Gene ontology annotations for VIM
Experiment description of studies that identified VIM in sEVs
1
Experiment ID
79
MISEV standards
✘
Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
20458337
Organism
Homo sapiens
Experiment description
MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 1
Authors
"Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name
ICB
Publication year
2010
Sample
B cells
Sample name
RN (HLA-DR15)
Isolation/purification methods
Differential centrifugation Sucrose density gradient Immunobeads (MHC Class II)
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry [FT-ICR] Western blotting
2
Experiment ID
80
MISEV standards
✘
Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
20458337
Organism
Homo sapiens
Experiment description
MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis -Sample 2
Authors
"Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name
ICB
Publication year
2010
Sample
B cells
Sample name
RN (HLA-DR15)
Isolation/purification methods
Differential centrifugation Sucrose density gradient Immunobeads (MHC Class II)
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry [FT-ICR] Western blotting
3
Experiment ID
81
MISEV standards
✘
Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
20458337
Organism
Homo sapiens
Experiment description
MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 3
Authors
"Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name
ICB
Publication year
2010
Sample
B cells
Sample name
RN (HLA-DR15)
Isolation/purification methods
Differential centrifugation Sucrose density gradient Immunobeads (MHC Class II)
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry [FT-ICR] Western blotting
4
Experiment ID
489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Rattus norvegicus
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Bone marrow mesenchymal stem cells
Sample name
BMSC - Passage 6
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
5
Experiment ID
490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Rattus norvegicus
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Bone marrow mesenchymal stem cells
Sample name
BMSC - Passage 7
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
6
Experiment ID
491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Rattus norvegicus
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Bone marrow mesenchymal stem cells
Sample name
BMSC - Passage 8
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
7
Experiment ID
492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Rattus norvegicus
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Bone marrow mesenchymal stem cells
Sample name
BMSC - Passage 9
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
8
Experiment ID
412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Breast cancer cells
Sample name
MCF7
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein mRNA
Methods used in the study
RT-qPCR Western blotting Mass spectrometry Flow cytometry
9
Experiment ID
414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Breast cancer cells
Sample name
MDA-MB-231
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein mRNA
Methods used in the study
RT-qPCR Western blotting Mass spectrometry Flow cytometry
10
Experiment ID
426
MISEV standards
✘
Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Breast cancer cells
Sample name
MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Size exclusion chromatography
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
11
Experiment ID
427
MISEV standards
✘
Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Breast cancer cells
Sample name
MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
12
Experiment ID
494
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD151|CD63|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
✘
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
35931686
Organism
Homo sapiens
Experiment description
Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors
"Varela-EirÃÂn M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, GarcÃÂa-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name
Cell Death Dis
Publication year
2022
Sample
Chondrocytes
Sample name
Osteoarthritic cartilage
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
13
Experiment ID
496
MISEV standards
✘
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
✘
Negative markers
✘
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
35931686
Organism
Homo sapiens
Experiment description
Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors
"Varela-EirÃÂn M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, GarcÃÂa-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name
Cell Death Dis
Publication year
2022
Sample
Chondrocytes
Sample name
Healthy cartilage
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
14
Experiment ID
497
MISEV standards
✘
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
35931686
Organism
Homo sapiens
Experiment description
Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors
"Varela-EirÃÂn M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, GarcÃÂa-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name
Cell Death Dis
Publication year
2022
Sample
Chondrocytes
Sample name
T/C-28a2
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
15
Experiment ID
498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
35931686
Organism
Homo sapiens
Experiment description
Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors
"Varela-EirÃÂn M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, GarcÃÂa-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name
Cell Death Dis
Publication year
2022
Sample
Chondrocytes
Sample name
T/C-28a2
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
16
Experiment ID
