Gene description for CPSF6
Gene name cleavage and polyadenylation specific factor 6, 68kDa
Gene symbol CPSF6
Other names/aliases CFIM
CFIM68
HPBRII-4
HPBRII-7
Species Homo sapiens
 Database cross references - CPSF6
ExoCarta ExoCarta_11052
Vesiclepedia VP_11052
Entrez Gene 11052
HGNC 13871
MIM 604979
UniProt Q16630  
 CPSF6 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Hepatocellular carcinoma cells 26054723    
Hepatocytes 26054723    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Monocytic leukemia cells 34108659    
Normal mammary epithelial cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
Prostate cancer cells 25844599    
Squamous carcinoma cells 20124223    
T lymphocytes 34108659    
 Gene ontology annotations for CPSF6
Molecular Function
    RNA binding GO:0003723 HDA
    RNA binding GO:0003723 IDA
    mRNA binding GO:0003729 IBA
    mRNA binding GO:0003729 IDA
    protein binding GO:0005515 IPI
    ribosomal large subunit binding GO:0043023 IDA
    exon-exon junction complex binding GO:1990448 IDA
Biological Process
    mRNA processing GO:0006397 IDA
    mRNA 3'-end processing GO:0031124 IDA
    positive regulation of RNA export from nucleus GO:0046833 IMP
    protein tetramerization GO:0051262 IDA
    protein heterotetramerization GO:0051290 IDA
    mRNA alternative polyadenylation GO:0110104 IBA
    mRNA alternative polyadenylation GO:0110104 IMP
    co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway GO:0180010 IDA
Subcellular Localization
    nucleus GO:0005634 IDA
    nucleoplasm GO:0005654 IDA
    nucleoplasm GO:0005654 TAS
    perichromatin fibrils GO:0005726 IDA
    cytoplasm GO:0005737 IDA
    mRNA cleavage and polyadenylation specificity factor complex GO:0005847 IBA
    mRNA cleavage and polyadenylation specificity factor complex GO:0005847 IDA
    mRNA cleavage factor complex GO:0005849 IDA
    mRNA cleavage factor complex GO:0005849 IPI
    membrane GO:0016020 HDA
    nuclear speck GO:0016607 IDA
    interchromatin granule GO:0035061 IDA
    paraspeckles GO:0042382 IDA
    ribonucleoprotein complex GO:1990904 IDA
 Experiment description of studies that identified CPSF6 in sEVs
1
Experiment ID 489
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 407
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
10
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
11
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
13
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
14
Experiment ID 405
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
15
Experiment ID 236
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name MHCC97L
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
16
Experiment ID 237
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
17
Experiment ID 417
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
18
Experiment ID 411
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
19
Experiment ID 418
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
20
Experiment ID 413
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
21
Experiment ID 406
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
22
Experiment ID 415
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
23
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
24
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
25
Experiment ID 408
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
26
Experiment ID 409
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
27
Experiment ID 416
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
28
Experiment ID 274
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel resistant
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.18 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Flow cytometry
Western blotting
29
Experiment ID 191
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK."
