Gene description for SRRM2
Gene name serine/arginine repetitive matrix 2
Gene symbol SRRM2
Other names/aliases 300-KD
CWF21
Cwc21
SRL300
SRm300
Species Homo sapiens
 Database cross references - SRRM2
ExoCarta ExoCarta_23524
Vesiclepedia VP_23524
Entrez Gene 23524
HGNC 16639
MIM 606032
UniProt Q9UQ35  
 SRRM2 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Endothelial cells 26027894    
Foreskin fibroblasts 34108659    
Hepatocellular carcinoma cells 26054723    
Hepatocellular carcinoma cells 26054723    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
T lymphocytes 34108659    
 Gene ontology annotations for SRRM2
Molecular Function
    RNA binding GO:0003723 HDA
    mRNA binding GO:0003729 IBA
    protein binding GO:0005515 IPI
    C2H2 zinc finger domain binding GO:0070742 IDA
Biological Process
    mRNA splicing, via spliceosome GO:0000398 IC
    mRNA splicing, via spliceosome GO:0000398 IDA
Subcellular Localization
    nucleus GO:0005634 IDA
    nucleoplasm GO:0005654 TAS
    Cajal body GO:0015030 IDA
    nuclear speck GO:0016607 IDA
    U2-type precatalytic spliceosome GO:0071005 IDA
    U2-type catalytic step 2 spliceosome GO:0071007 IDA
    catalytic step 2 spliceosome GO:0071013 IDA
 Experiment description of studies that identified SRRM2 in sEVs
1
Experiment ID 489
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 207
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DKO-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
10
Experiment ID 208
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name Dks-8
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
11
Experiment ID 209
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DLD-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
12
Experiment ID 407
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
13
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
14
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
15
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
16
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
17
Experiment ID 226
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule mRNA
Identification method Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
PubMed ID 26027894    
Organism Homo sapiens
Experiment description "Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting"
Authors "Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar"
Journal name Journal of Extracellular Vesicles
Publication year 2015
Sample Endothelial cells
Sample name HMEC-1
Isolation/purification methods Differential ultracentrifugation
Sucrose density gradient
Flotation density 1.10 g/mL
Molecules identified in the study miRNA
Protein
snoRNA
lncRNA
yRNA
snRNA
mRNA
ncRNA
mtRNA
vtRNA
scaRNA
lincRNA
Methods used in the study Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
Western blotting
18
Experiment ID 405
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
19
Experiment ID 235
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
20
Experiment ID 236
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name MHCC97L
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
21
Experiment ID 417
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
22
Experiment ID 411
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
23
Experiment ID 488
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
24
Experiment ID 418
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
25
Experiment ID 413
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
26
Experiment ID 211
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
27
Experiment ID 212
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
28
Experiment ID 406
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
29
Experiment ID 415