407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Embryonic kidney cells
Sample name
HEK293T
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein mRNA
Methods used in the study
RT-qPCR Western blotting Mass spectrometry Flow cytometry
17
Experiment ID
419
MISEV standards
✘
Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Embryonic kidney cells
Sample name
HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Size exclusion chromatography
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
18
Experiment ID
419
MISEV standards
✘
Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Embryonic kidney cells
Sample name
HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Size exclusion chromatography
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
19
Experiment ID
420
MISEV standards
✘
Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Embryonic kidney cells
Sample name
HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
20
Experiment ID
420
MISEV standards
✘
Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Embryonic kidney cells
Sample name
HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
21
Experiment ID
405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Foreskin fibroblasts
Sample name
BJ
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein mRNA
Methods used in the study
RT-qPCR Western blotting Mass spectrometry Flow cytometry
22
Experiment ID
363
MISEV standards
✘
Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
33991177
Organism
Homo sapiens
Experiment description
Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors
"Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name
Proteomics
Publication year
2021
Sample
Gastric cancer cells
Sample name
MKN1 - 100K pellet
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
23
Experiment ID
364
MISEV standards
✘
Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
33991177
Organism
Homo sapiens
Experiment description
Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors
"Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name
Proteomics
Publication year
2021
Sample
Gastric cancer cells
Sample name
MKN1 - 100K pellet
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
24
Experiment ID
365
MISEV standards
✘
Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
33991177
Organism
Homo sapiens
Experiment description
Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors
"Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name
Proteomics
Publication year
2021
Sample
Gastric cancer cells
Sample name
MKN1 - 100K pellet
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
25
Experiment ID
234
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule
mRNA
Identification method
RNA Sequencing
PubMed ID
26054723
Organism
Homo sapiens
Experiment description
Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors
"He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name
Carcinogenesis
Publication year
2015
Sample
Hepatocellular carcinoma cells
Sample name
HKCI-C3
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient
Flotation density
1.13-1.19 g/mL
Molecules identified in the study
Protein RNA
Methods used in the study
Western blotting Mass spectrometry RT-PCR RNA Sequencing
26
Experiment ID
235
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule
mRNA
Identification method
RNA Sequencing
PubMed ID
26054723
Organism
Homo sapiens
Experiment description
Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors
"He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name
Carcinogenesis
Publication year
2015
Sample
Hepatocellular carcinoma cells
Sample name
HKCI-8
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient
Flotation density
1.13-1.19 g/mL
Molecules identified in the study
Protein RNA
Methods used in the study
Western blotting Mass spectrometry RT-PCR RNA Sequencing
27
Experiment ID
236
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule
mRNA
Identification method
RNA Sequencing
PubMed ID
26054723
Organism
Homo sapiens
Experiment description
Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors
"He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name
Carcinogenesis
Publication year
2015
Sample
Hepatocellular carcinoma cells
Sample name
MHCC97L
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient
Flotation density
1.13-1.19 g/mL
Molecules identified in the study
Protein RNA
Methods used in the study
Western blotting Mass spectrometry RT-PCR RNA Sequencing
28
Experiment ID
267
MISEV standards
✘
Biophysical techniques
✔
TSG101|Alix
Enriched markers
✔
CANX|HSP90B1
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
25265333
Organism
Homo sapiens
Experiment description
Quantitative Proteomic Analysis of Exosome Protein Content Changes Induced by Hepatitis B Virus in Huh-7 Cells Using SILAC Labeling and LC-MS/MS
Authors
"Zhao X, Wu Y, Duan J, Ma Y, Shen Z, Wei L, Cui X, Zhang J, Xie Y, Liu J"
Journal name
J Proteome Res
Publication year
2014
Sample
Liver cancer cells
Sample name
Huh-7 - Transfected with HBx plasmids
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
29
Experiment ID
417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Lymphoma cells
Sample name
Raji
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein mRNA
Methods used in the study
RT-qPCR Western blotting Mass spectrometry Flow cytometry
30
Experiment ID
411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Mammary cancer-associated fibroblasts
Sample name
mCAF
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein mRNA
Methods used in the study
RT-qPCR Western blotting Mass spectrometry Flow cytometry
31
Experiment ID
254
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Western blotting
PubMed ID
25950383
Organism
Homo sapiens
Experiment description
Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors
"Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name
Pigment Cell Melanoma Res
Publication year
2015
Sample
Melanoma cells
Sample name
MNT-1
Isolation/purification methods
Differential centrifugation Unltracentrifugation Sucrose density gradient
Flotation density
1.13 - 1.19 g/mL
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
32
Experiment ID
254
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Western blotting
PubMed ID
25950383
Organism
Homo sapiens
Experiment description
Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors
"Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name
Pigment Cell Melanoma Res
Publication year
2015
Sample
Melanoma cells
Sample name
MNT-1
Isolation/purification methods
Differential centrifugation Unltracentrifugation Sucrose density gradient
Flotation density
1.13 - 1.19 g/mL
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
33
Experiment ID
256
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Western blotting
PubMed ID
25950383
Organism
Homo sapiens
Experiment description
Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors
"Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name
Pigment Cell Melanoma Res
Publication year
2015
Sample
Melanoma cells
Sample name
501mel
Isolation/purification methods
Differential centrifugation Unltracentrifugation Sucrose density gradient
Flotation density
1.13 - 1.19 g/mL
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
34
Experiment ID
257
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Western blotting
PubMed ID
25950383
Organism
Homo sapiens
Experiment description
Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors
"Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name
Pigment Cell Melanoma Res
Publication year
2015
Sample
Melanoma cells
Sample name
Daju
Isolation/purification methods
Differential centrifugation Unltracentrifugation Sucrose density gradient
Flotation density
1.13 - 1.19 g/mL
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
35
Experiment ID
258
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Western blotting
PubMed ID
25950383
Organism
Homo sapiens
Experiment description
Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors
"Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name
Pigment Cell Melanoma Res
Publication year
2015
Sample
Melanoma cells
Sample name
SKMEL28
Isolation/purification methods
Differential centrifugation Unltracentrifugation Sucrose density gradient
Flotation density
1.13 - 1.19 g/mL
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
36
Experiment ID
259
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Western blotting
PubMed ID
25950383
Organism
Homo sapiens
Experiment description
Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors
"Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name
Pigment Cell Melanoma Res
Publication year
2015
Sample
Melanoma cells
Sample name
A375M
Isolation/purification methods
Differential centrifugation Unltracentrifugation Sucrose density gradient
Flotation density
1.13 - 1.19 g/mL
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
37
Experiment ID
260
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Western blotting
PubMed ID
25950383
Organism
Homo sapiens
Experiment description
Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors
"Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name
Pigment Cell Melanoma Res
Publication year
2015
Sample
Melanoma cells
Sample name
1205Lu
Isolation/purification methods
Differential centrifugation Unltracentrifugation Sucrose density gradient
Flotation density
1.13 - 1.19 g/mL
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
38
Experiment ID
126
MISEV standards
✘
Biophysical techniques
✔
GAPDH
Enriched markers
✘
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry [LTQ-FT Ultra]
PubMed ID
Unpublished / Not applicable
Organism
Homo sapiens
Experiment description
Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors
"Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim"
Journal name
Mesenchymal Stem Cell Therapy
Publication year
2011
Sample
Mesenchymal stem cells
Sample name
huES9.E1
Isolation/purification methods
HPLC
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Antobody array Mass spectrometry
39
Experiment ID
488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Homo sapiens
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Mesenchymal stem cells
Sample name
UCMSC
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
40
Experiment ID
418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Monocytic leukemia cells
Sample name
THP-1
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein mRNA
Methods used in the study
RT-qPCR Western blotting Mass spectrometry Flow cytometry
41
Experiment ID
219
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|CD9
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
25857718
Organism
Homo sapiens
Experiment description
Proteomic analysis of exosomes from nasopharyngeal carcinoma cell identifies intercellular transfer of angiogenic proteins
Authors
"Chan YK, Zhang H, Liu P, Tsao GS, Li Lung M, Mak NK, Ngok-Shun Wong R, Ying-Kit Yue P"
Journal name
Int J Cancer
Publication year
2015
Sample
Nasopharyngeal carcinoma cells
Sample name
C666-1
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient
Flotation density
1.17-1.19 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
42
Experiment ID
220
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|CD9
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
25857718
Organism
Homo sapiens
Experiment description
Proteomic analysis of exosomes from nasopharyngeal carcinoma cell identifies intercellular transfer of angiogenic proteins
Authors
"Chan YK, Zhang H, Liu P, Tsao GS, Li Lung M, Mak NK, Ngok-Shun Wong R, Ying-Kit Yue P"
