Gene description for RBMX
Gene name RNA binding motif protein, X-linked
Gene symbol RBMX
Other names/aliases HNRNPG
HNRPG
RBMXP1
RBMXRT
RNMX
hnRNP-G
Species Homo sapiens
 Database cross references - RBMX
ExoCarta ExoCarta_27316
Vesiclepedia VP_27316
Entrez Gene 27316
HGNC 9910
MIM 300199
UniProt P38159  
 RBMX identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Cholangiocarcinoma cells 31054213    
Cholangiocarcinoma cells 31054213    
Chondrocytes 35931686    
Chondrocytes 35931686    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Endothelial cells 26027894    
Foreskin fibroblasts 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
T lymphocytes 34108659    
 Gene ontology annotations for RBMX
Molecular Function
    RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000978 IDA
    chromatin binding GO:0003682 IDA
    RNA binding GO:0003723 HDA
    RNA binding GO:0003723 IBA
    RNA binding GO:0003723 IDA
    RNA binding GO:0003723 NAS
    mRNA binding GO:0003729 IDA
    protein binding GO:0005515 IPI
    protein domain specific binding GO:0019904 IPI
    identical protein binding GO:0042802 IDA
    identical protein binding GO:0042802 IPI
Biological Process
    regulation of alternative mRNA splicing, via spliceosome GO:0000381 IDA
    mRNA splicing, via spliceosome GO:0000398 IC
    osteoblast differentiation GO:0001649 HDA
    transcription by RNA polymerase II GO:0006366 IDA
    membrane protein ectodomain proteolysis GO:0006509 IDA
    positive regulation of transcription by RNA polymerase II GO:0045944 IDA
    negative regulation of mRNA splicing, via spliceosome GO:0048025 ISS
    positive regulation of mRNA splicing, via spliceosome GO:0048026 IBA
    positive regulation of mRNA splicing, via spliceosome GO:0048026 ISS
    protein homooligomerization GO:0051260 ISS
    cellular response to interleukin-1 GO:0071347 IDA
Subcellular Localization
    euchromatin GO:0000791 IDA
    extracellular space GO:0005615 HDA
    nucleus GO:0005634 IDA
    nucleoplasm GO:0005654 TAS
    spliceosomal complex GO:0005681 IBA
    membrane GO:0016020 HDA
    protein-containing complex GO:0032991 IDA
    supraspliceosomal complex GO:0044530 IDA
    extracellular exosome GO:0070062 IDA
    catalytic step 2 spliceosome GO:0071013 IDA
    ribonucleoprotein complex GO:1990904 NAS
 Experiment description of studies that identified RBMX in sEVs
1
Experiment ID 489
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 1225
MISEV standards
✔ Biophysical techniques
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 31054213    
Organism Homo sapiens
Experiment description Phosphoproteome Profiling of Isogenic Cancer Cell-Derived Exosome Reveals HSP90 as a Potential Marker for Human Cholangiocarcinoma
Authors "Weeraphan C, Phongdara A, Chaiyawat P, Diskul-Na-Ayudthaya P, Chokchaichamnankit D, Verathamjamras C, Netsirisawan P, Yingchutrakul Y, Roytrakul S, Champattanachai V, Svasti J, Srisomsap C."
Journal name Proteomics
Publication year 2019
Sample Cholangiocarcinoma cells
Sample name KKU-M213 - in-solution digestion
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
Sucrose density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
10
Experiment ID 1226
MISEV standards
✔ Biophysical techniques
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 31054213    
Organism Homo sapiens
Experiment description Phosphoproteome Profiling of Isogenic Cancer Cell-Derived Exosome Reveals HSP90 as a Potential Marker for Human Cholangiocarcinoma
Authors "Weeraphan C, Phongdara A, Chaiyawat P, Diskul-Na-Ayudthaya P, Chokchaichamnankit D, Verathamjamras C, Netsirisawan P, Yingchutrakul Y, Roytrakul S, Champattanachai V, Svasti J, Srisomsap C."
