Gene description for VIM
Gene name vimentin
Gene symbol VIM
Other names/aliases CTRCT30
HEL113
Species Homo sapiens
 Database cross references - VIM
ExoCarta ExoCarta_7431
Vesiclepedia VP_7431
Entrez Gene 7431
HGNC 12692
MIM 193060
UniProt P08670  
 VIM identified in sEVs derived from the following tissue/cell type
B cells 20458337    
B cells 20458337    
B cells 20458337    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Chondrocytes 35931686    
Chondrocytes 35931686    
Chondrocytes 35931686    
Chondrocytes 35931686    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Hepatocellular carcinoma cells 26054723    
Hepatocellular carcinoma cells 26054723    
Hepatocellular carcinoma cells 26054723    
Liver cancer cells 25265333    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Mesenchymal stem cells Unpublished / Not applicable
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Nasopharyngeal carcinoma cells 25857718    
Nasopharyngeal carcinoma cells 25857718    
Nasopharyngeal carcinoma cells 25857718    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
Prostate cancer cells 25844599    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
T lymphocytes 34108659    
Thymus 23844026    
 Gene ontology annotations for VIM
Molecular Function
    double-stranded RNA binding GO:0003725 IDA
    structural constituent of cytoskeleton GO:0005200 IBA
    structural constituent of cytoskeleton GO:0005200 IDA
    structural constituent of eye lens GO:0005212 IEA
    protein binding GO:0005515 IPI
    protein domain specific binding GO:0019904 IPI
    identical protein binding GO:0042802 IPI
    molecular adaptor activity GO:0060090 EXP
    scaffold protein binding GO:0097110 IPI
    keratin filament binding GO:1990254 IPI
Biological Process
    positive regulation of gene expression GO:0010628 IEA
    negative regulation of neuron projection development GO:0010977 IEA
    astrocyte development GO:0014002 IEA
    neuron projection development GO:0031175 IEA
    positive regulation of collagen biosynthetic process GO:0032967 IMP
    regulation of mRNA stability GO:0043488 IMP
    intermediate filament organization GO:0045109 IBA
    intermediate filament organization GO:0045109 ISS
    Bergmann glial cell differentiation GO:0060020 IEA
    lens fiber cell development GO:0070307 IEA
    cellular response to lipopolysaccharide GO:0071222 IMP
    cellular response to muramyl dipeptide GO:0071225 IMP
    cellular response to type II interferon GO:0071346 IEA
Subcellular Localization
    cytoplasm GO:0005737 IBA
    cytoplasm GO:0005737 IDA
    peroxisome GO:0005777 IDA
    microtubule organizing center GO:0005815 TAS
    cytosol GO:0005829 IDA
    cytosol GO:0005829 TAS
    cytoskeleton GO:0005856 IDA
    cytoskeleton GO:0005856 TAS
    intermediate filament GO:0005882 IBA
    intermediate filament GO:0005882 IDA
    plasma membrane GO:0005886 IBA
    plasma membrane GO:0005886 ISS
    focal adhesion GO:0005925 HDA
    nuclear matrix GO:0016363 IEA
    axon GO:0030424 IBA
    cell leading edge GO:0031252 IEA
    intermediate filament cytoskeleton GO:0045111 IDA
    phagocytic vesicle GO:0045335 IEA
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified VIM in sEVs
1
Experiment ID 79
MISEV standards
Biophysical techniques
CD81|MHCII
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 1
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
2
Experiment ID 80
MISEV standards
Biophysical techniques
CD81|MHCII
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis -Sample 2
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
3
Experiment ID 81
MISEV standards
Biophysical techniques
CD81|MHCII
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 3
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
4
Experiment ID 489
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 490
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
6
Experiment ID 491
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
7
Experiment ID 492
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
8
Experiment ID 412
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX|ACTB
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
9
Experiment ID 414
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
10
Experiment ID 426
MISEV standards
Biophysical techniques
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
11
Experiment ID 427
MISEV standards
Biophysical techniques