Journal name
Int J Cancer
Publication year
2015
Sample
Nasopharyngeal carcinoma cells
Sample name
NP69
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient
Flotation density
1.17-1.19 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
43
Experiment ID
221
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|CD9
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
25857718
Organism
Homo sapiens
Experiment description
Proteomic analysis of exosomes from nasopharyngeal carcinoma cell identifies intercellular transfer of angiogenic proteins
Authors
"Chan YK, Zhang H, Liu P, Tsao GS, Li Lung M, Mak NK, Ngok-Shun Wong R, Ying-Kit Yue P"
Journal name
Int J Cancer
Publication year
2015
Sample
Nasopharyngeal carcinoma cells
Sample name
NP460
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient
Flotation density
1.17-1.19 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
44
Experiment ID
413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Normal mammary epithelial cells
Sample name
MCF10A
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein mRNA
Methods used in the study
RT-qPCR Western blotting Mass spectrometry Flow cytometry
45
Experiment ID
211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23333927
Organism
Homo sapiens
Experiment description
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors
"Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name
J Proteomics
Publication year
2013
Sample
Ovarian cancer cells
Sample name
IGROV1
Isolation/purification methods
Differential centrifugation Ultracentrifugation Sucrose density gradient
Flotation density
1.09-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
46
Experiment ID
212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23333927
Organism
Homo sapiens
Experiment description
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors
"Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name
J Proteomics
Publication year
2013
Sample
Ovarian cancer cells
Sample name
OVCAR-3
Isolation/purification methods
Differential centrifugation Ultracentrifugation Sucrose density gradient
Flotation density
1.09-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
47
Experiment ID
406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Pancreatic cancer cells
Sample name
BxPC3
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein mRNA
Methods used in the study
RT-qPCR Western blotting Mass spectrometry Flow cytometry
48
Experiment ID
415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Pancreatic cancer cells
Sample name
PANC-1
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein mRNA
Methods used in the study
RT-qPCR Western blotting Mass spectrometry Flow cytometry
49
Experiment ID
434
MISEV standards
✘
Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Pancreatic cancer cells
Sample name
PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Size exclusion chromatography
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
50
Experiment ID
435
MISEV standards
✘
Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Pancreatic cancer cells
Sample name
PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
51
Experiment ID
408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Pancreatic duct epithalial cells
Sample name
HPDE
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein mRNA
Methods used in the study
RT-qPCR Western blotting Mass spectrometry Flow cytometry
52
Experiment ID
409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Pancreatic duct epithalial cells
Sample name
HPNE
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein mRNA
Methods used in the study
RT-qPCR Western blotting Mass spectrometry Flow cytometry
53
Experiment ID
416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Pluripotent stem cells
Sample name
PSC
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein mRNA
Methods used in the study
RT-qPCR Western blotting Mass spectrometry Flow cytometry
54
Experiment ID
275
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
25844599
Organism
Homo sapiens
Experiment description
Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors
"Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name
Oncotarget
Publication year
2015
Sample
Prostate cancer cells
Sample name
DU145 - Docetaxel sensitive
Isolation/purification methods
Filtration Ultracentrifugation Sucrose density gradient
Flotation density
1.12-1.19 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry/Flow cytometry/Western blotting
55
Experiment ID
834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
35333565
Organism
Homo sapiens
Experiment description
LAMP2A regulates the loading of proteins into exosomes
Authors
"Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name
Sci Adv
Publication year
2022
Sample
Retinal pigment epithelial cells
Sample name
ARPE-19
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
56
Experiment ID
835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
35333565
Organism
Homo sapiens
Experiment description
LAMP2A regulates the loading of proteins into exosomes
Authors
"Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name
Sci Adv
Publication year
2022
Sample
Retinal pigment epithelial cells
Sample name
ARPE-19
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
57
Experiment ID
410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
T lymphocytes
Sample name
Jurkat
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein mRNA
Methods used in the study
RT-qPCR Western blotting Mass spectrometry Flow cytometry
58
Experiment ID
217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23844026
Organism
Homo sapiens
Experiment description
Characterization of human thymic exosomes.
Authors
"Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name
PLoS One
Publication year