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
30
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
31
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
32
Experiment ID 408
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
33
Experiment ID 409
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
34
Experiment ID 416
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
35
Experiment ID 410
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
 Protein-protein interactions for SRRM2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CFAP20 29105
Affinity Capture-MS Homo sapiens
2 HIST2H2BE 8349
Affinity Capture-MS Homo sapiens
3 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
4 SRPK2 6733
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
5 DYNC1I2 1781
Affinity Capture-MS Homo sapiens
6 DDX21 9188
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
7 ACTC1 70
Proximity Label-MS Homo sapiens
8 KIF20A 10112
Affinity Capture-MS Homo sapiens
9 CSNK2A1 1457
Biochemical Activity Homo sapiens
Affinity Capture-MS Homo sapiens
10 PRPF40A 55660
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
11 SEPT2 4735
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
12 SBDS 51119
Co-fractionation Homo sapiens
13 SEPT9 10801
Affinity Capture-MS Homo sapiens
14 DDX23 9416
Proximity Label-MS Homo sapiens
15 WDR76  
Affinity Capture-MS Homo sapiens
16 PRPF40B  
Co-fractionation Homo sapiens
17 KIF23 9493
Affinity Capture-MS Homo sapiens
18 NFKBIL1  
Affinity Capture-MS Homo sapiens
19 CDK2AP1  
Affinity Capture-MS Homo sapiens
20 ZMYND11 10771
Affinity Capture-MS Homo sapiens
21 FBL 2091
Co-fractionation Homo sapiens
22 SEPT8 23176
Affinity Capture-MS Homo sapiens
23 SNRPD3 6634
Affinity Capture-MS Homo sapiens
24 POLR2C 5432
Proximity Label-MS Homo sapiens
25 SFN 2810
Affinity Capture-MS Homo sapiens
26 PSMC1 5700
Affinity Capture-MS Homo sapiens
27 MECP2 4204
Affinity Capture-MS Homo sapiens
28 SLU7  
Affinity Capture-MS Homo sapiens
29 EEF1A1 1915
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
30 MYL6 4637
Affinity Capture-MS Homo sapiens
31 RBMX 27316
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
32 UNK  
Affinity Capture-RNA Homo sapiens
33 Snap29  
Affinity Capture-MS Mus musculus
34 UTP14A 10813
Co-fractionation Homo sapiens
35 MAP1B 4131
Co-fractionation Homo sapiens
36 SRSF3 6428
Affinity Capture-MS Homo sapiens
37 RBM7  
Affinity Capture-MS Homo sapiens
38 MAPRE1 22919
Affinity Capture-MS Homo sapiens
39 HIST1H3E 8353
Affinity Capture-MS Homo sapiens
40 FAM9A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
41 MRPS6  
Affinity Capture-MS Homo sapiens
42 SYNCRIP 10492
Co-fractionation Homo sapiens
43 DBT 1629
Affinity Capture-MS Homo sapiens
44 SRPK3  
Affinity Capture-MS Homo sapiens
45 EN1  
Affinity Capture-MS Homo sapiens
46 DDX39B 7919
Affinity Capture-MS Homo sapiens
47 STAG2 10735
Co-fractionation Homo sapiens
48 SRPK1 6732
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
49 CD3EAP  
Proximity Label-MS Homo sapiens
50 ANLN 54443
Affinity Capture-MS Homo sapiens
51 MEP1A 4224
Affinity Capture-MS Homo sapiens
52 HIST1H2BL 8340
Cross-Linking-MS (XL-MS) Homo sapiens
53 EPB41L1 2036
Affinity Capture-MS Homo sapiens
54 RBM39 9584
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
55 CALR3  
Affinity Capture-MS Homo sapiens
56 LMNB1 4001
Affinity Capture-MS Homo sapiens
57 SIRT7  
Affinity Capture-MS Homo sapiens
58 CD2BP2 10421
Affinity Capture-MS Homo sapiens
59 GRK5 2869
Affinity Capture-MS Homo sapiens
60 CUL3 8452
Affinity Capture-MS Homo sapiens
61 EEF1B2 1933
Affinity Capture-MS Homo sapiens
62 WIBG 84305
Co-fractionation Homo sapiens
63 RBBP4 5928
Affinity Capture-MS Homo sapiens
64 TUBA4A 7277