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
12
Experiment ID 494
MISEV standards
EM
Biophysical techniques
CD9|CD81|CD151|CD63|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name Osteoarthritic cartilage
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
13
Experiment ID 496
MISEV standards
Biophysical techniques
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name Healthy cartilage
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
14
Experiment ID 497
MISEV standards
Biophysical techniques
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
15
Experiment ID 498
MISEV standards
EM
Biophysical techniques
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
16
Experiment ID 407
MISEV standards
EM
Biophysical techniques
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
17
Experiment ID 419
MISEV standards
Biophysical techniques
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
18
Experiment ID 419
MISEV standards
Biophysical techniques
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
19
Experiment ID 420
MISEV standards
Biophysical techniques
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
20
Experiment ID 420
MISEV standards
Biophysical techniques
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
21
Experiment ID 405
MISEV standards
EM
Biophysical techniques
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
22
Experiment ID 363
MISEV standards
Biophysical techniques
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
DCLK1
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
23
Experiment ID 364
MISEV standards
Biophysical techniques
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
DCLK1
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
24
Experiment ID 365
MISEV standards
Biophysical techniques
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
DCLK1
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
25
Experiment ID 234
MISEV standards
EM
Biophysical techniques
TSG101|Alix|HSC70|GAPDH
Enriched markers
HSP90B1
Negative markers
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-C3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
26
Experiment ID 235
MISEV standards
EM
Biophysical techniques
TSG101|Alix|HSC70|GAPDH
Enriched markers
HSP90B1
Negative markers
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
27
Experiment ID 236
MISEV standards
EM
Biophysical techniques
TSG101|Alix|HSC70|GAPDH
Enriched markers
HSP90B1
Negative markers
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name MHCC97L
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
28
Experiment ID 267
MISEV standards
Biophysical techniques
TSG101|Alix
Enriched markers
CANX|HSP90B1
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25265333    
Organism Homo sapiens
Experiment description Quantitative Proteomic Analysis of Exosome Protein Content Changes Induced by Hepatitis B Virus in Huh-7 Cells Using SILAC Labeling and LC-MS/MS
Authors "Zhao X, Wu Y, Duan J, Ma Y, Shen Z, Wei L, Cui X, Zhang J, Xie Y, Liu J"
Journal name J Proteome Res
Publication year 2014
Sample Liver cancer cells
Sample name Huh-7 - Transfected with HBx plasmids
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
29
Experiment ID 417
MISEV standards
EM
Biophysical techniques
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX|ACTB
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
30
Experiment ID 411
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
31
Experiment ID 254
MISEV standards
EM
Biophysical techniques
TSG101|FLOT1|CD81
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name MNT-1
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
32
Experiment ID 254
MISEV standards
EM
Biophysical techniques
TSG101|FLOT1|CD81
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name MNT-1
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
33
Experiment ID 256
MISEV standards
EM
Biophysical techniques
TSG101|FLOT1
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name 501mel
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
34
Experiment ID 257
MISEV standards
EM
Biophysical techniques
TSG101|FLOT1
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name Daju
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
35
Experiment ID 258
MISEV standards
EM
Biophysical techniques
TSG101|FLOT1|CD81
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name SKMEL28
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