2013
Sample
Thymus
Sample name
Normal-Thymus
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
Protein-protein interactions for VIM
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
TGOLN2
10618
Affinity Capture-MS
Homo sapiens
2
ISG15
9636
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
3
KRT76
51350
Cross-Linking-MS (XL-MS)
Homo sapiens
4
DGCR14
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
5
KRT1
3848
Cross-Linking-MS (XL-MS)
Homo sapiens
6
RIN3
Affinity Capture-MS
Homo sapiens
7
PKP2
5318
Two-hybrid
Homo sapiens
8
KRT6A
3853
Cross-Linking-MS (XL-MS)
Homo sapiens
9
GADD45A
Two-hybrid
Homo sapiens
10
CDH5
Affinity Capture-Western
Homo sapiens
11
GLB1
2720
Affinity Capture-MS
Homo sapiens
12
KIF20A
10112
Affinity Capture-MS
Homo sapiens
13
THOC7
80145
Co-fractionation
Homo sapiens
14
KPNA2
3838
Co-fractionation
Homo sapiens
15
SLC27A6
Two-hybrid
Homo sapiens
16
ATN1
Two-hybrid
Homo sapiens
17
RNF208
Affinity Capture-MS
Homo sapiens
Affinity Capture-Western
Homo sapiens
18
PRKDC
5591
Co-fractionation
Homo sapiens
19
EFNA3
Affinity Capture-MS
Homo sapiens
20
DPPA4
Two-hybrid
Homo sapiens
21
PPL
5493
Two-hybrid
Homo sapiens
Affinity Capture-Western
Homo sapiens
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
Affinity Capture-Western
Homo sapiens
22
PSMC5
5705
Two-hybrid
Homo sapiens
23
WDR76
Affinity Capture-MS
Homo sapiens
24
STX1A
6804
Two-hybrid
Homo sapiens
25
KIF23
9493
Affinity Capture-MS
Homo sapiens
26
GNS
2799
Co-fractionation
Homo sapiens
27
TRIOBP
11078
Two-hybrid
Homo sapiens
28
EGFL8
Affinity Capture-MS
Homo sapiens
29
PIAS4
Two-hybrid
Homo sapiens
30
CALD1
800
Affinity Capture-MS
Homo sapiens
31
SLC9A9
285195
Affinity Capture-MS
Homo sapiens
32
ASB9
Affinity Capture-MS
Homo sapiens
33
HMG20B
Two-hybrid
Homo sapiens
Co-fractionation
Homo sapiens
34
MECP2
4204
Affinity Capture-MS
Homo sapiens
35
WBP2
23558
Affinity Capture-MS
Homo sapiens
36
ALS2CR11
Two-hybrid
Homo sapiens
37
RAD23A
5886
Affinity Capture-Western
Homo sapiens
38
DYNLT1
6993
Affinity Capture-MS
Homo sapiens
39
KIF14
9928
Affinity Capture-MS
Homo sapiens
40
AKT1
207
Affinity Capture-MS
Homo sapiens
Affinity Capture-Western
Homo sapiens
Biochemical Activity
Homo sapiens
Reconstituted Complex
Homo sapiens
41
XRCC4
Two-hybrid
Homo sapiens
42
PPM1B
5495
Affinity Capture-MS
Homo sapiens
43
ANXA7
310
Two-hybrid
Homo sapiens
44
UTP14A
10813
Two-hybrid
Homo sapiens
45
RNF4
6047
Affinity Capture-MS
Homo sapiens
46
USP14
9097
Affinity Capture-Western
Homo sapiens
Affinity Capture-Western
Homo sapiens
47
FOXK1
221937
Co-fractionation
Homo sapiens
48
RRP9
9136
Co-fractionation
Homo sapiens
49
PSME1
5720
Two-hybrid
Homo sapiens
50
NOD2
64127
Two-hybrid
Homo sapiens
Affinity Capture-Western
Homo sapiens
51
MAPRE1
22919
Affinity Capture-MS
Homo sapiens
52
PNMA5
114824
Two-hybrid
Homo sapiens
53
CERS2
29956
Affinity Capture-MS
Homo sapiens
54
YAP1
10413
Affinity Capture-MS
Homo sapiens
55
MAN2A2
4122
Two-hybrid
Homo sapiens
56
SLX4
Affinity Capture-MS
Homo sapiens
57
TCHP
Two-hybrid
Homo sapiens
58
YWHAQ
10971
Affinity Capture-MS
Homo sapiens
Reconstituted Complex
Homo sapiens
Co-fractionation
Homo sapiens
59
CAPN1
823
Affinity Capture-MS
Homo sapiens
60
BRAP
Co-fractionation
Homo sapiens
61
ZYG11B
Affinity Capture-MS
Homo sapiens
62
MGMT
4255
Affinity Capture-MS
Homo sapiens
63
TXN2
25828
Two-hybrid
Homo sapiens
64
SCARNA22
Affinity Capture-RNA
Homo sapiens
65
ANLN
54443
Affinity Capture-MS
Homo sapiens
66
HSPA5
3309
Affinity Capture-MS
Homo sapiens
67
AHSA1
10598
Affinity Capture-MS
Homo sapiens
68
HTRA2
27429
Protein-peptide
Homo sapiens
Biochemical Activity
Homo sapiens
69
KIF15
56992
Two-hybrid
Homo sapiens
70
AGPAT1
10554
Affinity Capture-MS
Homo sapiens
71
PLA2G4A
5321
Affinity Capture-Western
Homo sapiens
72
LMNB1
4001
Affinity Capture-MS
Homo sapiens
Affinity Capture-Western
Homo sapiens
73
SH3YL1
Two-hybrid
Homo sapiens
74
PRMT8
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
75
NES
10763
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
76
ATP6AP2
10159
Affinity Capture-MS
Homo sapiens
77
DES
1674
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
78
BHLHE40
Two-hybrid
Homo sapiens
79
LOR
Two-hybrid
Homo sapiens
80
FN1
2335
Affinity Capture-MS
Homo sapiens
81
PPHLN1
Two-hybrid
Homo sapiens
82
KRT15
3866
Cross-Linking-MS (XL-MS)
Homo sapiens
83
UBR1
197131
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
84
RPA3
6119
Proximity Label-MS
Homo sapiens
85
SIK1
Affinity Capture-MS
Homo sapiens
86
AHR
196
Affinity Capture-Western
Homo sapiens
Affinity Capture-Western
Homo sapiens
87
ING5
Two-hybrid
Homo sapiens
88
GXYLT1
283464
Affinity Capture-MS
Homo sapiens
89
NCF1
Affinity Capture-MS
Homo sapiens
90
KRT19
3880
Proximity Label-MS
Homo sapiens
Cross-Linking-MS (XL-MS)
Homo sapiens
91
NFATC2
Two-hybrid
Homo sapiens
92
TNNT1
Two-hybrid
Homo sapiens
93
UROD
7389
Two-hybrid
Homo sapiens
94
PSMB2
5690
Co-fractionation
Homo sapiens
95
CPEB4
Affinity Capture-MS
Homo sapiens
Affinity Capture-Western
Homo sapiens
Affinity Capture-Western
Homo sapiens
Co-localization
Homo sapiens
96
NUDT21
11051
Co-fractionation
Homo sapiens
97
GRB2
2885
Two-hybrid
Homo sapiens
98
KRT84
3890
Cross-Linking-MS (XL-MS)
Homo sapiens
99
PLEC
5339
Reconstituted Complex
Homo sapiens
Affinity Capture-Western
Homo sapiens
100
URGCP
55665
Co-fractionation
Homo sapiens
101
FABP4
2167
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
102
MTA1
9112
Affinity Capture-MS
Homo sapiens
103
PSMB7
5695
Co-fractionation
Homo sapiens
104
THOC3
Co-fractionation
Homo sapiens
105
SEPT9
10801
Affinity Capture-MS
Homo sapiens
106
CWF19L2
Two-hybrid
Homo sapiens
107
KRT72
140807
Cross-Linking-MS (XL-MS)
Homo sapiens
108
HSP90AA1
3320
Affinity Capture-Western
Homo sapiens
Affinity Capture-Western
Homo sapiens
109
PUF60
22827