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
30
Experiment ID 410
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
 Protein-protein interactions for CPSF6
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 HDAC4  
Affinity Capture-MS Homo sapiens
2 PCF11 51585
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
3 SRPK2 6733
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
4 CSNK1A1 1452
Co-fractionation Homo sapiens
5 DDX17 10521
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
6 ACTC1 70
Proximity Label-MS Homo sapiens
7 MAP4 4134
Co-fractionation Homo sapiens
8 CSNK2A1 1457
Biochemical Activity Homo sapiens
9 SCAF4 57466
Affinity Capture-MS Homo sapiens
10 PRPF40A 55660
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
11 PARK7 11315
Affinity Capture-MS Homo sapiens
12 PQBP1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
13 ARMC7  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
14 APEX1 328
Affinity Capture-RNA Homo sapiens
15 DDX23 9416
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
16 WDR76  
Affinity Capture-MS Homo sapiens
17 CRNKL1 51340
Affinity Capture-MS Homo sapiens
18 STRN 6801
Co-fractionation Homo sapiens
19 USP39 10713
Affinity Capture-MS Homo sapiens
20 RSRP1  
Affinity Capture-MS Homo sapiens
21 CPSF7 79869
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
22 MTMR2 8898
Affinity Capture-MS Homo sapiens
23 GSPT1 2935
Co-fractionation Homo sapiens
24 SNRPD3 6634
Affinity Capture-MS Homo sapiens
25 POLR2C 5432
Affinity Capture-MS Homo sapiens
26 MECP2 4204
Affinity Capture-MS Homo sapiens
27 ARIH2 10425
Affinity Capture-MS Homo sapiens
28 RBMX 27316
Affinity Capture-MS Homo sapiens
29 CHMP4C 92421
Affinity Capture-MS Homo sapiens
30 TOLLIP 54472
Two-hybrid Homo sapiens
31 WBP4  
Reconstituted Complex Homo sapiens
32 MEPCE 56257
Affinity Capture-MS Homo sapiens
33 SUPT5H 6829
Affinity Capture-MS Homo sapiens
34 CSTF2 1478
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
35 RBM4B  
Affinity Capture-MS Homo sapiens
36 PPIH 10465
Affinity Capture-MS Homo sapiens
37 DDX20 11218
Affinity Capture-MS Homo sapiens
38 PABPC1 26986
Co-fractionation Homo sapiens
39 YAP1 10413
Affinity Capture-MS Homo sapiens
40 TTN 7273
Co-fractionation Homo sapiens
41 OGT 8473
Reconstituted Complex Homo sapiens
42 DTX2 113878
Proximity Label-MS Homo sapiens
43 P4HB 5034
Affinity Capture-MS Homo sapiens
44 SON 6651
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
45 DDX39B 7919
Affinity Capture-MS Homo sapiens
46 SND1 27044
Affinity Capture-MS Homo sapiens
47 SRPK1 6732
Affinity Capture-MS Homo sapiens
48 CCNT1  
Affinity Capture-MS Homo sapiens
49 C11orf31  
Affinity Capture-MS Homo sapiens
50 CCDC12  
Affinity Capture-MS Homo sapiens
51 ZNF326 284695
Affinity Capture-MS Homo sapiens
52 BCLAF1 9774
Affinity Capture-MS Homo sapiens
53 PHLPP1  
Proximity Label-MS Homo sapiens
54 CSTF1 1477
Affinity Capture-MS Homo sapiens
55 CUL3 8452
Affinity Capture-MS Homo sapiens
56 THOC7 80145
Affinity Capture-MS Homo sapiens
57 POLR2D  
Affinity Capture-MS Homo sapiens
58 ZC3H11A  
Affinity Capture-MS Homo sapiens
59 SLTM 79811
Affinity Capture-MS Homo sapiens
60 FN1 2335
Affinity Capture-MS Homo sapiens
61 TXNDC9 10190
Co-fractionation Homo sapiens
62 PPHLN1  
Affinity Capture-MS Homo sapiens
63 GEMIN4 50628
Affinity Capture-MS Homo sapiens
