinity Capture-MS Mus musculus
146 BTF3 689
Affinity Capture-MS Homo sapiens
147 MCCC1 56922
Co-fractionation Homo sapiens
148 SH3RF2  
Affinity Capture-MS Homo sapiens
149 HNRNPA1 3178
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
150 FUS 2521
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
151 EIF2B3 8891
Co-fractionation Homo sapiens
152 FN1 2335
Affinity Capture-MS Homo sapiens
153 AURKB 9212
Affinity Capture-MS Homo sapiens
154 RANBP9 10048
Co-fractionation Homo sapiens
155 CDK2 1017
Affinity Capture-MS Homo sapiens
156 IGF2BP3 10643
Co-fractionation Homo sapiens
157 DCUN1D1 54165
Affinity Capture-MS Homo sapiens
158 MYC  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
159 RPA3 6119
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
160 YBX3 8531
Co-fractionation Homo sapiens
161 TRIM11  
Affinity Capture-MS Homo sapiens
162 POP1 10940
Co-fractionation Homo sapiens
163 MYCN  
Affinity Capture-MS Homo sapiens
164 SNW1 22938
Affinity Capture-MS Homo sapiens
165 FLII 2314
Co-fractionation Homo sapiens
166 DDRGK1 65992
Affinity Capture-MS Homo sapiens
167 KIAA0368 23392
Co-fractionation Homo sapiens
168 YBX1 4904
Co-fractionation Homo sapiens
169 NELFB 25920
Co-fractionation Homo sapiens
170 NUP133 55746
Co-fractionation Homo sapiens
171 HUWE1 10075
Affinity Capture-MS Homo sapiens
172 RPS16 6217
Affinity Capture-MS Homo sapiens
173 KRT18 3875
Co-fractionation Homo sapiens
174 DHX15 1665
Co-fractionation Homo sapiens
175 EIF3F 8665
Affinity Capture-MS Homo sapiens
176 ARRB2 409
Affinity Capture-MS Homo sapiens
177 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
178 SPOP  
Affinity Capture-MS Homo sapiens
179 HNRNPH2 3188
Affinity Capture-MS Homo sapiens
180 HAS1 3036
Co-fractionation Homo sapiens
181 HDGF 3068
Affinity Capture-MS Homo sapiens
182 ALDH9A1 223
Co-fractionation Homo sapiens
183 TP53 7157
Affinity Capture-MS Homo sapiens
184 WWOX 51741
Affinity Capture-MS Homo sapiens
185 ZEB1  
Affinity Capture-MS Homo sapiens
186 DDX3X 1654
Co-fractionation Homo sapiens
187 HMCN1 83872
Co-fractionation Homo sapiens
188 RPA1 6117
Affinity Capture-MS Homo sapiens
189 LSM14A 26065
Co-fractionation Homo sapiens
190 CUL5 8065
Affinity Capture-MS Homo sapiens
191 PDCD6 10016
Co-fractionation Homo sapiens
192 HNRNPM 4670
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
193 OXSR1 9943
Co-fractionation Homo sapiens
194 PRMT1 3276
Affinity Capture-MS Homo sapiens
195 PLOD1 5351
Co-fractionation Homo sapiens
196 HDAC1 3065
Affinity Capture-MS Homo sapiens
197 EIF4ENIF1 56478
Two-hybrid Homo sapiens
198 SHMT2 6472
Co-fractionation Homo sapiens
199 NUP35 129401
Proximity Label-MS Homo sapiens
200 HNRNPK 3190
Co-purification Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
201 Myh10 77579
Affinity Capture-MS Mus musculus
202 RAVER1 125950
Co-fractionation Homo sapiens
203 ESR1  
Reconstituted Complex Homo sapiens
204 EEF2 1938
Cross-Linking-MS (XL-MS) Homo sapiens
205 UFL1 23376
Affinity Capture-MS Homo sapiens
206 IDE 3416
Co-fractionation Homo sapiens
207 RBM4 5936
Co-fractionation Homo sapiens
208 PLOD3 8985
Co-fractionation Homo sapiens
209 FGFR1OP2  
Co-fractionation Homo sapiens
210 EIF4B 1975
Affinity Capture-MS Homo sapiens
211 RTCB 51493
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
212 TRIP4 9325
Affinity Capture-MS Homo sapiens
213 PYGB 5834
Co-fractionation Homo sapiens
214 TRIM31  
Affinity Capture-MS Homo sapiens
215 Rrbp1  
Affinity Capture-MS Mus musculus
216 RPL27 6155
Co-fractionation Homo sapiens
217 C14orf166 51637
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
218 CUL7 9820
Affinity Capture-MS Homo sapiens
219 KRAS 3845
Synthetic Lethality Homo sapiens
220 HNRNPU 3192
Co-fractionation Homo sapiens
221 C9orf72  
Affinity Capture-MS Homo sapiens
222 RC3H1 149041
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
223 BAG1 573
Affinity Capture-MS Homo sapiens
224 SCARB2 950
Co-fractionation Homo sapiens
225 NEDD8 4738
Affinity Capture-MS Homo sapiens
226 EP300 2033
Affinity Capture-MS Homo sapiens
227 HNRNPA2B1 3181
Co-fractionation Homo sapiens
View the network image/svg+xml
 Pathways in which DDX1 is involved
PathwayEvidenceSource
Metabolism of RNA TAS Reactome
tRNA processing TAS Reactome
tRNA processing in the nucleus TAS Reactome





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