Journal name Proteomics
Publication year 2019
Sample Cholangiocarcinoma cells
Sample name KKU-M213D5 - in-solution digestion
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
Sucrose density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
11
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
12
Experiment ID 498
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
13
Experiment ID 407
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
14
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
15
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
16
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
17
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
18
Experiment ID 226
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule mRNA
Identification method Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
PubMed ID 26027894    
Organism Homo sapiens
Experiment description "Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting"
Authors "Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar"
Journal name Journal of Extracellular Vesicles
Publication year 2015
Sample Endothelial cells
Sample name HMEC-1
Isolation/purification methods Differential ultracentrifugation
Sucrose density gradient
Flotation density 1.10 g/mL
Molecules identified in the study miRNA
Protein
snoRNA
lncRNA
yRNA
snRNA
mRNA
ncRNA
mtRNA
vtRNA
scaRNA
lincRNA
Methods used in the study Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
Western blotting
19
Experiment ID 405
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
20
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
21
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
22
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
23
Experiment ID 417
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
24
Experiment ID 411
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
25
Experiment ID 488
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
26
Experiment ID 418
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
27
Experiment ID 413
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
28
Experiment ID 211
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
29
Experiment ID 212
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
30
Experiment ID 406
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
31
Experiment ID 415
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
32
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
33
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
34
Experiment ID 408
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
35
Experiment ID 409
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
36
Experiment ID 416
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
37
Experiment ID 410
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
 Protein-protein interactions for RBMX
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 PPP1CB 5500
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
2 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
3 CSNK1A1 1452
Co-fractionation Homo sapiens
4 DDX17 10521
Affinity Capture-MS Homo sapiens
5 KIF20A 10112
Affinity Capture-MS Homo sapiens
6 CSNK2A1 1457
Biochemical Activity Homo sapiens
7 GCN1L1 10985
Co-fractionation Homo sapiens
8 PRKDC 5591
Co-fractionation Homo sapiens
9 GFM2 84340
Proximity Label-MS Homo sapiens
10 DDX23 9416
Proximity Label-MS Homo sapiens
11 IGF2BP3 10643
Affinity Capture-MS Homo sapiens
12 SNRNP70 6625
Affinity Capture-MS Homo sapiens
13 DTX3  