64 MFAP1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
65 RPA3 6119
Proximity Label-MS Homo sapiens
66 PHF5A 84844
Affinity Capture-MS Homo sapiens
67 P3H3 10536
Affinity Capture-MS Homo sapiens
68 NDUFA3  
Affinity Capture-MS Homo sapiens
69 HAT1 8520
Co-fractionation Homo sapiens
70 AKAP8  
Affinity Capture-MS Homo sapiens
71 NUDT21 11051
Two-hybrid Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
72 CTR9 9646
Affinity Capture-MS Homo sapiens
73 BCAS2 10286
Affinity Capture-MS Homo sapiens
74 DAB2 1601
Affinity Capture-MS Homo sapiens
75 CHTOP  
Affinity Capture-MS Homo sapiens
76 RBM25 58517
Affinity Capture-MS Homo sapiens
77 WWOX 51741
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
78 TCERG1 10915
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
79 SRSF9 8683
Affinity Capture-MS Homo sapiens
80 PUF60 22827
Co-fractionation Homo sapiens
81 TRA2B 6434
Affinity Capture-MS Homo sapiens
82 CPSF2 53981
Affinity Capture-MS Homo sapiens
83 SUGP2  
Affinity Capture-MS Homo sapiens
84 OAT 4942
Affinity Capture-MS Homo sapiens
85 ERCC3  
Co-fractionation Homo sapiens
86 WWP2 11060
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
87 LARP7 51574
Affinity Capture-MS Homo sapiens
88 GAPDH 2597
Affinity Capture-MS Homo sapiens
89 ALYREF 10189
Affinity Capture-MS Homo sapiens
90 PSMA5 5686
Co-fractionation Homo sapiens
91 SUPT6H 6830
Affinity Capture-MS Homo sapiens
92 SNRNP70 6625
Affinity Capture-MS Homo sapiens
93 PRPF4 9128
Affinity Capture-MS Homo sapiens
94 CUL7 9820
Affinity Capture-MS Homo sapiens
95 CWC22 57703
Affinity Capture-MS Homo sapiens
96 HNRNPL 3191
Affinity Capture-MS Homo sapiens
97 PTCH1  
Affinity Capture-MS Homo sapiens
98 SNRPB2 6629
Affinity Capture-MS Homo sapiens
99 CCAR1 55749
Affinity Capture-MS Homo sapiens
100 NCBP1 4686
Affinity Capture-MS Homo sapiens
101 BCKDK 10295
Affinity Capture-MS Homo sapiens
102 RBM22 55696
Affinity Capture-MS Homo sapiens
103 KCTD10 83892
Affinity Capture-MS Homo sapiens
104 PPIL4  
Affinity Capture-MS Homo sapiens
105 RPA2 6118
Proximity Label-MS Homo sapiens
106 GNS 2799
Co-fractionation Homo sapiens
107 ARL6IP4  
Affinity Capture-MS Homo sapiens
108 ZFR 51663
Affinity Capture-MS Homo sapiens
109 CAND1 55832
Affinity Capture-MS Homo sapiens
110 SNRPF 6636
Affinity Capture-MS Homo sapiens
111 SAFB 6294
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
112 VPS26A 9559
Affinity Capture-MS Homo sapiens
113 WTAP 9589
Affinity Capture-MS Homo sapiens
114 RNPS1 10921
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
115 B3GNT2 10678
Affinity Capture-MS Homo sapiens
116 CPSF4  
Affinity Capture-MS Homo sapiens
117 PAPOLG  
Affinity Capture-MS Homo sapiens
118 MRPS23 51649
Affinity Capture-MS Homo sapiens
119 NPM1 4869
Affinity Capture-RNA Homo sapiens
120 SRRM2 23524
Affinity Capture-MS Homo sapiens
121 KHDRBS1 10657
Affinity Capture-MS Homo sapiens
122 OBSL1 23363
Affinity Capture-MS Homo sapiens
123 RBM42  
Affinity Capture-MS Homo sapiens
124 P3H4 10609
Affinity Capture-MS Homo sapiens
125 LSM2 57819
Affinity Capture-MS Homo sapiens
126 UFL1 23376
Affinity Capture-MS Homo sapiens
127 JMJD6 23210
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
128 SYMPK 8189
Affinity Capture-MS Homo sapiens
129 HNRNPA0 10949
Affinity Capture-MS Homo sapiens
130 PRPF8 10594