36
Experiment ID 259
MISEV standards
EM
Biophysical techniques
TSG101|FLOT1
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name A375M
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
37
Experiment ID 260
MISEV standards
EM
Biophysical techniques
TSG101|FLOT1|CD81
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name 1205Lu
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
38
Experiment ID 126
MISEV standards
Biophysical techniques
GAPDH
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors "Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim"
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
39
Experiment ID 488
MISEV standards
EM
Biophysical techniques
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
40
Experiment ID 418
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
41
Experiment ID 219
MISEV standards
EM
Biophysical techniques
CD63|CD9
Enriched markers
HSP90B1
Negative markers
qNano
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25857718    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from nasopharyngeal carcinoma cell identifies intercellular transfer of angiogenic proteins
Authors "Chan YK, Zhang H, Liu P, Tsao GS, Li Lung M, Mak NK, Ngok-Shun Wong R, Ying-Kit Yue P"
Journal name Int J Cancer
Publication year 2015
Sample Nasopharyngeal carcinoma cells
Sample name C666-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.17-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
42
Experiment ID 220
MISEV standards
EM
Biophysical techniques
CD63|CD9
Enriched markers
HSP90B1
Negative markers
qNano
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25857718    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from nasopharyngeal carcinoma cell identifies intercellular transfer of angiogenic proteins
Authors "Chan YK, Zhang H, Liu P, Tsao GS, Li Lung M, Mak NK, Ngok-Shun Wong R, Ying-Kit Yue P"
Journal name Int J Cancer
Publication year 2015
Sample Nasopharyngeal carcinoma cells
Sample name NP69
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.17-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
43
Experiment ID 221
MISEV standards
EM
Biophysical techniques
CD63|CD9
Enriched markers
HSP90B1
Negative markers
qNano
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25857718    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from nasopharyngeal carcinoma cell identifies intercellular transfer of angiogenic proteins
Authors "Chan YK, Zhang H, Liu P, Tsao GS, Li Lung M, Mak NK, Ngok-Shun Wong R, Ying-Kit Yue P"
Journal name Int J Cancer
Publication year 2015
Sample Nasopharyngeal carcinoma cells
Sample name NP460
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.17-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
44
Experiment ID 413
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
45
Experiment ID 211
MISEV standards
EM
Biophysical techniques
TSG101|Alix|EpCAM|TFRC
Enriched markers
cytochrome c|GOLGA2
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
46
Experiment ID 212
MISEV standards
CEM
Biophysical techniques
TSG101|Alix|EpCAM|TFRC
Enriched markers
Cytochrome C|GOLGA2
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
47
Experiment ID 406
MISEV standards
EM
Biophysical techniques
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
48
Experiment ID 415
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
49
Experiment ID 434
MISEV standards
Biophysical techniques
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
50
Experiment ID 435
MISEV standards
Biophysical techniques
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
51
Experiment ID 408
MISEV standards
EM
Biophysical techniques
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX|ACTB
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
52
Experiment ID 409
MISEV standards
EM
Biophysical techniques
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
53
Experiment ID 416
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
54
Experiment ID 275
MISEV standards
EM
Biophysical techniques
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
AIF
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel sensitive
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.12-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry/Flow cytometry/Western blotting
55
Experiment ID 834
MISEV standards
EM
Biophysical techniques
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
56
Experiment ID 835