Affinity Capture-MS Homo sapiens
14 KIF23 9493
Affinity Capture-MS Homo sapiens
15 SF3B1 23451
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
16 AI837181  
Affinity Capture-MS Mus musculus
17 CPSF7 79869
Co-fractionation Homo sapiens
18 VPS13D 55187
Cross-Linking-MS (XL-MS) Homo sapiens
19 PTCD1 26024
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
20 PPM1A 5494
Co-fractionation Homo sapiens
21 SNRPD3 6634
Co-fractionation Homo sapiens
22 UCHL5 51377
Co-fractionation Homo sapiens
23 SFN 2810
Co-fractionation Homo sapiens
24 MECP2 4204
Affinity Capture-MS Homo sapiens
25 SREK1 140890
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
26 EEF1A1 1915
Co-fractionation Homo sapiens
27 RBM14 10432
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
28 NEIL3  
Protein-RNA Homo sapiens
29 KIF14 9928
Affinity Capture-MS Homo sapiens
30 EMC9  
Affinity Capture-MS Homo sapiens
31 RBMX 27316
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
32 CHMP4C 92421
Affinity Capture-MS Homo sapiens
33 PIP4K2C 79837
Co-fractionation Homo sapiens
34 MEPCE 56257
Affinity Capture-MS Homo sapiens
35 ROBO3  
Two-hybrid Homo sapiens
36 PSME1 5720
Co-fractionation Homo sapiens
37 SRSF3 6428
Two-hybrid Homo sapiens
Co-fractionation Homo sapiens
38 RBM7  
Two-hybrid Homo sapiens
39 TUFM 7284
Proximity Label-MS Homo sapiens
40 PPIH 10465
Co-fractionation Homo sapiens
41 GID8 54994
Affinity Capture-MS Homo sapiens
42 FOXL2  
Affinity Capture-MS Homo sapiens
43 OGT 8473
Reconstituted Complex Homo sapiens
44 RPL31 6160
Co-fractionation Homo sapiens
45 DTX2 113878
Proximity Label-MS Homo sapiens
46 HECTD1 25831
Affinity Capture-MS Homo sapiens
47 SRPK3  
Affinity Capture-MS Homo sapiens
48 SCARNA22  
Affinity Capture-RNA Homo sapiens
49 ANLN 54443
Affinity Capture-MS Homo sapiens
50 RBM39 9584
Affinity Capture-MS Homo sapiens
51 MRPS12  
Proximity Label-MS Homo sapiens
52 SIRT7  
Affinity Capture-MS Homo sapiens
53 SRSF4 6429
Affinity Capture-Western Homo sapiens
54 CUL3 8452
Affinity Capture-MS Homo sapiens
55 FN1 2335
Affinity Capture-MS Homo sapiens
56 YTHDC1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
57 C12orf65  
Proximity Label-MS Homo sapiens
58 SF3B6 51639
Co-fractionation Homo sapiens
59 HSPA4 3308
Co-fractionation Homo sapiens
60 SORBS3 10174
Two-hybrid Homo sapiens
61 PAIP1 10605
Affinity Capture-MS Homo sapiens
62 YBX1 4904
Co-fractionation Homo sapiens
63 NUDT21 11051
Co-fractionation Homo sapiens
64 Tubg1 103733
Affinity Capture-MS Mus musculus
65 RBM45  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
66 WWOX 51741
Affinity Capture-MS Homo sapiens
67 APOBEC3D  
Affinity Capture-MS Homo sapiens
68 SRSF9 8683
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
69 LRPPRC 10128
Proximity Label-MS Homo sapiens
70 TRA2B 6434
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
71 DYNC1H1 1778
Co-fractionation Homo sapiens
72 ERCC6  
Affinity Capture-MS Homo sapiens
73 HNRNPL 3191
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
74 EIF4B 1975
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
75 SNW1 22938
Affinity Capture-MS Homo sapiens
76 COLGALT1 79709
Co-fractionation Homo sapiens
77 SNRPA1 6627
Co-fractionation Homo sapiens
78 HNRNPH1 3187
Co-fractionation Homo sapiens
79 GSTP1 2950
Affinity Capture-MS Homo sapiens
80 SNRPA 6626
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
81 MCM3 4172
Co-fractionation Homo sapiens
82 RBMXL1  
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
83 LUZP4  
Affinity Capture-MS Homo sapiens