Affinity Capture-MS Homo sapiens
131 USP10 9100
Affinity Capture-MS Homo sapiens
132 PLSCR1 5359
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
133 TRA2A 29896
Affinity Capture-MS Homo sapiens
134 UBAP2L 9898
Co-fractionation Homo sapiens
135 ACIN1 22985
Affinity Capture-MS Homo sapiens
136 SNRNP200 23020
Affinity Capture-MS Homo sapiens
137 IWS1  
Affinity Capture-MS Homo sapiens
138 SNRPD1 6632
Affinity Capture-MS Homo sapiens
139 CSTF3 1479
Affinity Capture-MS Homo sapiens
140 RAD18  
Affinity Capture-MS Homo sapiens
141 TOX4  
Affinity Capture-MS Homo sapiens
142 LUC7L2 51631
Affinity Capture-MS Homo sapiens
143 SCAF11  
Affinity Capture-MS Homo sapiens
144 MAGOH 4116
Affinity Capture-MS Homo sapiens
145 TXNL4A 10907
Affinity Capture-MS Homo sapiens
146 KDF1  
Affinity Capture-MS Homo sapiens
147 ZCCHC8 55596
Affinity Capture-MS Homo sapiens
148 HNRNPD 3184
Affinity Capture-MS Homo sapiens
149 KHSRP 8570
Co-fractionation Homo sapiens
150 LEO1 123169
Affinity Capture-MS Homo sapiens
151 XPO1 7514
Affinity Capture-MS Homo sapiens
152 RC3H2  
Affinity Capture-MS Homo sapiens
153 POLR2E 5434
Affinity Capture-MS Homo sapiens
154 WDR33 55339
Affinity Capture-MS Homo sapiens
155 NUP88 4927
Co-fractionation Homo sapiens
156 SETD2  
Affinity Capture-MS Homo sapiens
157 YLPM1 56252
Affinity Capture-MS Homo sapiens
158 TNPO3 23534
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
159 HSD17B10 3028
Affinity Capture-MS Homo sapiens
160 FUS 2521
Affinity Capture-MS Homo sapiens
161 G6PD 2539
Affinity Capture-MS Homo sapiens
162 EFTUD2 9343
Affinity Capture-MS Homo sapiens
163 MYC  
Affinity Capture-MS Homo sapiens
164 NFRKB  
Affinity Capture-MS Homo sapiens
165 THOC1 9984
Affinity Capture-MS Homo sapiens
166 TP53RK 112858
Affinity Capture-MS Homo sapiens
167 SNW1 22938
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
168 DDRGK1 65992
Affinity Capture-MS Homo sapiens
169 ADAR 103
Affinity Capture-MS Homo sapiens
170 NKAP 79576
Affinity Capture-MS Homo sapiens
171 PA2G4 5036
Affinity Capture-MS Homo sapiens
172 PSMB10 5699
Affinity Capture-MS Homo sapiens
173 TERF2  
Affinity Capture-MS Homo sapiens
174 TOE1 114034
Affinity Capture-MS Homo sapiens
175 PARP1 142
Proximity Label-MS Homo sapiens
176 MAX  
Co-fractionation Homo sapiens
177 FOLR1 2348
Affinity Capture-MS Homo sapiens
178 FXR1 8087
Affinity Capture-Western Homo sapiens
179 PHF3  
Affinity Capture-MS Homo sapiens
180 PTBP1 5725
Co-fractionation Homo sapiens
181 HNRNPK 3190
Affinity Capture-MS Homo sapiens
182 DDX39A 10212
Affinity Capture-MS Homo sapiens
183 COQ2  
Affinity Capture-MS Homo sapiens
184 ANXA5 308
Affinity Capture-MS Homo sapiens
185 DDX42 11325
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
186 KRAS 3845
Negative Genetic Homo sapiens
187 KLHL12  
Two-hybrid Homo sapiens
188 PRMT1 3276
Affinity Capture-MS Homo sapiens
189 CPSF3 51692
Affinity Capture-MS Homo sapiens
190 MRPS9 64965
Affinity Capture-MS Homo sapiens
191 ZNF830  
Affinity Capture-MS Homo sapiens
192 MYL12B 103910
Affinity Capture-MS Homo sapiens
193 RALY 22913
Affinity Capture-MS Homo sapiens
194 FAM208A  
Affinity Capture-MS Homo sapiens
195 HNRNPC 3183
Affinity Capture-MS Homo sapiens
196 CRTAP 10491
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
197 SCYL1 57410
Affinity Capture-MS Homo sapiens
198 MME 4311