MISEV standards
EM
Biophysical techniques
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
57
Experiment ID 410
MISEV standards
EM
Biophysical techniques
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
58
Experiment ID 217
MISEV standards
EM
Biophysical techniques
TSG101|CD81|CD9|CD63
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for VIM
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 TGOLN2 10618
Affinity Capture-MS Homo sapiens
2 ISG15 9636
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 KRT76 51350
Cross-Linking-MS (XL-MS) Homo sapiens
4 DGCR14  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
5 KRT1 3848
Cross-Linking-MS (XL-MS) Homo sapiens
6 RIN3  
Affinity Capture-MS Homo sapiens
7 PKP2 5318
Two-hybrid Homo sapiens
8 KRT6A 3853
Cross-Linking-MS (XL-MS) Homo sapiens
9 GADD45A  
Two-hybrid Homo sapiens
10 CDH5  
Affinity Capture-Western Homo sapiens
11 GLB1 2720
Affinity Capture-MS Homo sapiens
12 KIF20A 10112
Affinity Capture-MS Homo sapiens
13 THOC7 80145
Co-fractionation Homo sapiens
14 KPNA2 3838
Co-fractionation Homo sapiens
15 SLC27A6  
Two-hybrid Homo sapiens
16 ATN1  
Two-hybrid Homo sapiens
17 RNF208  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
18 PRKDC 5591
Co-fractionation Homo sapiens
19 EFNA3  
Affinity Capture-MS Homo sapiens
20 DPPA4  
Two-hybrid Homo sapiens
21 PPL 5493
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
22 PSMC5 5705
Two-hybrid Homo sapiens
23 WDR76  
Affinity Capture-MS Homo sapiens
24 STX1A 6804
Two-hybrid Homo sapiens
25 KIF23 9493
Affinity Capture-MS Homo sapiens
26 GNS 2799
Co-fractionation Homo sapiens
27 TRIOBP 11078
Two-hybrid Homo sapiens
28 EGFL8  
Affinity Capture-MS Homo sapiens
29 PIAS4  
Two-hybrid Homo sapiens
30 CALD1 800
Affinity Capture-MS Homo sapiens
31 SLC9A9 285195
Affinity Capture-MS Homo sapiens
32 ASB9  
Affinity Capture-MS Homo sapiens
33 HMG20B  
Two-hybrid Homo sapiens
Co-fractionation Homo sapiens
34 MECP2 4204
Affinity Capture-MS Homo sapiens
35 WBP2 23558
Affinity Capture-MS Homo sapiens
36 ALS2CR11  
Two-hybrid Homo sapiens
37 RAD23A 5886
Affinity Capture-Western Homo sapiens
38 DYNLT1 6993
Affinity Capture-MS Homo sapiens
39 KIF14 9928
Affinity Capture-MS Homo sapiens
40 AKT1 207
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
41 XRCC4  
Two-hybrid Homo sapiens
42 PPM1B 5495
Affinity Capture-MS Homo sapiens
43 ANXA7 310
Two-hybrid Homo sapiens
44 UTP14A 10813
Two-hybrid Homo sapiens
45 RNF4 6047
Affinity Capture-MS Homo sapiens
46 USP14 9097
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
47 FOXK1 221937
Co-fractionation Homo sapiens
48 RRP9 9136
Co-fractionation Homo sapiens
49 PSME1 5720
Two-hybrid Homo sapiens
50 NOD2 64127
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
51 MAPRE1 22919
Affinity Capture-MS Homo sapiens
52 PNMA5 114824
Two-hybrid Homo sapiens
53 CERS2 29956
Affinity Capture-MS Homo sapiens
54 YAP1 10413
Affinity Capture-MS Homo sapiens
55 MAN2A2 4122
Two-hybrid Homo sapiens
56 SLX4  
Affinity Capture-MS Homo sapiens
57 TCHP  
Two-hybrid Homo sapiens
58 YWHAQ 10971
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
59 CAPN1 823
Affinity Capture-MS Homo sapiens
60 BRAP  
Co-fractionation Homo sapiens
61 ZYG11B  
Affinity Capture-MS Homo sapiens
62 MGMT 4255
Affinity Capture-MS Homo sapiens
63 TXN2 25828
Two-hybrid Homo sapiens
64 SCARNA22  
Affinity Capture-RNA Homo sapiens
65 ANLN 54443
Affinity Capture-MS Homo sapiens
66 HSPA5 3309
Affinity Capture-MS Homo sapiens
67 AHSA1 10598
Affinity Capture-MS Homo sapiens
68 HTRA2 27429
Protein-peptide Homo sapiens
Biochemical Activity Homo sapiens
69 KIF15 56992
Two-hybrid Homo sapiens
70 AGPAT1 10554
Affinity Capture-MS Homo sapiens
71 PLA2G4A 5321
Affinity Capture-Western Homo sapiens
72 LMNB1 4001
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
73 SH3YL1  
Two-hybrid Homo sapiens
74 PRMT8  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
75 NES 10763
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
76 ATP6AP2 10159
Affinity Capture-MS Homo sapiens
77 DES 1674
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
78 BHLHE40  
Two-hybrid Homo sapiens
79 LOR  
Two-hybrid Homo sapiens
80 FN1 2335
Affinity Capture-MS Homo sapiens
81 PPHLN1  
Two-hybrid Homo sapiens
82 KRT15 3866
Cross-Linking-MS (XL-MS) Homo sapiens
83 UBR1 197131
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
84 RPA3 6119
Proximity Label-MS Homo sapiens
85 SIK1  