Affinity Capture-MS Homo sapiens
65 TJP2 9414
Affinity Capture-MS Homo sapiens
66 RPA3 6119
Proximity Label-MS Homo sapiens
67 HSPA1A 3303
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
68 PSMC5 5705
Affinity Capture-MS Homo sapiens
69 ILK 3611
Affinity Capture-MS Homo sapiens
70 PYHIN1  
Affinity Capture-MS Homo sapiens
71 PAIP1 10605
Affinity Capture-MS Homo sapiens
72 YBX1 4904
Affinity Capture-MS Homo sapiens
73 DNAJC28  
Affinity Capture-MS Homo sapiens
74 EAPP  
Affinity Capture-MS Homo sapiens
75 BCAS2 10286
Affinity Capture-MS Homo sapiens
76 PLEC 5339
Affinity Capture-MS Homo sapiens
77 MBD3 53615
Affinity Capture-MS Homo sapiens
78 RBM25 58517
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
79 MDK 4192
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
80 RUVBL2 10856
Affinity Capture-MS Homo sapiens
81 HIST1H2BC 8347
Cross-Linking-MS (XL-MS) Homo sapiens
82 EIF3I 8668
Affinity Capture-MS Homo sapiens
83 PUF60 22827
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
84 EDA  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
85 PIN1 5300
Reconstituted Complex Homo sapiens
86 ALYREF 10189
Co-fractionation Homo sapiens
87 HNRNPL 3191
Affinity Capture-MS Homo sapiens
88 SNRNP70 6625
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
89 ACO2 50
Affinity Capture-MS Homo sapiens
90 SNW1 22938
Affinity Capture-MS Homo sapiens
91 SCP2 6342
Co-fractionation Homo sapiens
92 PSMC4 5704
Affinity Capture-MS Homo sapiens
93 MATN2 4147
Affinity Capture-MS Homo sapiens
94 LUC7L 55692
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
95 HNRNPH1 3187
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
96 OSBPL10  
Affinity Capture-MS Homo sapiens
97 ATG5 9474
Proximity Label-MS Homo sapiens
98 BTF3 689
Affinity Capture-MS Homo sapiens
99 SF3B1 23451
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
100 CHCHD1  
Proximity Label-MS Homo sapiens
101 EIF4A1 1973
Affinity Capture-MS Homo sapiens
102 CAND1 55832
Affinity Capture-MS Homo sapiens
103 SNRPF 6636
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
104 PTPN4  
Affinity Capture-MS Homo sapiens
105 RNPS1 10921
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
106 HIST2H3A 333932
Cross-Linking-MS (XL-MS) Homo sapiens
107 PRC1 9055
Affinity Capture-MS Homo sapiens
108 MRPS23 51649
Affinity Capture-MS Homo sapiens
109 OBSL1 23363
Affinity Capture-MS Homo sapiens
110 C11orf57  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
111 YWHAH 7533
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
112 LARP4B 23185
Affinity Capture-MS Homo sapiens
113 PES1 23481
Affinity Capture-MS Homo sapiens
114 YWHAB 7529
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
115 PTPN3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
116 GTF2I 2969
Affinity Capture-MS Homo sapiens
117 PRPF8 10594
Proximity Label-MS Homo sapiens
Co-fractionation Homo sapiens
118 TRIM26 7726
Affinity Capture-MS Homo sapiens
119 TRA2A 29896
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
120 ACIN1 22985
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
121 SNRNP200 23020
Co-fractionation Homo sapiens
122 CECR1  
Affinity Capture-MS Homo sapiens
123 SNIP1  
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
124 SNRPD1 6632
Affinity Capture-MS Homo sapiens
125 RAD18  
Affinity Capture-MS Homo sapiens
126 LUC7L2 51631
Affinity Capture-MS Homo sapiens
127 LYAR 55646
Affinity Capture-MS Homo sapiens
128 MAGOH 4116
Affinity Capture-MS Homo sapiens
129 PPM1G 5496
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
130 Ksr1  
Affinity Capture-MS Mus musculus
131 CYLD  
Affinity Capture-MS Homo sapiens
132 SNRPB2 6629
Co-fractionation Homo sapiens
133 PPP4R2  
Affinity Capture-MS Homo sapiens
134 NKX2-5  
Affinity Capture-MS Homo sapiens