Affinity Capture-MS Homo sapiens
199 HNRNPR 10236
Affinity Capture-MS Homo sapiens
200 APBB1  
Reconstituted Complex Homo sapiens
201 PPP1R10  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
202 HNRNPUL2 221092
Affinity Capture-MS Homo sapiens
203 ZNF638 27332
Affinity Capture-MS Homo sapiens
204 MDC1  
Affinity Capture-MS Homo sapiens
205 EWSR1 2130
Two-hybrid Homo sapiens
206 SF3A2 8175
Affinity Capture-MS Homo sapiens
207 C17orf85  
Affinity Capture-MS Homo sapiens
208 ZBTB8B  
Co-fractionation Homo sapiens
209 UBQLN4 56893
Two-hybrid Homo sapiens
210 UBAC1 10422
Two-hybrid Homo sapiens
211 RBM8A 9939
Affinity Capture-MS Homo sapiens
212 FOXP1 27086
Protein-RNA Homo sapiens
213 POLR2K  
Affinity Capture-MS Homo sapiens
214 NF2 4771
Affinity Capture-MS Homo sapiens
215 CLK2 1196
Affinity Capture-MS Homo sapiens
216 DLD 1738
Affinity Capture-MS Homo sapiens
217 P4HA1 5033
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
218 PARK2  
Affinity Capture-MS Homo sapiens
219 PPIL1 51645
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
220 RPS10 6204
Co-fractionation Homo sapiens
221 TCEA2  
Co-fractionation Homo sapiens
222 SMEK1 55671
Co-fractionation Homo sapiens
223 GIN1  
Two-hybrid Homo sapiens
224 SRRT 51593
Affinity Capture-MS Homo sapiens
225 SAFB2 9667
Affinity Capture-MS Homo sapiens
226 BARD1 580
Affinity Capture-MS Homo sapiens
227 NTRK1 4914
Affinity Capture-MS Homo sapiens
228 U2AF2 11338
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
229 NSRP1  
Affinity Capture-MS Homo sapiens
230 TPRKB 51002
Affinity Capture-MS Homo sapiens
231 DHX9 1660
Affinity Capture-MS Homo sapiens
232 NKTR  
Affinity Capture-MS Homo sapiens
233 HNRNPA3 220988
Affinity Capture-MS Homo sapiens
234 RBM10  
Affinity Capture-MS Homo sapiens
235 POLR2B 5431
Affinity Capture-MS Homo sapiens
236 HNRNPDL 9987
Affinity Capture-MS Homo sapiens
237 RBBP6 5930
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
238 SF3B2 10992
Affinity Capture-MS Homo sapiens
239 CDC73  
Affinity Capture-MS Homo sapiens
240 CSTF2T  
Affinity Capture-MS Homo sapiens
241 RPRD2  
Affinity Capture-MS Homo sapiens
242 METTL16 79066
Affinity Capture-MS Homo sapiens
243 DCAF13 25879
Affinity Capture-MS Homo sapiens
244 ZC3H4 23211
Affinity Capture-MS Homo sapiens
245 SYNCRIP 10492
Affinity Capture-MS Homo sapiens
246 YY1 7528
Affinity Capture-MS Homo sapiens
247 HNRNPA1 3178
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
248 HNRNPUL1 11100
Affinity Capture-MS Homo sapiens
249 POLR2A 5430
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
250 NCBP2 22916
Affinity Capture-MS Homo sapiens
251 PRPF19 27339
Affinity Capture-MS Homo sapiens
252 PSPC1 55269
Affinity Capture-MS Homo sapiens
253 FXR2 9513
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
254 PPWD1 23398
Affinity Capture-MS Homo sapiens
255 ZC3H18  
Affinity Capture-MS Homo sapiens
256 CAAP1  
Affinity Capture-MS Homo sapiens
257 P3H2  
Affinity Capture-MS Homo sapiens
258 TP63  
Affinity Capture-MS Homo sapiens
259 TOP1 7150
Affinity Capture-MS Homo sapiens
260 NHP2L1 4809
Affinity Capture-MS Homo sapiens
261 SKIV2L2 23517
Affinity Capture-MS Homo sapiens
262 DIDO1  
Affinity Capture-MS Homo sapiens
263 CHUK 1147
Affinity Capture-MS Homo sapiens
264 DDX50 79009
Affinity Capture-MS Homo sapiens
265 SMN1 6606
Affinity Capture-MS Homo sapiens