Affinity Capture-MS Homo sapiens
86 AHR 196
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
87 ING5  
Two-hybrid Homo sapiens
88 GXYLT1 283464
Affinity Capture-MS Homo sapiens
89 NCF1  
Affinity Capture-MS Homo sapiens
90 KRT19 3880
Proximity Label-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
91 NFATC2  
Two-hybrid Homo sapiens
92 TNNT1  
Two-hybrid Homo sapiens
93 UROD 7389
Two-hybrid Homo sapiens
94 PSMB2 5690
Co-fractionation Homo sapiens
95 CPEB4  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
96 NUDT21 11051
Co-fractionation Homo sapiens
97 GRB2 2885
Two-hybrid Homo sapiens
98 KRT84 3890
Cross-Linking-MS (XL-MS) Homo sapiens
99 PLEC 5339
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
100 URGCP 55665
Co-fractionation Homo sapiens
101 FABP4 2167
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
102 MTA1 9112
Affinity Capture-MS Homo sapiens
103 PSMB7 5695
Co-fractionation Homo sapiens
104 THOC3  
Co-fractionation Homo sapiens
105 SEPT9 10801
Affinity Capture-MS Homo sapiens
106 CWF19L2  
Two-hybrid Homo sapiens
107 KRT72 140807
Cross-Linking-MS (XL-MS) Homo sapiens
108 HSP90AA1 3320
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
109 PUF60 22827
Two-hybrid Homo sapiens
110 PSMA1 5682
Two-hybrid Homo sapiens
Co-fractionation Homo sapiens
111 TSC22D1 8848
Two-hybrid Homo sapiens
112 KLK10 5655
Affinity Capture-MS Homo sapiens
113 AIMP2 7965
Affinity Capture-MS Homo sapiens
114 RAB11A 8766
Affinity Capture-MS Homo sapiens
115 C14orf169  
Affinity Capture-MS Homo sapiens
116 YIPF2 78992
Affinity Capture-MS Homo sapiens
117 SNW1 22938
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
118 ADRM1 11047
Co-fractionation Homo sapiens
119 SYN1  
Two-hybrid Homo sapiens
120 ST13 6767
Co-fractionation Homo sapiens
121 SNRPA1 6627
Cross-Linking-MS (XL-MS) Homo sapiens
122 PTCH1  
Affinity Capture-MS Homo sapiens
123 RSPRY1 89970
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
124 KRT77 374454
Cross-Linking-MS (XL-MS) Homo sapiens
125 APLP1 333
Two-hybrid Homo sapiens
126 EXOSC7 23016
Two-hybrid Homo sapiens
127 ABLIM1 3983
Two-hybrid Homo sapiens
128 SPRTN  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
129 KRT6B 3854
Cross-Linking-MS (XL-MS) Homo sapiens
130 RBM22 55696
Two-hybrid Homo sapiens
131 USP13  
Affinity Capture-Western Homo sapiens
132 TXLNB  
Two-hybrid Homo sapiens
133 SH3GL1 6455
Two-hybrid Homo sapiens
134 BTF3 689
Affinity Capture-MS Homo sapiens
135 TTR 7276
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
136 GFAP 2670
Two-hybrid Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
137 MYOC 4653
Affinity Capture-MS Homo sapiens
138 SYVN1 84447
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
139 UBE2N 7334
Affinity Capture-MS Homo sapiens
140 SETDB1  
Two-hybrid Homo sapiens
141 SFPQ 6421
Two-hybrid Homo sapiens
142 PSIP1 11168
Affinity Capture-MS Homo sapiens
143 WTAP 9589
Affinity Capture-MS Homo sapiens
144 RBM48  
Two-hybrid Homo sapiens
145 TCTEX1D2  
Affinity Capture-MS Homo sapiens
146 B3GNT2 10678
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
147 KRT3 3850
Cross-Linking-MS (XL-MS) Homo sapiens
148 PRC1 9055
Affinity Capture-MS Homo sapiens
149 SRRM2 23524
Affinity Capture-MS Homo sapiens
150 MICAL1 64780
Affinity Capture-Western Homo sapiens
151 HSPH1 10808
Co-fractionation Homo sapiens
152 NR4A1  
Affinity Capture-MS Homo sapiens
153 APIP 51074
Two-hybrid Homo sapiens
154 VCAM1 7412
Affinity Capture-MS Homo sapiens
155 CUL1 8454
Affinity Capture-MS Homo sapiens
156 GSK3B 2932
Two-hybrid Homo sapiens
157 PRNP 5621
Affinity Capture-MS Homo sapiens
158 VRK3 51231
Affinity Capture-MS Homo sapiens
159 MAPK3 5595
Co-fractionation Homo sapiens
160 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
161 CDKN1A  
Two-hybrid Homo sapiens
162 MSX2  
Affinity Capture-MS Homo sapiens
163 PSMD14 10213
Affinity Capture-MS Homo sapiens
164 CBL 867
Affinity Capture-MS Homo sapiens
165 RCC2 55920
Co-fractionation Homo sapiens
166 SH3GL3  
Two-hybrid Homo sapiens
167 TRIM16 10626
Affinity Capture-Western Homo sapiens
168 TOX4  
Affinity Capture-MS Homo sapiens
169 KRT14 3861
Cross-Linking-MS (XL-MS) Homo sapiens
170 PKN1 5585
Two-hybrid Homo sapiens
Biochemical Activity Homo sapiens
Two-hybrid Homo sapiens
171 UBTF 7343
Affinity Capture-MS Homo sapiens
172 MAGOH 4116
Affinity Capture-MS Homo sapiens
173 CYLD  
Affinity Capture-MS Homo sapiens
174 YEATS4  
Co-fractionation Homo sapiens