135 RPS2 6187
Affinity Capture-MS Homo sapiens
136 MTX2 10651
Proximity Label-MS Homo sapiens
137 SRSF5 6430
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
138 EGFR 1956
Affinity Capture-MS Homo sapiens
139 NUAK1  
Affinity Capture-MS Homo sapiens
140 SPTBN1 6711
Affinity Capture-MS Homo sapiens
141 EFTUD2 9343
Affinity Capture-MS Homo sapiens
142 CDK2 1017
Affinity Capture-MS Homo sapiens
143 PIP4K2A 5305
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
144 TADA2A  
Affinity Capture-MS Homo sapiens
145 MYC  
Affinity Capture-MS Homo sapiens
146 VIM 7431
Affinity Capture-MS Homo sapiens
147 EEF1A2 1917
Affinity Capture-MS Homo sapiens
148 ETV3  
Affinity Capture-MS Homo sapiens
149 CUL7 9820
Affinity Capture-MS Homo sapiens
150 DDRGK1 65992
Affinity Capture-MS Homo sapiens
151 NOG 9241
Affinity Capture-MS Homo sapiens
152 LMNA 4000
Affinity Capture-MS Homo sapiens
153 NKAP 79576
Affinity Capture-MS Homo sapiens
154 MTA2 9219
Affinity Capture-MS Homo sapiens
155 EIF3F 8665
Affinity Capture-MS Homo sapiens
156 RNF151  
Affinity Capture-MS Homo sapiens
157 KIF14 9928
Affinity Capture-MS Homo sapiens
158 ILF3 3609
Co-fractionation Homo sapiens
159 FOLR1 2348
Affinity Capture-MS Homo sapiens
160 SNRPA1 6627
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
161 SF3B4 10262
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
162 SQSTM1 8878
Affinity Capture-MS Homo sapiens
163 Numb  
Affinity Capture-MS Mus musculus
164 C1orf35  
Affinity Capture-MS Homo sapiens
165 RPS5 6193
Affinity Capture-MS Homo sapiens
166 HNRNPK 3190
Co-fractionation Homo sapiens
167 ESR1  
Affinity Capture-MS Homo sapiens
168 JAK3 3718
Affinity Capture-MS Homo sapiens
169 EEF1D 1936
Affinity Capture-MS Homo sapiens
170 RPL7A 6130
Affinity Capture-MS Homo sapiens
171 KRAS 3845
Affinity Capture-MS Homo sapiens
172 SH3KBP1 30011
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
173 RNF113A 7737
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
174 ATOH1  
Affinity Capture-MS Homo sapiens
175 ABCF3 55324
Affinity Capture-MS Homo sapiens
176 HNRNPC 3183
Affinity Capture-MS Homo sapiens
177 SLFN11 91607
Affinity Capture-MS Homo sapiens
178 DNAJC8 22826
Affinity Capture-MS Homo sapiens
179 YWHAE 7531
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
180 RPS19 6223
Affinity Capture-MS Homo sapiens
181 SF3B5 83443
Affinity Capture-MS Homo sapiens
182 HNRNPUL2 221092
Affinity Capture-MS Homo sapiens
183 GSPT2 23708
Affinity Capture-MS Homo sapiens
184 DENND2D  
Affinity Capture-MS Homo sapiens
185 PFKFB2 5208
Affinity Capture-MS Homo sapiens
186 EIF3B 8662
Affinity Capture-MS Homo sapiens
187 CDK12 51755
Affinity Capture-MS Homo sapiens
188 IQGAP1 8826
Affinity Capture-MS Homo sapiens
189 MCM6 4175
Affinity Capture-MS Homo sapiens
190 SF3A2 8175
Affinity Capture-MS Homo sapiens
191 SRP14 6727
Co-fractionation Homo sapiens
192 RBM8A 9939
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
193 HSPA8 3312
Affinity Capture-MS Homo sapiens
194 EPB41L3 23136
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
195 NF2 4771
Affinity Capture-MS Homo sapiens
196 CLK2 1196
Affinity Capture-MS Homo sapiens
197 CLK4  
Affinity Capture-MS Homo sapiens
198 CBX3 11335
Proximity Label-MS Homo sapiens
199 SRRM1 10250
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
200 PARK2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
201 PPIL1 51645
Affinity Capture-MS Homo sapiens
202 XRN1 54464
Two-hybrid Homo sapiens
203 RTF1 23168
Co-fractionation Homo sapiens
204 ZCCHC17  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
205 CHMP4B 128866
Affinity Capture-MS Homo sapiens
206 BARD1 580
Affinity Capture-MS Homo sapiens
207 NTRK1 4914
Affinity Capture-MS Homo sapiens
208 U2AF2 11338