266 CDC40  
Affinity Capture-MS Homo sapiens
267 DDX3X 1654
Co-fractionation Homo sapiens
268 MEN1 4221
Affinity Capture-MS Homo sapiens
269 HNRNPM 4670
Affinity Capture-MS Homo sapiens
270 LENG8  
Affinity Capture-MS Homo sapiens
271 THRAP3 9967
Affinity Capture-MS Homo sapiens
272 PLOD1 5351
Affinity Capture-MS Homo sapiens
273 CREBBP  
Affinity Capture-Western Homo sapiens
274 RBM15 64783
Affinity Capture-MS Homo sapiens
275 THOC6 79228
Affinity Capture-MS Homo sapiens
276 NCK2 8440
Two-hybrid Homo sapiens
277 TRAP1 10131
Affinity Capture-MS Homo sapiens
278 DHX40  
Proximity Label-MS Homo sapiens
279 TRIM37  
Proximity Label-MS Homo sapiens
280 API5 8539
Affinity Capture-MS Homo sapiens
281 AKAP17A  
Affinity Capture-MS Homo sapiens
282 METTL3  
Affinity Capture-MS Homo sapiens
283 RPRD1B 58490
Affinity Capture-MS Homo sapiens
284 AR 367
Proximity Label-MS Homo sapiens
285 RC3H1 149041
Affinity Capture-MS Homo sapiens
286 VIM 7431
Co-fractionation Homo sapiens
287 ZNF318 24149
Affinity Capture-MS Homo sapiens
288 EP300 2033
Affinity Capture-MS Homo sapiens
289 UBE2H 7328
Affinity Capture-MS Homo sapiens
290 RIT1 6016
Negative Genetic Homo sapiens
291 ZMYND19  
Two-hybrid Homo sapiens
292 IGF2BP1 10642
Affinity Capture-MS Homo sapiens
293 TBC1D2 55357
Co-fractionation Homo sapiens
294 WWP1 11059
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
295 SMURF1 57154
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
296 PPIE 10450
Affinity Capture-MS Homo sapiens
297 P4HA2 8974
Affinity Capture-MS Homo sapiens
298 ZC3H14  
Affinity Capture-MS Homo sapiens
299 DHX8 1659
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
300 LSM4 25804
Affinity Capture-MS Homo sapiens
301 FAM168A  
Affinity Capture-MS Homo sapiens
302 PRPF3  
Affinity Capture-MS Homo sapiens
303 KIF5B 3799
Co-fractionation Homo sapiens
304 BUD13  
Affinity Capture-MS Homo sapiens
305 AQR 9716
Affinity Capture-MS Homo sapiens
306 SYF2  
Affinity Capture-MS Homo sapiens
307 SNRPD2 6633
Affinity Capture-MS Homo sapiens
308 ILF2 3608
Affinity Capture-MS Homo sapiens
309 PPP1CC 5501
Affinity Capture-MS Homo sapiens
310 KIAA1429 25962
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
311 RNH1 6050
Co-fractionation Homo sapiens
312 ATXN2L 11273
Affinity Capture-MS Homo sapiens
313 ISY1 57461
Affinity Capture-MS Homo sapiens
314 POLR2I 5438
Co-fractionation Homo sapiens
315 MAGOHB 55110
Affinity Capture-MS Homo sapiens
316 YES1 7525
Two-hybrid Homo sapiens
317 C8orf82  
Proximity Label-MS Homo sapiens
318 NCOA5  
Affinity Capture-MS Homo sapiens
319 SNRPC 6631
Affinity Capture-MS Homo sapiens
320 OTUB2  
Two-hybrid Homo sapiens
321 ATP5O 539
Affinity Capture-MS Homo sapiens
322 GOPC 57120
Affinity Capture-MS Homo sapiens
323 EED  
Affinity Capture-MS Homo sapiens
324 P3H1 64175
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
325 METTL14  
Affinity Capture-MS Homo sapiens
326 MYCN  
Affinity Capture-MS Homo sapiens
327 SMARCB1 6598
Co-fractionation Homo sapiens
328 FEM1A  
Affinity Capture-MS Homo sapiens
329 NEDD4 4734
Reconstituted Complex Homo sapiens
330 GEMIN5 25929
Affinity Capture-MS Homo sapiens
331 PPP1CA 5499
Affinity Capture-MS Homo sapiens
332 USP21  
Two-hybrid Homo sapiens
333 NONO 4841
Co-fractionation Homo sapiens
334 SRSF6 6431
Affinity Capture-MS Homo sapiens
335 PPP1R8 5511