Two-hybrid
Homo sapiens
110
PSMA1
5682
Two-hybrid
Homo sapiens
Co-fractionation
Homo sapiens
111
TSC22D1
8848
Two-hybrid
Homo sapiens
112
KLK10
5655
Affinity Capture-MS
Homo sapiens
113
AIMP2
7965
Affinity Capture-MS
Homo sapiens
114
RAB11A
8766
Affinity Capture-MS
Homo sapiens
115
C14orf169
Affinity Capture-MS
Homo sapiens
116
YIPF2
78992
Affinity Capture-MS
Homo sapiens
117
SNW1
22938
Affinity Capture-MS
Homo sapiens
Two-hybrid
Homo sapiens
118
ADRM1
11047
Co-fractionation
Homo sapiens
119
SYN1
Two-hybrid
Homo sapiens
120
ST13
6767
Co-fractionation
Homo sapiens
121
SNRPA1
6627
Cross-Linking-MS (XL-MS)
Homo sapiens
122
PTCH1
Affinity Capture-MS
Homo sapiens
123
RSPRY1
89970
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
124
KRT77
374454
Cross-Linking-MS (XL-MS)
Homo sapiens
125
APLP1
333
Two-hybrid
Homo sapiens
126
EXOSC7
23016
Two-hybrid
Homo sapiens
127
ABLIM1
3983
Two-hybrid
Homo sapiens
128
SPRTN
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
129
KRT6B
3854
Cross-Linking-MS (XL-MS)
Homo sapiens
130
RBM22
55696
Two-hybrid
Homo sapiens
131
USP13
Affinity Capture-Western
Homo sapiens
132
TXLNB
Two-hybrid
Homo sapiens
133
SH3GL1
6455
Two-hybrid
Homo sapiens
134
BTF3
689
Affinity Capture-MS
Homo sapiens
135
TTR
7276
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
136
GFAP
2670
Two-hybrid
Homo sapiens
Proximity Label-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
137
MYOC
4653
Affinity Capture-MS
Homo sapiens
138
SYVN1
84447
Affinity Capture-Western
Homo sapiens
Affinity Capture-Western
Homo sapiens
139
UBE2N
7334
Affinity Capture-MS
Homo sapiens
140
SETDB1
Two-hybrid
Homo sapiens
141
SFPQ
6421
Two-hybrid
Homo sapiens
142
PSIP1
11168
Affinity Capture-MS
Homo sapiens
143
WTAP
9589
Affinity Capture-MS
Homo sapiens
144
RBM48
Two-hybrid
Homo sapiens
145
TCTEX1D2
Affinity Capture-MS
Homo sapiens
146
B3GNT2
10678
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
147
KRT3
3850
Cross-Linking-MS (XL-MS)
Homo sapiens
148
PRC1
9055
Affinity Capture-MS
Homo sapiens
149
SRRM2
23524
Affinity Capture-MS
Homo sapiens
150
MICAL1
64780
Affinity Capture-Western
Homo sapiens
151
HSPH1
10808
Co-fractionation
Homo sapiens
152
NR4A1
Affinity Capture-MS
Homo sapiens
153
APIP
51074
Two-hybrid
Homo sapiens
154
VCAM1
7412
Affinity Capture-MS
Homo sapiens
155
CUL1
8454
Affinity Capture-MS
Homo sapiens
156
GSK3B
2932
Two-hybrid
Homo sapiens
157
PRNP
5621
Affinity Capture-MS
Homo sapiens
158
VRK3
51231
Affinity Capture-MS
Homo sapiens
159
MAPK3
5595
Co-fractionation
Homo sapiens
160
HIST1H4A
8359
Affinity Capture-MS
Homo sapiens
161
CDKN1A
Two-hybrid
Homo sapiens
162
MSX2
Affinity Capture-MS
Homo sapiens
163
PSMD14
10213
Affinity Capture-MS
Homo sapiens
164
CBL
867
Affinity Capture-MS
Homo sapiens
165
RCC2
55920
Co-fractionation
Homo sapiens
166
SH3GL3
Two-hybrid
Homo sapiens
167
TRIM16
10626
Affinity Capture-Western
Homo sapiens
168
TOX4
Affinity Capture-MS
Homo sapiens
169
KRT14
3861
Cross-Linking-MS (XL-MS)
Homo sapiens
170
PKN1
5585
Two-hybrid
Homo sapiens
Biochemical Activity
Homo sapiens
Two-hybrid
Homo sapiens
171
UBTF
7343
Affinity Capture-MS
Homo sapiens
172
MAGOH
4116
Affinity Capture-MS
Homo sapiens
173
CYLD
Affinity Capture-MS
Homo sapiens
174
YEATS4
Co-fractionation
Homo sapiens
175
MRPL44
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
176
GOLGA4
Co-fractionation
Homo sapiens
177
PSMA3
5684
Affinity Capture-MS
Homo sapiens
178
XPO1
7514
Affinity Capture-MS
Homo sapiens
179
RC3H2
Affinity Capture-MS
Homo sapiens
180
TJP1
7082
Affinity Capture-MS
Homo sapiens
181
MAFG
Two-hybrid
Homo sapiens
182
HNRNPF
3185
Co-fractionation
Homo sapiens
183
CDK2
1017
Affinity Capture-MS
Homo sapiens
184
NMT1
4836
Affinity Capture-MS
Homo sapiens
185
UPP2
Affinity Capture-MS
Homo sapiens
Co-purification
Homo sapiens
186
MYC
Affinity Capture-MS
Homo sapiens
187
BAG1
573
Affinity Capture-MS
Homo sapiens
188
SARAF
Affinity Capture-MS
Homo sapiens
189
RIBC2
Two-hybrid
Homo sapiens
190
DDRGK1
65992
Affinity Capture-MS
Homo sapiens
191
UBE2U
Affinity Capture-MS
Homo sapiens
192
DSP
1832
Reconstituted Complex
Homo sapiens
Two-hybrid
Homo sapiens
193
PA2G4
5036
Affinity Capture-MS
Homo sapiens
194
KRT18
3875
Proximity Label-MS
Homo sapiens
195
RNF43
Proximity Label-MS
Homo sapiens
196
EIF3F
8665
Affinity Capture-MS
Homo sapiens
197
NEIL3
Protein-RNA
Homo sapiens
198
TSGA10
Affinity Capture-MS
Homo sapiens
Affinity Capture-Western
Homo sapiens
Affinity Capture-Western
Homo sapiens
199
TP53
7157
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
200
FOLR1
2348
Affinity Capture-MS
Homo sapiens
201
BFSP1
Reconstituted Complex
Homo sapiens
202
PURA
5813
Co-fractionation
Homo sapiens
203
RYK
6259
Affinity Capture-MS
Homo sapiens
204
SQSTM1
8878
Affinity Capture-Western
Homo sapiens
Affinity Capture-Western
Homo sapiens
205
SSBP2
Affinity Capture-MS
Homo sapiens
206
VPS33A
65082
Co-fractionation
Homo sapiens
207
ZYX
7791
Co-fractionation
Homo sapiens
208
EEF1D
1936
Affinity Capture-MS
Homo sapiens
Co-fractionation
Homo sapiens
209
BRD1
23774
Two-hybrid
Homo sapiens
210
PRKX
5613
Affinity Capture-MS
Homo sapiens
211
SMIM8
Affinity Capture-MS
Homo sapiens
212
NEFM
4741
Proximity Label-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Cross-Linking-MS (XL-MS)
Homo sapiens
Cross-Linking-MS (XL-MS)
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Cross-Linking-MS (XL-MS)
Homo sapiens
213
PRMT1
3276
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
214
CPSF6
11052
Co-fractionation
Homo sapiens
215
CYP3A43
Affinity Capture-MS
Homo sapiens
216
CDC73
Affinity Capture-MS
Homo sapiens
217
KRT17
3872
Cross-Linking-MS (XL-MS)
Homo sapiens
218
SP1
Affinity Capture-MS
Homo sapiens
219
CD4
920
Affinity Capture-MS
Homo sapiens
220
USP11
8237
Affinity Capture-MS
Homo sapiens
221
KAT7
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