84 PMPCA 23203
Proximity Label-MS Homo sapiens
85 KLC2 64837
Co-fractionation Homo sapiens
86 RBMY1F  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
87 TARDBP 23435
Affinity Capture-MS Homo sapiens
88 BTF3 689
Affinity Capture-MS Homo sapiens
89 QKI 9444
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
90 CHCHD1  
Proximity Label-MS Homo sapiens
91 CAND1 55832
Affinity Capture-MS Homo sapiens
92 RBMY1E  
Two-hybrid Homo sapiens
93 SRSF2 6427
Co-fractionation Homo sapiens
94 SAFB 6294
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
95 RNPS1 10921
Affinity Capture-MS Homo sapiens
96 B3GNT2 10678
Affinity Capture-MS Homo sapiens
97 RBM3 5935
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
98 OSBP 5007
Co-fractionation Homo sapiens
99 PRC1 9055
Affinity Capture-MS Homo sapiens
100 MAGOHB 55110
Two-hybrid Homo sapiens
101 SRRM2 23524
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
102 KHDRBS1 10657
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
103 OBSL1 23363
Affinity Capture-MS Homo sapiens
104 MALSU1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
105 VCAM1 7412
Affinity Capture-MS Homo sapiens
106 SOCS3 9021
Two-hybrid Homo sapiens
107 TACO1  
Proximity Label-MS Homo sapiens
108 FASTKD2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
109 USP7 7874
Co-fractionation Homo sapiens
110 PLS3 5358
Co-fractionation Homo sapiens
111 Erh  
Affinity Capture-MS Mus musculus
112 CLK3  
Two-hybrid Homo sapiens
113 YWHAB 7529
Co-fractionation Homo sapiens
114 UFL1 23376
Affinity Capture-MS Homo sapiens
115 C6orf203  
Proximity Label-MS Homo sapiens
116 HNRNPA0 10949
Two-hybrid Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
117 Tra2b 20462
Two-hybrid Mus musculus
118 DDX21 9188
Affinity Capture-MS Homo sapiens
119 KLC1 3831
Co-fractionation Homo sapiens
120 TRA2A 29896
Affinity Capture-MS Homo sapiens
121 RPS6KB1 6198
Co-fractionation Homo sapiens
122 SNRPD1 6632
Co-fractionation Homo sapiens
123 MAGOH 4116
Affinity Capture-MS Homo sapiens
124 Ksr1  
Affinity Capture-MS Mus musculus
125 CYLD  
Affinity Capture-MS Homo sapiens
126 NYX  
Two-hybrid Homo sapiens
127 HNRNPD 3184
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
128 ACLY 47
Co-fractionation Homo sapiens
129 AIFM1 9131
Co-fractionation Homo sapiens
130 DHX36 170506
Affinity Capture-MS Homo sapiens
131 RC3H2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
132 IKZF3  
Affinity Capture-MS Homo sapiens
133 MTIF3  
Proximity Label-MS Homo sapiens
134 YLPM1 56252
Affinity Capture-MS Homo sapiens
135 SLK 9748
Co-fractionation Homo sapiens
136 FUS 2521
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
137 IKZF1  
Affinity Capture-MS Homo sapiens
138 TFG 10342
Co-fractionation Homo sapiens
139 MYC  
Affinity Capture-MS Homo sapiens
140 HNRNPAB 3182
Affinity Capture-MS Homo sapiens
141 CUL7 9820
Affinity Capture-MS Homo sapiens
142 DDRGK1 65992
Affinity Capture-MS Homo sapiens
143 LMNA 4000
Proximity Label-MS Homo sapiens
144 ADAR 103
Co-fractionation Homo sapiens
145 FAM103A1  
Two-hybrid Homo sapiens
146 FAM120A 23196
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
147 KRT18 3875
Co-fractionation Homo sapiens
148 CS 1431
Proximity Label-MS Homo sapiens
149 RRM2 6241
Co-fractionation Homo sapiens
150 HNRNPH2 3188
Affinity Capture-MS Homo sapiens
151 PARP1 142
Proximity Label-MS Homo sapiens
152 ILF3 3609
Co-fractionation Homo sapiens
153 FOLR1 2348
Affinity Capture-MS Homo sapiens
154 SSRP1 6749
Affinity Capture-MS Homo sapiens