175 MRPL44  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
176 GOLGA4  
Co-fractionation Homo sapiens
177 PSMA3 5684
Affinity Capture-MS Homo sapiens
178 XPO1 7514
Affinity Capture-MS Homo sapiens
179 RC3H2  
Affinity Capture-MS Homo sapiens
180 TJP1 7082
Affinity Capture-MS Homo sapiens
181 MAFG  
Two-hybrid Homo sapiens
182 HNRNPF 3185
Co-fractionation Homo sapiens
183 CDK2 1017
Affinity Capture-MS Homo sapiens
184 NMT1 4836
Affinity Capture-MS Homo sapiens
185 UPP2  
Affinity Capture-MS Homo sapiens
Co-purification Homo sapiens
186 MYC  
Affinity Capture-MS Homo sapiens
187 BAG1 573
Affinity Capture-MS Homo sapiens
188 SARAF  
Affinity Capture-MS Homo sapiens
189 RIBC2  
Two-hybrid Homo sapiens
190 DDRGK1 65992
Affinity Capture-MS Homo sapiens
191 UBE2U  
Affinity Capture-MS Homo sapiens
192 DSP 1832
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
193 PA2G4 5036
Affinity Capture-MS Homo sapiens
194 KRT18 3875
Proximity Label-MS Homo sapiens
195 RNF43  
Proximity Label-MS Homo sapiens
196 EIF3F 8665
Affinity Capture-MS Homo sapiens
197 NEIL3  
Protein-RNA Homo sapiens
198 TSGA10  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
199 TP53 7157
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
200 FOLR1 2348
Affinity Capture-MS Homo sapiens
201 BFSP1  
Reconstituted Complex Homo sapiens
202 PURA 5813
Co-fractionation Homo sapiens
203 RYK 6259
Affinity Capture-MS Homo sapiens
204 SQSTM1 8878
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
205 SSBP2  
Affinity Capture-MS Homo sapiens
206 VPS33A 65082
Co-fractionation Homo sapiens
207 ZYX 7791
Co-fractionation Homo sapiens
208 EEF1D 1936
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
209 BRD1 23774
Two-hybrid Homo sapiens
210 PRKX 5613
Affinity Capture-MS Homo sapiens
211 SMIM8  
Affinity Capture-MS Homo sapiens
212 NEFM 4741
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
213 PRMT1 3276
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
214 CPSF6 11052
Co-fractionation Homo sapiens
215 CYP3A43  
Affinity Capture-MS Homo sapiens
216 CDC73  
Affinity Capture-MS Homo sapiens
217 KRT17 3872
Cross-Linking-MS (XL-MS) Homo sapiens
218 SP1  
Affinity Capture-MS Homo sapiens
219 CD4 920
Affinity Capture-MS Homo sapiens
220 USP11 8237
Affinity Capture-MS Homo sapiens
221 KAT7  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
222 CAPZB 832
Affinity Capture-MS Homo sapiens
223 INA 9118
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
224 TRIM28 10155
Two-hybrid Homo sapiens
225 MCM2 4171
Affinity Capture-MS Homo sapiens
226 CASP3 836
Biochemical Activity Homo sapiens
227 IQGAP1 8826
Co-fractionation Homo sapiens
228 KRT5 3852
Cross-Linking-MS (XL-MS) Homo sapiens
229 ITGA4 3676
Affinity Capture-MS Homo sapiens
230 CRMP1 1400
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
231 RPL29 6159
Co-fractionation Homo sapiens
232 PSMA8 143471
Co-fractionation Homo sapiens
233 RAB8B 51762
Affinity Capture-Western Homo sapiens
234 TFCP2 7024
Affinity Capture-MS Homo sapiens
235 NIF3L1 60491
Two-hybrid Homo sapiens
236 PDLIM1 9124
Two-hybrid Homo sapiens
237 HSPBP1 23640
Affinity Capture-MS Homo sapiens
238 UBR4 23352
Co-fractionation Homo sapiens
239 RAD23B 5887
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
240 NRSN1  
Affinity Capture-MS Homo sapiens
241 PRPH 5630
Proximity Label-MS Homo sapiens
Two-hybrid Homo sapiens
242 PARK2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
243 RPS10 6204
Co-fractionation Homo sapiens
244 TUBGCP4 27229
Two-hybrid Homo sapiens
245 SRRT 51593
Two-hybrid Homo sapiens
246 CHMP4B 128866
Affinity Capture-MS Homo sapiens
247 FUBP1 8880
Two-hybrid Homo sapiens
248 NTRK1 4914
Affinity Capture-MS Homo sapiens
249 TAB2  
Two-hybrid Homo sapiens
250 RPA4  
Proximity Label-MS Homo sapiens
251 ANKRD35  
Two-hybrid Homo sapiens
252 NUMB 8650
Affinity Capture-MS Homo sapiens
253 MYL12A 10627
Co-fractionation Homo sapiens
254 MYH9 4627
Co-fractionation Homo sapiens
255 LARP1 23367
Co-fractionation Homo sapiens
256 HABP4  
Two-hybrid Homo sapiens
257 OGT 8473
Reconstituted Complex Homo sapiens
258 ACAT1 38
Affinity Capture-MS Homo sapiens
259 ZBTB2 57621
Affinity Capture-MS Homo sapiens
260 EFNA4  
Affinity Capture-MS Homo sapiens
261 YAE1D1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
262 METTL14  
Affinity Capture-MS Homo sapiens
263 ZHX1  
Two-hybrid Homo sapiens
264 ECT2 1894
Affinity Capture-MS Homo sapiens
265 FAM60A  