222
CAPZB
832
Affinity Capture-MS
Homo sapiens
223
INA
9118
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
224
TRIM28
10155
Two-hybrid
Homo sapiens
225
MCM2
4171
Affinity Capture-MS
Homo sapiens
226
CASP3
836
Biochemical Activity
Homo sapiens
227
IQGAP1
8826
Co-fractionation
Homo sapiens
228
KRT5
3852
Cross-Linking-MS (XL-MS)
Homo sapiens
229
ITGA4
3676
Affinity Capture-MS
Homo sapiens
230
CRMP1
1400
Reconstituted Complex
Homo sapiens
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
231
RPL29
6159
Co-fractionation
Homo sapiens
232
PSMA8
143471
Co-fractionation
Homo sapiens
233
RAB8B
51762
Affinity Capture-Western
Homo sapiens
234
TFCP2
7024
Affinity Capture-MS
Homo sapiens
235
NIF3L1
60491
Two-hybrid
Homo sapiens
236
PDLIM1
9124
Two-hybrid
Homo sapiens
237
HSPBP1
23640
Affinity Capture-MS
Homo sapiens
238
UBR4
23352
Co-fractionation
Homo sapiens
239
RAD23B
5887
Affinity Capture-Western
Homo sapiens
Affinity Capture-MS
Homo sapiens
240
NRSN1
Affinity Capture-MS
Homo sapiens
241
PRPH
5630
Proximity Label-MS
Homo sapiens
Two-hybrid
Homo sapiens
242
PARK2
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
243
RPS10
6204
Co-fractionation
Homo sapiens
244
TUBGCP4
27229
Two-hybrid
Homo sapiens
245
SRRT
51593
Two-hybrid
Homo sapiens
246
CHMP4B
128866
Affinity Capture-MS
Homo sapiens
247
FUBP1
8880
Two-hybrid
Homo sapiens
248
NTRK1
4914
Affinity Capture-MS
Homo sapiens
249
TAB2
Two-hybrid
Homo sapiens
250
RPA4
Proximity Label-MS
Homo sapiens
251
ANKRD35
Two-hybrid
Homo sapiens
252
NUMB
8650
Affinity Capture-MS
Homo sapiens
253
MYL12A
10627
Co-fractionation
Homo sapiens
254
MYH9
4627
Co-fractionation
Homo sapiens
255
LARP1
23367
Co-fractionation
Homo sapiens
256
HABP4
Two-hybrid
Homo sapiens
257
OGT
8473
Reconstituted Complex
Homo sapiens
258
ACAT1
38
Affinity Capture-MS
Homo sapiens
259
ZBTB2
57621
Affinity Capture-MS
Homo sapiens
260
EFNA4
Affinity Capture-MS
Homo sapiens
261
YAE1D1
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
262
METTL14
Affinity Capture-MS
Homo sapiens
263
ZHX1
Two-hybrid
Homo sapiens
264
ECT2
1894
Affinity Capture-MS
Homo sapiens
265
FAM60A
Affinity Capture-MS
Homo sapiens
266
NOC4L
79050
Two-hybrid
Homo sapiens
267
TAF6
6878
Co-fractionation
Homo sapiens
268
SIRPA
140885
Reconstituted Complex
Homo sapiens
Affinity Capture-Western
Homo sapiens
Reconstituted Complex
Homo sapiens
269
HYPK
25764
Affinity Capture-MS
Homo sapiens
Affinity Capture-Western
Homo sapiens
270
PSMA2
5683
Co-fractionation
Homo sapiens
271
KARS
3735
Two-hybrid
Homo sapiens
272
TRIM68
55128
Affinity Capture-MS
Homo sapiens
273
ACE2
59272
Affinity Capture-MS
Homo sapiens
Affinity Capture-Western
Homo sapiens
Affinity Capture-MS
Homo sapiens
Proximity Label-MS
Homo sapiens
274
OCIAD1
54940
Proximity Label-MS
Homo sapiens
275
ASB16
92591
Affinity Capture-MS
Homo sapiens
276
Dusp14
Two-hybrid
Mus musculus
277
NEFL
4747
Two-hybrid
Homo sapiens
Cross-Linking-MS (XL-MS)
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
278
RABAC1
10567
Two-hybrid
Homo sapiens
279
RPL12
6136
Affinity Capture-MS
Homo sapiens
280
SIRT6
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
281
RNF2
Affinity Capture-MS
Homo sapiens
282
SEH1L
81929
Co-fractionation
Homo sapiens
283
PPP2R5A
5525
Co-fractionation
Homo sapiens
284
TNFRSF14
Two-hybrid
Homo sapiens
285
CLCN2
Affinity Capture-MS
Homo sapiens
286
FLOT1
10211
Affinity Capture-MS
Homo sapiens
287
DZIP3
Affinity Capture-MS
Homo sapiens
288
STYXL1
Affinity Capture-MS
Homo sapiens
289
PLEKHA4
57664
Affinity Capture-MS
Homo sapiens
290
HMGB1
3146
Co-fractionation
Homo sapiens
291
SLC25A6
293
Two-hybrid
Homo sapiens
292
MCM5
4174
Affinity Capture-MS
Homo sapiens
293
KRT10
3858
Cross-Linking-MS (XL-MS)
Homo sapiens
294
RPA1
6117
Two-hybrid
Homo sapiens
295
MEN1
4221
Affinity Capture-Western
Homo sapiens
Reconstituted Complex
Homo sapiens
296
EFNA1
Affinity Capture-MS
Homo sapiens
297
CASP8
841
Two-hybrid
Homo sapiens
298
NHLRC2
374354
Affinity Capture-MS
Homo sapiens
299
HSPB1
3315
Two-hybrid
Homo sapiens
300
UFL1
23376
Affinity Capture-MS
Homo sapiens
301
MBNL1
4154
Affinity Capture-MS
Homo sapiens
302
ACTA1
58
Affinity Capture-Western
Homo sapiens
303
LRRK2
120892
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
304
RPS7
6201
Affinity Capture-MS
Homo sapiens
305
METTL3
Affinity Capture-MS
Homo sapiens
306
SPG20
23111
Affinity Capture-MS
Homo sapiens
307
SERBP1
26135
Two-hybrid
Homo sapiens
Affinity Capture-MS
Homo sapiens
308
UHRF1
29128
Co-fractionation
Homo sapiens
309
SUMO3
6612
Two-hybrid
Homo sapiens
310
RC3H1
149041
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
311
ATXN3
4287
Affinity Capture-MS
Homo sapiens
312
VIM
7431
Two-hybrid
Homo sapiens
Co-crystal Structure
Homo sapiens
Co-crystal Structure
Homo sapiens
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
Cross-Linking-MS (XL-MS)
Homo sapiens
Two-hybrid
Homo sapiens
Co-crystal Structure
Homo sapiens
Co-crystal Structure
Homo sapiens
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
Cross-Linking-MS (XL-MS)
Homo sapiens
313
CCR1
Affinity Capture-MS
Homo sapiens
314
ASB2
Affinity Capture-MS
Homo sapiens
315
UBE2H
7328
Affinity Capture-MS
Homo sapiens
316
SLFN11
91607
Proximity Label-MS
Homo sapiens
317
OSBP2
Co-fractionation
Homo sapiens
318
XIAP
Affinity Capture-MS
Homo sapiens
Affinity Capture-Western
Homo sapiens
Co-localization
Homo sapiens
319
FBXO25
Affinity Capture-MS
Homo sapiens
320
THOC2
57187
Co-fractionation
Homo sapiens
321
PBK
Co-fractionation
Homo sapiens
322
CHFR
Affinity Capture-MS
Homo sapiens
323
BASP1
10409
Co-fractionation
Homo sapiens
324
EPPK1
83481
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
325
APP
351
Reconstituted Complex
Homo sapiens
326
TMPO
7112
Affinity Capture-MS
Homo sapiens
327
KIAA1429
25962
Affinity Capture-MS
Homo sapiens