155 SF3B4 10262
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
156 ATG101  
Affinity Capture-MS Homo sapiens
157 ZNF490  
Two-hybrid Homo sapiens
158 HNRNPK 3190
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Co-fractionation Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
159 RAD50 10111
Co-fractionation Homo sapiens
160 ESR1  
Affinity Capture-MS Homo sapiens
161 FASTKD3  
Proximity Label-MS Homo sapiens
162 KHDRBS2  
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
163 Srsf1 110809
Affinity Capture-MS Mus musculus
164 DHX38 9785
Cross-Linking-MS (XL-MS) Homo sapiens
165 RPSA 3921
Co-fractionation Homo sapiens
166 MYPOP  
Two-hybrid Homo sapiens
167 PSMF1 9491
Two-hybrid Homo sapiens
168 HSPA4L 22824
Co-fractionation Homo sapiens
169 PPP2R1A 5518
Affinity Capture-MS Homo sapiens
170 Srsf3 20383
Two-hybrid Mus musculus
171 JAK2 3717
Two-hybrid Homo sapiens
172 PRMT1 3276
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
173 CPSF6 11052
Affinity Capture-MS Homo sapiens
174 LNX1  
Two-hybrid Homo sapiens
175 RALY 22913
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
176 UBE2H 7328
Affinity Capture-MS Homo sapiens
177 HNRNPC 3183
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
178 FOXC1  
Affinity Capture-MS Homo sapiens
179 PPP3CA 5530
Co-fractionation Homo sapiens
180 KHDRBS3  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
181 Fus  
Affinity Capture-MS Mus musculus
182 STAT5A 6776
Two-hybrid Homo sapiens
183 USP48  
Co-fractionation Homo sapiens
184 HNRNPR 10236
Co-fractionation Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
185 ATG13 9776
Affinity Capture-MS Homo sapiens
186 CAPZB 832
Affinity Capture-MS Homo sapiens
187 RDX 5962
Co-fractionation Homo sapiens
188 MCM2 4171
Affinity Capture-MS Homo sapiens
189 Srsf9  
Two-hybrid Mus musculus
190 LIG1 3978
Co-fractionation Homo sapiens
191 NFE2L2 4780
Two-hybrid Homo sapiens
192 YARS2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
193 HINT2 84681
Proximity Label-MS Homo sapiens
194 PPP1R7 5510
Co-fractionation Homo sapiens
195 LINC00240  
Affinity Capture-MS Homo sapiens
196 SF3A2 8175
Affinity Capture-MS Homo sapiens
197 Taf15  
Affinity Capture-MS Mus musculus
198 ITGA4 3676
Affinity Capture-MS Homo sapiens
199 ATG16L1 55054
Affinity Capture-MS Homo sapiens
200 NIF3L1 60491
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
201 MTERF3  
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
202 RBM8A 9939
Co-fractionation Homo sapiens
203 HSPA8 3312
Co-fractionation Homo sapiens
204 FOXP1 27086
Protein-RNA Homo sapiens
205 MDH2 4191
Proximity Label-MS Homo sapiens
206 FOXA1  
Affinity Capture-MS Homo sapiens
207 SRRM1 10250
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
208 PARK2  
Affinity Capture-MS Homo sapiens
209 CCDC33 80125
Two-hybrid Homo sapiens
210 XRN1 54464
Two-hybrid Homo sapiens
211 PLOD2 5352
Co-fractionation Homo sapiens
212 SAFB2 9667
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
213 CIRBP 1153
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
214 U2AF2 11338
Affinity Capture-MS Homo sapiens
215 CCDC8  
Affinity Capture-MS Homo sapiens
216 DHX9 1660
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
217 TRUB2  
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
218 ENY2 56943
Affinity Capture-MS Homo sapiens
219 MRPL11 65003
Proximity Label-MS Homo sapiens
220 HNRNPA3 220988
Affinity Capture-MS Homo sapiens
221 HDAC5 10014
Affinity Capture-MS Homo sapiens
222 ACTG1 71