Affinity Capture-MS Homo sapiens
336 DDX5 1655
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
337 LRPAP1 4043
Affinity Capture-MS Homo sapiens
338 PABPN1 8106
Affinity Capture-MS Homo sapiens
339 ZFC3H1 196441
Affinity Capture-MS Homo sapiens
340 SARNP 84324
Affinity Capture-MS Homo sapiens
341 ITCH 83737
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
342 PRPF31 26121
Affinity Capture-MS Homo sapiens
343 CEBPA  
Proximity Label-MS Homo sapiens
Protein-peptide Homo sapiens
344 SMARCC2 6601
Co-fractionation Homo sapiens
345 BAG3 9531
Affinity Capture-MS Homo sapiens
346 WDR82 80335
Affinity Capture-MS Homo sapiens
347 UBE2N 7334
Affinity Capture-MS Homo sapiens
348 SFPQ 6421
Co-fractionation Homo sapiens
349 CPSF1 29894
Affinity Capture-MS Homo sapiens
350 IPO5 3843
Co-fractionation Homo sapiens
351 PRPF4B 8899
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
352 PNN 5411
Affinity Capture-MS Homo sapiens
353 SNRPB 6628
Affinity Capture-MS Homo sapiens
354 PLRG1 5356
Affinity Capture-MS Homo sapiens
355 SRSF1 6426
Affinity Capture-MS Homo sapiens
356 HCFC1 3054
Affinity Capture-MS Homo sapiens
357 XAB2 56949
Affinity Capture-MS Homo sapiens
358 CTTN 2017
Affinity Capture-MS Homo sapiens
359 THOC5 8563
Affinity Capture-MS Homo sapiens
360 SUZ12  
Affinity Capture-MS Homo sapiens
361 SART1 9092
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
362 PRKCI 5584
Co-fractionation Homo sapiens
363 RBM26 64062
Affinity Capture-MS Homo sapiens
364 FIP1L1 81608
Affinity Capture-MS Homo sapiens
365 SRSF10 10772
Affinity Capture-MS Homo sapiens
366 CCDC8  
Affinity Capture-MS Homo sapiens
367 GLUD1 2746
Affinity Capture-MS Homo sapiens
368 TAF15 8148
Affinity Capture-MS Homo sapiens
369 PAPOLA 10914
Affinity Capture-Western Homo sapiens
370 SRRM1 10250
Affinity Capture-MS Homo sapiens
371 MRPS2 51116
Affinity Capture-MS Homo sapiens
372 SSU72 29101
Affinity Capture-MS Homo sapiens
373 ERH 2079
Affinity Capture-MS Homo sapiens
374 WBP11  
Co-fractionation Homo sapiens
375 PPIG 9360
Affinity Capture-MS Homo sapiens
376 SMARCC1 6599
Co-fractionation Homo sapiens
377 YTHDC1  
Affinity Capture-MS Homo sapiens
378 NUFIP2 57532
Affinity Capture-MS Homo sapiens
379 SAP18 10284
Affinity Capture-MS Homo sapiens
380 HNRNPA2B1 3181
Affinity Capture-MS Homo sapiens
381 YWHAB 7529
Co-fractionation Homo sapiens
382 ELAVL1 1994
Affinity Capture-MS Homo sapiens
383 EIF4A3 9775
Affinity Capture-MS Homo sapiens
384 NUP35 129401
Proximity Label-MS Homo sapiens
385 CWC15  
Affinity Capture-MS Homo sapiens
386 SNRNP40 9410
Affinity Capture-MS Homo sapiens
387 NUP107 57122
Co-fractionation Homo sapiens
388 ITSN2 50618
Two-hybrid Homo sapiens
389 DHX16 8449
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
390 EZH2  
Affinity Capture-MS Homo sapiens
391 TRIP4 9325
Affinity Capture-MS Homo sapiens
392 TRIM31  
Affinity Capture-MS Homo sapiens
393 ZCCHC10  
Affinity Capture-MS Homo sapiens
394 PRPF6 24148
Affinity Capture-MS Homo sapiens
395 LSM6 11157
Affinity Capture-MS Homo sapiens
396 EIF5A 1984
Affinity Capture-MS Homo sapiens
397 HNRNPU 3192
Affinity Capture-MS Homo sapiens
398 PAF1 54623
Affinity Capture-MS Homo sapiens
399 CLP1  
Affinity Capture-Western Homo sapiens
400 CDC5L 988
Affinity Capture-MS Homo sapiens
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here