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
209 GATA4  
Affinity Capture-MS Homo sapiens
210 DNAJA1 3301
Affinity Capture-MS Homo sapiens
211 DHX9 1660
Co-fractionation Homo sapiens
212 EIF3H 8667
Affinity Capture-MS Homo sapiens
213 YAP1 10413
Affinity Capture-MS Homo sapiens
214 HNRNPA3 220988
Co-fractionation Homo sapiens
215 RBBP6 5930
Affinity Capture-MS Homo sapiens
216 SF3B2 10992
Affinity Capture-MS Homo sapiens
217 USP42  
Affinity Capture-MS Homo sapiens
218 CDC73  
Co-fractionation Homo sapiens
219 BAZ1B 9031
Co-fractionation Homo sapiens
220 BAG2 9532
Affinity Capture-MS Homo sapiens
221 ECT2 1894
Affinity Capture-MS Homo sapiens
222 EPPK1 83481
Affinity Capture-MS Homo sapiens
223 DNAJC17  
Affinity Capture-MS Homo sapiens
224 HNRNPA1 3178
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
225 DNAJC25 548645
Affinity Capture-MS Homo sapiens
226 SOX15  
Affinity Capture-MS Homo sapiens
227 PRPF19 27339
Affinity Capture-MS Homo sapiens
228 RPS13 6207
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
229 ZC3H18  
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
230 TERF2  
Affinity Capture-MS Homo sapiens
231 DHPS 1725
Affinity Capture-MS Homo sapiens
232 TOP1 7150
Affinity Capture-MS Homo sapiens
233 RPL22 6146
Affinity Capture-MS Homo sapiens
234 SEPT7 989
Affinity Capture-MS Homo sapiens
235 HSPD1 3329
Affinity Capture-MS Homo sapiens
236 DDX50 79009
Affinity Capture-MS Homo sapiens
237 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
238 RPL6 6128
Co-fractionation Homo sapiens
239 AKAP17A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
240 DDX3X 1654
Affinity Capture-MS Homo sapiens
241 SON 6651
Co-fractionation Homo sapiens
242 MEN1 4221
Affinity Capture-MS Homo sapiens
243 SNRPA 6626
Affinity Capture-MS Homo sapiens
244 HNRNPM 4670
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
245 NHLRC2 374354
Affinity Capture-MS Homo sapiens
246 HSPB1 3315
Affinity Capture-MS Homo sapiens
247 THOC6 79228
Co-fractionation Homo sapiens
248 DDX58 23586
Affinity Capture-RNA Homo sapiens
249 UFL1 23376
Affinity Capture-MS Homo sapiens
250 BAK1 578
Affinity Capture-MS Homo sapiens
251 SRRM3  
Negative Genetic Homo sapiens
252 API5 8539
Affinity Capture-MS Homo sapiens
253 HNRNPH3 3189
Affinity Capture-MS Homo sapiens
254 FLNA 2316
Co-fractionation Homo sapiens
255 PGK1 5230
Cross-Linking-MS (XL-MS) Homo sapiens
256 RPS7 6201
Affinity Capture-MS Homo sapiens
257 HNRNPF 3185
Affinity Capture-MS Homo sapiens
258 RC3H1 149041
Affinity Capture-MS Homo sapiens
259 SSRP1 6749
Affinity Capture-MS Homo sapiens
260 EP300 2033
Affinity Capture-MS Homo sapiens
261 UBE2H 7328
Affinity Capture-MS Homo sapiens
262 CAMKV 79012
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
263 RSBN1L  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
264 DSN1 79980
Negative Genetic Homo sapiens
265 PAXIP1  
Affinity Capture-MS Homo sapiens
266 RPS3A 6189
Affinity Capture-MS Homo sapiens
267 PPIE 10450
Affinity Capture-MS Homo sapiens
268 USP5 8078
Cross-Linking-MS (XL-MS) Homo sapiens
269 SUB1 10923
Co-fractionation Homo sapiens
270 DHX8 1659
Proximity Label-MS Homo sapiens
271 PRPF3  
Co-fractionation Homo sapiens
272 ELAVL1 1994
Affinity Capture-MS Homo sapiens
273 SNRPD2 6633
Affinity Capture-MS Homo sapiens
274 APP 351
Reconstituted Complex Homo sapiens
275 TMPO 7112
Affinity Capture-MS Homo sapiens
276 ILF2 3608
Co-fractionation Homo sapiens
277 GSK3A 2931
Affinity Capture-MS Homo sapiens
278 SULF2 55959
Affinity Capture-MS Homo sapiens
279 TGFB1 7040
Affinity Capture-MS Homo sapiens
280 HSPA5 3309
Co-fractionation Homo sapiens
281 NDUFA7 4701
Co-fractionation Homo sapiens
282 COPS5 10987
Affinity Capture-MS Homo sapiens
283 MRPL12 6182
Affinity Capture-MS Homo sapiens