Co-fractionation Homo sapiens
223 BZW1 9689
Co-fractionation Homo sapiens
224 IPO9 55705
Co-fractionation Homo sapiens
225 PCBP2 5094
Two-hybrid Homo sapiens
226 LARP1 23367
Co-fractionation Homo sapiens
227 HNRNPDL 9987
Affinity Capture-MS Homo sapiens
228 NTRK1 4914
Affinity Capture-MS Homo sapiens
229 METTL14  
Affinity Capture-MS Homo sapiens
230 TRIM33 51592
Co-fractionation Homo sapiens
231 ECT2 1894
Affinity Capture-MS Homo sapiens
232 HIST1H1E 3008
Co-fractionation Homo sapiens
233 SF1 7536
Two-hybrid Homo sapiens
234 HNRNPA1 3178
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
235 DHX30 22907
Proximity Label-MS Homo sapiens
236 HNRNPUL1 11100
Co-fractionation Homo sapiens
237 Pcbp1 23983
Two-hybrid Mus musculus
238 Khdrbs3  
Affinity Capture-Western Rattus norvegicus
239 PRR3  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
240 CUL9  
Affinity Capture-MS Homo sapiens
241 HPD 3242
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
242 PRPF19 27339
Co-fractionation Homo sapiens
243 FXR2 9513
Two-hybrid Homo sapiens
244 ZC3H18  
Co-fractionation Homo sapiens
245 P3H2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
246 TOP1 7150
Affinity Capture-MS Homo sapiens
247 MATR3 9782
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
248 RNF2  
Affinity Capture-MS Homo sapiens
249 MSN 4478
Co-fractionation Homo sapiens
250 MYO6 4646
Proximity Label-MS Homo sapiens
251 METTL15  
Proximity Label-MS Homo sapiens
252 HDGF 3068
Affinity Capture-MS Homo sapiens
253 SNRPD2 6633
Co-fractionation Homo sapiens
254 SMS 6611
Co-fractionation Homo sapiens
255 TBX3 6926
Affinity Capture-MS Homo sapiens
256 AHSA1 10598
Affinity Capture-MS Homo sapiens
257 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
258 FBXW11  
Affinity Capture-MS Homo sapiens
259 TSFM 10102
Proximity Label-MS Homo sapiens
260 SEC23IP 11196
Co-fractionation Homo sapiens
261 MCM5 4174
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
262 PDHA1 5160
Co-fractionation Homo sapiens
263 RBMXL2  
Cross-Linking-MS (XL-MS) Homo sapiens
264 HNRNPM 4670
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
265 THRAP3 9967
Affinity Capture-MS Homo sapiens
266 Shoc2  
Affinity Capture-MS Mus musculus
267 PDZD8 118987
Affinity Capture-MS Homo sapiens
268 DHX40  
Proximity Label-MS Homo sapiens
269 TRIM37  
Proximity Label-MS Homo sapiens
270 TBRG4 9238
Proximity Label-MS Homo sapiens
271 HNRNPF 3185
Co-fractionation Homo sapiens
272 FOXM1  
Affinity Capture-MS Homo sapiens
273 RAC1 5879
Affinity Capture-MS Homo sapiens
274 RC3H1 149041
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
275 NUCKS1 64710
Co-fractionation Homo sapiens
276 EP300 2033
Affinity Capture-MS Homo sapiens
277 CRBN  
Affinity Capture-MS Homo sapiens
278 RIT1 6016
Negative Genetic Homo sapiens
279 CNBP 7555
Affinity Capture-MS Homo sapiens
280 USP5 8078
Co-fractionation Homo sapiens
281 Ybx1 22608
Affinity Capture-MS Mus musculus
282 PBK  
Co-fractionation Homo sapiens
283 DHX8 1659
Proximity Label-MS Homo sapiens
284 NGRN  
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
285 PDHB 5162
Co-fractionation Homo sapiens
286 MTRF1  
Proximity Label-MS Homo sapiens
287 SF3B2 10992
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
288 ILF2 3608
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
289 PPP1CC 5501
Affinity Capture-MS Homo sapiens
290 TOP2A 7153
Co-fractionation Homo sapiens
291 Trim69  
Affinity Capture-MS Mus musculus
292 FBXW7  
Synthetic Lethality Homo sapiens
Affinity Capture-MS Homo sapiens