328
RNH1
6050
Co-fractionation
Homo sapiens
329
CEMIP
57214
Affinity Capture-MS
Homo sapiens
330
KIF5B
3799
Co-fractionation
Homo sapiens
331
COPS5
10987
Affinity Capture-MS
Homo sapiens
332
SCRIB
23513
Affinity Capture-MS
Homo sapiens
333
CALM3
808
Affinity Capture-MS
Homo sapiens
334
YWHAG
7532
Affinity Capture-MS
Homo sapiens
335
EIF5B
9669
Cross-Linking-MS (XL-MS)
Homo sapiens
336
DDOST
1650
Affinity Capture-MS
Homo sapiens
337
ABCE1
6059
Affinity Capture-MS
Homo sapiens
338
NR1H2
Two-hybrid
Homo sapiens
339
RAD51
Two-hybrid
Homo sapiens
340
SERPINH1
871
Co-fractionation
Homo sapiens
341
GOPC
57120
Two-hybrid
Homo sapiens
342
KLHL20
Affinity Capture-MS
Homo sapiens
343
NME2
4831
Affinity Capture-Western
Homo sapiens
344
MYCN
Affinity Capture-MS
Homo sapiens
345
CHD3
1107
Two-hybrid
Homo sapiens
346
C18orf21
Affinity Capture-MS
Homo sapiens
347
TRIM15
PCA
Homo sapiens
348
ZNF217
7764
Affinity Capture-MS
Homo sapiens
349
KRT8
3856
Proximity Label-MS
Homo sapiens
Cross-Linking-MS (XL-MS)
Homo sapiens
350
KRT12
3859
Cross-Linking-MS (XL-MS)
Homo sapiens
351
PRPF6
24148
Two-hybrid
Homo sapiens
352
ITGB3
3690
Affinity Capture-Western
Homo sapiens
353
HNF1A
Affinity Capture-MS
Homo sapiens
354
RB1CC1
9821
Affinity Capture-MS
Homo sapiens
355
C3orf62
Affinity Capture-MS
Homo sapiens
356
SDCCAG3
Two-hybrid
Homo sapiens
357
KRT6C
286887
Cross-Linking-MS (XL-MS)
Homo sapiens
358
CERS3
Affinity Capture-MS
Homo sapiens
359
STAU1
6780
Affinity Capture-MS
Homo sapiens
360
LRIF1
Two-hybrid
Homo sapiens
361
ATF2
Affinity Capture-MS
Homo sapiens
362
CTSA
5476
Affinity Capture-MS
Homo sapiens
363
FAM107A
Two-hybrid
Homo sapiens
364
FAM118B
Two-hybrid
Homo sapiens
365
VCP
7415
Affinity Capture-MS
Homo sapiens
366
ALK
238
Affinity Capture-MS
Homo sapiens
367
SYNC
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
368
KRT75
9119
Cross-Linking-MS (XL-MS)
Homo sapiens
369
SUMO2
6613
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
370
DCTN1
1639
Affinity Capture-Western
Homo sapiens
Affinity Capture-MS
Homo sapiens
371
SSUH2
Affinity Capture-MS
Homo sapiens
372
BECN1
8678
Affinity Capture-Western
Homo sapiens
373
KRT2
3849
Cross-Linking-MS (XL-MS)
Homo sapiens
374
ARMCX2
9823
Two-hybrid
Homo sapiens
375
DKK2
Affinity Capture-MS
Homo sapiens
376
UPP1
7378
Affinity Capture-MS
Homo sapiens
Co-purification
Homo sapiens
377
BAG3
9531
Affinity Capture-MS
Homo sapiens
378
CAD
790
Co-fractionation
Homo sapiens
379
HAP1
Two-hybrid
Homo sapiens
380
ACTN1
87
Co-fractionation
Homo sapiens
381
GAN
8139
Affinity Capture-MS
Homo sapiens
Affinity Capture-Western
Homo sapiens
Affinity Capture-Western
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
382
RHBDD1
84236
Affinity Capture-MS
Homo sapiens
383
FANCD2
Affinity Capture-MS
Homo sapiens
384
CUL3
8452
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
385
ASB15
142685
Affinity Capture-MS
Homo sapiens
386
YWHAZ
7534
Affinity Capture-Western
Homo sapiens
Affinity Capture-Western
Homo sapiens
Reconstituted Complex
Homo sapiens
387
EIF4G1
1981
Co-fractionation
Homo sapiens
388
NELFCD
51497
Affinity Capture-MS
Homo sapiens
389
CCT6A
908
Co-fractionation
Homo sapiens
390
NAT10
55226
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
391
RLIM
51132
Affinity Capture-MS
Homo sapiens
392
COPS8
10920
Co-fractionation
Homo sapiens
393
CTTN
2017
Affinity Capture-MS
Homo sapiens
394
PDIA3
2923
Co-fractionation
Homo sapiens
395
XPNPEP3
63929
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
396
THOC5
8563
Co-fractionation
Homo sapiens
397
PSMD7
5713
Two-hybrid
Homo sapiens
398
NXF1
10482
Two-hybrid
Homo sapiens
399
AURKB
9212
Affinity Capture-MS
Homo sapiens
400
PRKACA
5566
Affinity Capture-MS
Homo sapiens
401
MAPK6
Affinity Capture-MS
Homo sapiens
402
FBXO6
26270
Affinity Capture-MS
Homo sapiens
403
AKT2
208
Affinity Capture-Western
Homo sapiens
Affinity Capture-Western
Homo sapiens
404
RPAP3
79657
Co-fractionation
Homo sapiens
405
PSMB5
5693
Co-fractionation
Homo sapiens
406
PLA2G2A
5320
Affinity Capture-MS
Homo sapiens
Affinity Capture-Western
Homo sapiens
Reconstituted Complex
Homo sapiens
407
CLTC
1213
Co-fractionation
Homo sapiens
408
KRT16
3868
Affinity Capture-MS
Homo sapiens
Affinity Capture-Western
Homo sapiens
Cross-Linking-MS (XL-MS)
Homo sapiens
409
BAG4
Two-hybrid
Homo sapiens
410
LY6D
8581
Affinity Capture-MS
Homo sapiens
411
ARRB2
409
Affinity Capture-MS
Homo sapiens
412
DIS3L2
129563
Two-hybrid
Homo sapiens
413
SPTAN1
6709
Affinity Capture-Western
Homo sapiens
Affinity Capture-Western
Homo sapiens
414
PSMD1
5707
Co-fractionation
Homo sapiens
415
Elavl4
Two-hybrid
Mus musculus
416
NUP133
55746
Affinity Capture-MS
Homo sapiens
417
DFNB31
Affinity Capture-MS
Homo sapiens
418
CASP7
Biochemical Activity
Homo sapiens
419
POLR1C
9533
Two-hybrid
Homo sapiens
420
LGALS3
3958
Affinity Capture-MS
Homo sapiens
421
SMURF1
57154
Affinity Capture-MS
Homo sapiens
422
HDAC1
3065
Affinity Capture-MS
Homo sapiens
423
EIF4A3
9775
Affinity Capture-MS
Homo sapiens
424
CREB1
Two-hybrid
Homo sapiens
425
ATP2A2
488
Cross-Linking-MS (XL-MS)
Homo sapiens
426
PKP1
5317
Reconstituted Complex
Homo sapiens
427
IDE
3416
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
428
TXN
7295
Two-hybrid
Homo sapiens
429
KRT20
54474
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
430
ARRB1
408
Affinity Capture-MS
Homo sapiens
431
PINK1
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
432
WDR59
79726
Two-hybrid
Homo sapiens
433
ZUFSP
221302
Affinity Capture-MS
Homo sapiens
434
C9orf72
Affinity Capture-MS
Homo sapiens
435
TRIM29
23650
Affinity Capture-MS
Homo sapiens
436
IVNS1ABP
Two-hybrid
Homo sapiens
437
KIAA0408
Two-hybrid
Homo sapiens
438
CRCT1
Two-hybrid
Homo sapiens
439
CDC5L
988
Affinity Capture-MS
Homo sapiens
View the network
image/svg+xml
Pathways in which VIM is involved