284 SNRPC 6631
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
285 YWHAG 7532
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
286 ABCE1 6059
Affinity Capture-MS Homo sapiens
287 HINFP  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
288 EED  
Affinity Capture-MS Homo sapiens
289 DDX41 51428
Affinity Capture-MS Homo sapiens
290 MYCN  
Affinity Capture-MS Homo sapiens
291 PRPF6 24148
Co-fractionation Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
292 POLD1 5424
Affinity Capture-MS Homo sapiens
293 NONO 4841
Affinity Capture-MS Homo sapiens
294 CCT5 22948
Affinity Capture-MS Homo sapiens
295 SRSF6 6431
Affinity Capture-MS Homo sapiens
296 SRSF4 6429
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
297 VCP 7415
Affinity Capture-MS Homo sapiens
298 DDX5 1655
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
299 IFI16 3428
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
300 XAGE1B  
Affinity Capture-MS Homo sapiens
301 DDX1 1653
Affinity Capture-MS Homo sapiens
302 SARNP 84324
Co-fractionation Homo sapiens
303 CEBPA  
Protein-peptide Homo sapiens
304 DAXX  
Affinity Capture-MS Homo sapiens
305 U2AF1 7307
Co-fractionation Homo sapiens
306 ELAVL2 1993
Affinity Capture-MS Homo sapiens
307 SRSF11 9295
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
308 SFPQ 6421
Affinity Capture-MS Homo sapiens
309 PRPF4B 8899
Affinity Capture-MS Homo sapiens
310 FANCD2  
Affinity Capture-MS Homo sapiens
311 CLK3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
312 PINK1  
Affinity Capture-MS Homo sapiens
313 PNN 5411
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
314 SNRPB 6628
Affinity Capture-MS Homo sapiens
315 CTNNB1 1499
Affinity Capture-MS Homo sapiens
316 SRSF1 6426
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
317 SART1 9092
Co-fractionation Homo sapiens
318 SF3A1 10291
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
319 Ezr 22350
Affinity Capture-MS Mus musculus
320 GTF3C6  
Affinity Capture-MS Homo sapiens
321 MYO6 4646
Proximity Label-MS Homo sapiens
322 RASSF10  
Affinity Capture-MS Homo sapiens
323 PABPC5 140886
Affinity Capture-MS Homo sapiens
324 FIP1L1 81608
Affinity Capture-MS Homo sapiens
325 SF3B3 23450
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
326 BMP4 652
Affinity Capture-MS Homo sapiens
327 BRD3 8019
Affinity Capture-MS Homo sapiens
328 DHX15 1665
Co-fractionation Homo sapiens
329 ARRB2 409
Affinity Capture-MS Homo sapiens
330 PPP4C 5531
Affinity Capture-MS Homo sapiens
331 ZRANB2 9406
Affinity Capture-MS Homo sapiens
332 CPSF6 11052
Affinity Capture-MS Homo sapiens
333 PRNP 5621
Affinity Capture-MS Homo sapiens
334 SMARCC1 6599
Affinity Capture-MS Homo sapiens
335 SAP18 10284
Affinity Capture-MS Homo sapiens
336 HNRNPA2B1 3181
Affinity Capture-MS Homo sapiens
337 TTC14  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
338 RPS15 6209
Cross-Linking-MS (XL-MS) Homo sapiens
339 PDHB 5162
Affinity Capture-MS Homo sapiens
340 HIST1H2BD 3017
Cross-Linking-MS (XL-MS) Homo sapiens
341 EIF4A3 9775
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
342 EPB41L2 2037
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
343 NUP50 10762
Proximity Label-MS Homo sapiens
344 DHX16 8449
Affinity Capture-MS Homo sapiens
345 SREK1IP1  
Affinity Capture-MS Homo sapiens
346 ARRB1 408
Affinity Capture-MS Homo sapiens
347 TRIP4 9325
Affinity Capture-MS Homo sapiens
348 AIRE  
Affinity Capture-MS Homo sapiens
349 SRSF7 6432
Affinity Capture-MS Homo sapiens
350 ZCCHC10  
Affinity Capture-MS Homo sapiens
351 XRCC6 2547
Affinity Capture-MS Homo sapiens
352 DNAJC1 64215
Affinity Capture-MS Homo sapiens
353 HNRNPU 3192
Co-fractionation Homo sapiens
354 CDC5L 988
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here