293 NCOA5  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
294 Hnrnpk 15387
Two-hybrid Mus musculus
295 SNRPC 6631
Affinity Capture-MS Homo sapiens
296 IFIT3 3437
Affinity Capture-MS Homo sapiens
297 MRPS26 64949
Proximity Label-MS Homo sapiens
298 USP45  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
299 EED  
Affinity Capture-MS Homo sapiens
300 MYCN  
Affinity Capture-MS Homo sapiens
301 NABP1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
302 PPP1CA 5499
Co-fractionation Homo sapiens
303 RB1CC1 9821
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
304 STAU1 6780
Affinity Capture-MS Homo sapiens
305 APOBEC3C 27350
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
306 SRSF6 6431
Affinity Capture-MS Homo sapiens
307 CNNM3 26505
Two-hybrid Homo sapiens
308 DDX5 1655
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
309 TRIM11  
Affinity Capture-MS Homo sapiens
310 PRPF31 26121
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
311 CEBPA  
Protein-peptide Homo sapiens
312 FOXS1  
Affinity Capture-MS Homo sapiens
313 ST13 6767
Co-fractionation Homo sapiens
314 ELAVL2 1993
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
315 SFPQ 6421
Co-fractionation Homo sapiens
316 Grb2 14784
Two-hybrid Mus musculus
317 TAF15 8148
Affinity Capture-MS Homo sapiens
318 MRRF  
Proximity Label-MS Homo sapiens
319 FANCD2  
Affinity Capture-MS Homo sapiens
320 UPF1 5976
Co-fractionation Homo sapiens
321 RBMY1A1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
322 SNRPB 6628
Affinity Capture-MS Homo sapiens
323 PLRG1 5356
Co-fractionation Homo sapiens
324 SRSF1 6426
Co-fractionation Homo sapiens
325 CEBPG  
Co-fractionation Homo sapiens
326 RABGAP1 23637
Co-fractionation Homo sapiens
327 NXF1 10482
Two-hybrid Homo sapiens
Co-fractionation Homo sapiens
328 SF3A1 10291
Co-fractionation Homo sapiens
329 AURKB 9212
Affinity Capture-MS Homo sapiens
330 IL7R  
Protein-RNA Homo sapiens
331 FBXO6 26270
Affinity Capture-MS Homo sapiens
332 SRSF10 10772
Affinity Capture-MS Homo sapiens
333 SF3B3 23450
Co-fractionation Homo sapiens
334 CLTC 1213
Co-fractionation Homo sapiens
335 Cirbp  
Two-hybrid Mus musculus
336 MGEA5 10724
Co-fractionation Homo sapiens
337 C10orf2 56652
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
338 RBMY1J  
Two-hybrid Homo sapiens
339 Cbx1  
Affinity Capture-MS Mus musculus
340 DHX15 1665
Co-fractionation Homo sapiens
341 MCAT 27349
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
342 ATOH1  
Affinity Capture-MS Homo sapiens
343 IVNS1ABP  
Affinity Capture-MS Homo sapiens
344 ZNF746  
Affinity Capture-MS Homo sapiens
345 HNRNPA2B1 3181
Affinity Capture-MS Homo sapiens
346 ELAVL1 1994
Affinity Capture-MS Homo sapiens
347 EIF4A3 9775
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
348 EPB41L2 2037
Co-fractionation Homo sapiens
349 CWC15  
Co-fractionation Homo sapiens
350 RPS28 6234
Co-fractionation Homo sapiens
351 ITSN2 50618
Two-hybrid Homo sapiens
352 PCDHB14  
Two-hybrid Homo sapiens
353 TRIM31  
Affinity Capture-MS Homo sapiens
354 PINK1  
Affinity Capture-MS Homo sapiens
355 GRSF1 2926
Proximity Label-MS Homo sapiens
356 C9orf72  
Affinity Capture-MS Homo sapiens
357 METTL17  
Proximity Label-MS Homo sapiens
358 WARS 7453
Co-fractionation Homo sapiens
359 CDC5L 988
Affinity Capture-MS Homo sapiens
Co-purification Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
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Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here