Affinity Capture-MS Homo sapiens
266 NOC4L 79050
Two-hybrid Homo sapiens
267 TAF6 6878
Co-fractionation Homo sapiens
268 SIRPA 140885
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
269 HYPK 25764
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
270 PSMA2 5683
Co-fractionation Homo sapiens
271 KARS 3735
Two-hybrid Homo sapiens
272 TRIM68 55128
Affinity Capture-MS Homo sapiens
273 ACE2 59272
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
274 OCIAD1 54940
Proximity Label-MS Homo sapiens
275 ASB16 92591
Affinity Capture-MS Homo sapiens
276 Dusp14  
Two-hybrid Mus musculus
277 NEFL 4747
Two-hybrid Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
278 RABAC1 10567
Two-hybrid Homo sapiens
279 RPL12 6136
Affinity Capture-MS Homo sapiens
280 SIRT6  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
281 RNF2  
Affinity Capture-MS Homo sapiens
282 SEH1L 81929
Co-fractionation Homo sapiens
283 PPP2R5A 5525
Co-fractionation Homo sapiens
284 TNFRSF14  
Two-hybrid Homo sapiens
285 CLCN2  
Affinity Capture-MS Homo sapiens
286 FLOT1 10211
Affinity Capture-MS Homo sapiens
287 DZIP3  
Affinity Capture-MS Homo sapiens
288 STYXL1  
Affinity Capture-MS Homo sapiens
289 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
290 HMGB1 3146
Co-fractionation Homo sapiens
291 SLC25A6 293
Two-hybrid Homo sapiens
292 MCM5 4174
Affinity Capture-MS Homo sapiens
293 KRT10 3858
Cross-Linking-MS (XL-MS) Homo sapiens
294 RPA1 6117
Two-hybrid Homo sapiens
295 MEN1 4221
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
296 EFNA1  
Affinity Capture-MS Homo sapiens
297 CASP8 841
Two-hybrid Homo sapiens
298 NHLRC2 374354
Affinity Capture-MS Homo sapiens
299 HSPB1 3315
Two-hybrid Homo sapiens
300 UFL1 23376
Affinity Capture-MS Homo sapiens
301 MBNL1 4154
Affinity Capture-MS Homo sapiens
302 ACTA1 58
Affinity Capture-Western Homo sapiens
303 LRRK2 120892
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
304 RPS7 6201
Affinity Capture-MS Homo sapiens
305 METTL3  
Affinity Capture-MS Homo sapiens
306 SPG20 23111
Affinity Capture-MS Homo sapiens
307 SERBP1 26135
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
308 UHRF1 29128
Co-fractionation Homo sapiens
309 SUMO3 6612
Two-hybrid Homo sapiens
310 RC3H1 149041
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
311 ATXN3 4287
Affinity Capture-MS Homo sapiens
312 VIM 7431
Two-hybrid Homo sapiens
Co-crystal Structure Homo sapiens
Co-crystal Structure Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Two-hybrid Homo sapiens
Co-crystal Structure Homo sapiens
Co-crystal Structure Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
313 CCR1  
Affinity Capture-MS Homo sapiens
314 ASB2  
Affinity Capture-MS Homo sapiens
315 UBE2H 7328
Affinity Capture-MS Homo sapiens
316 SLFN11 91607
Proximity Label-MS Homo sapiens
317 OSBP2  
Co-fractionation Homo sapiens
318 XIAP  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
319 FBXO25  
Affinity Capture-MS Homo sapiens
320 THOC2 57187
Co-fractionation Homo sapiens
321 PBK  
Co-fractionation Homo sapiens
322 CHFR  
Affinity Capture-MS Homo sapiens
323 BASP1 10409
Co-fractionation Homo sapiens
324 EPPK1 83481
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
325 APP 351
Reconstituted Complex Homo sapiens
326 TMPO 7112
Affinity Capture-MS Homo sapiens
327 KIAA1429 25962
Affinity Capture-MS Homo sapiens
328 RNH1 6050
Co-fractionation Homo sapiens
329 CEMIP 57214
Affinity Capture-MS Homo sapiens
330 KIF5B 3799
Co-fractionation Homo sapiens
331 COPS5 10987
Affinity Capture-MS Homo sapiens
332 SCRIB 23513
Affinity Capture-MS Homo sapiens
333 CALM3 808
Affinity Capture-MS Homo sapiens
334 YWHAG 7532
Affinity Capture-MS Homo sapiens
335 EIF5B 9669
Cross-Linking-MS (XL-MS) Homo sapiens
336 DDOST 1650
Affinity Capture-MS Homo sapiens
337 ABCE1 6059
Affinity Capture-MS Homo sapiens
338 NR1H2  
Two-hybrid Homo sapiens
339 RAD51  
Two-hybrid Homo sapiens
340 SERPINH1 871
Co-fractionation Homo sapiens
341 GOPC 57120
Two-hybrid Homo sapiens
342 KLHL20  
Affinity Capture-MS Homo sapiens
343 NME2 4831
Affinity Capture-Western Homo sapiens
344 MYCN  
Affinity Capture-MS Homo sapiens
345 CHD3 1107
Two-hybrid Homo sapiens
346 C18orf21  
Affinity Capture-MS Homo sapiens
347 TRIM15  
PCA Homo sapiens
348 ZNF217 7764
Affinity Capture-MS Homo sapiens
349 KRT8 3856
Proximity Label-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
350 KRT12 3859
Cross-Linking-MS (XL-MS) Homo sapiens
351 PRPF6 24148
Two-hybrid Homo sapiens
352 ITGB3 3690
Affinity Capture-Western Homo sapiens
353 HNF1A  
Affinity Capture-MS Homo sapiens
354 RB1CC1 9821
Affinity Capture-MS Homo sapiens
355 C3orf62  
Affinity Capture-MS Homo sapiens
356 SDCCAG3  
Two-hybrid Homo sapiens
357 KRT6C 286887
Cross-Linking-MS (XL-MS) Homo sapiens
358 CERS3  
Affinity Capture-MS Homo sapiens
359 STAU1 6780
Affinity Capture-MS Homo sapiens
360 LRIF1  
Two-hybrid Homo sapiens
361 ATF2  
Affinity Capture-MS Homo sapiens
362 CTSA 5476
Affinity Capture-MS Homo sapiens
363 FAM107A  
Two-hybrid Homo sapiens
364 FAM118B  
Two-hybrid Homo sapiens
365 VCP 7415
Affinity Capture-MS Homo sapiens
366 ALK 238
Affinity Capture-MS Homo sapiens
367 SYNC  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
368 KRT75 9119
Cross-Linking-MS (XL-MS) Homo sapiens
369 SUMO2 6613
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
370 DCTN1 1639
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
371 SSUH2  
Affinity Capture-MS Homo sapiens
372 BECN1 8678
Affinity Capture-Western Homo sapiens
373 KRT2 3849
Cross-Linking-MS (XL-MS) Homo sapiens
374 ARMCX2 9823
Two-hybrid Homo sapiens
375 DKK2  
Affinity Capture-MS Homo sapiens
376 UPP1 7378
Affinity Capture-MS Homo sapiens
Co-purification Homo sapiens
377 BAG3 9531
Affinity Capture-MS Homo sapiens
378 CAD 790
Co-fractionation Homo sapiens
379 HAP1  
Two-hybrid Homo sapiens
380 ACTN1 87
Co-fractionation Homo sapiens
381 GAN 8139
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
382 RHBDD1 84236
Affinity Capture-MS Homo sapiens
383 FANCD2  
Affinity Capture-MS Homo sapiens
384 CUL3 8452
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
385 ASB15 142685
Affinity Capture-MS Homo sapiens
386 YWHAZ 7534
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
387 EIF4G1 1981
Co-fractionation Homo sapiens
388 NELFCD 51497
Affinity Capture-MS Homo sapiens
389 CCT6A 908
Co-fractionation Homo sapiens
390 NAT10 55226
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
391 RLIM 51132
Affinity Capture-MS Homo sapiens
392 COPS8 10920
Co-fractionation Homo sapiens
393 CTTN 2017
Affinity Capture-MS Homo sapiens
394 PDIA3 2923
Co-fractionation Homo sapiens
395 XPNPEP3 63929
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
396 THOC5 8563
Co-fractionation Homo sapiens
397 PSMD7 5713
Two-hybrid Homo sapiens
398 NXF1 10482
Two-hybrid Homo sapiens
399 AURKB 9212
Affinity Capture-MS Homo sapiens
400 PRKACA 5566
Affinity Capture-MS Homo sapiens
401 MAPK6  
Affinity Capture-MS Homo sapiens
402 FBXO6 26270
Affinity Capture-MS Homo sapiens
403 AKT2 208
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
404 RPAP3 79657
Co-fractionation Homo sapiens
405 PSMB5 5693
Co-fractionation Homo sapiens
406 PLA2G2A 5320
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
407 CLTC 1213
Co-fractionation Homo sapiens
408 KRT16 3868
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
409 BAG4  
Two-hybrid Homo sapiens
410 LY6D 8581
Affinity Capture-MS Homo sapiens
411 ARRB2 409
Affinity Capture-MS Homo sapiens
412 DIS3L2 129563
Two-hybrid Homo sapiens
413 SPTAN1 6709
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
414 PSMD1 5707
Co-fractionation Homo sapiens
415 Elavl4  
Two-hybrid Mus musculus
416 NUP133 55746
Affinity Capture-MS Homo sapiens
417 DFNB31  
Affinity Capture-MS Homo sapiens
418 CASP7  
Biochemical Activity Homo sapiens
419 POLR1C 9533
Two-hybrid Homo sapiens
420 LGALS3 3958
Affinity Capture-MS Homo sapiens
421 SMURF1 57154
Affinity Capture-MS Homo sapiens
422 HDAC1 3065
Affinity Capture-MS Homo sapiens
423 EIF4A3 9775
Affinity Capture-MS Homo sapiens
424 CREB1  
Two-hybrid Homo sapiens
425 ATP2A2 488
Cross-Linking-MS (XL-MS) Homo sapiens
426 PKP1 5317
Reconstituted Complex Homo sapiens
427 IDE 3416
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
428 TXN 7295
Two-hybrid Homo sapiens
429 KRT20 54474
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
430 ARRB1 408
Affinity Capture-MS Homo sapiens
431 PINK1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
432 WDR59 79726
Two-hybrid Homo sapiens
433 ZUFSP 221302
Affinity Capture-MS Homo sapiens
434 C9orf72  
Affinity Capture-MS Homo sapiens
435 TRIM29 23650
Affinity Capture-MS Homo sapiens
436 IVNS1ABP  
Two-hybrid Homo sapiens
437 KIAA0408  
Two-hybrid Homo sapiens
438 CRCT1  
Two-hybrid Homo sapiens
439 CDC5L 988
Affinity Capture-MS Homo sapiens
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here