Gene description for P3H1
Gene name prolyl 3-hydroxylase 1
Gene symbol P3H1
Other names/aliases GROS1
LEPRE1
OI8
Species Homo sapiens
 Database cross references - P3H1
ExoCarta ExoCarta_64175
Vesiclepedia VP_64175
Entrez Gene 64175
HGNC 19316
MIM 610339
UniProt Q32P28  
 P3H1 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Chondrocytes 35931686    
Chondrocytes 35931686    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Mesenchymal stem cells Unpublished / Not applicable
Mesenchymal stem cells 36408942    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
Urine 19056867    
 Gene ontology annotations for P3H1
Molecular Function
    iron ion binding GO:0005506 IEA
    protein binding GO:0005515 IPI
    protein binding GO:0005515 ISS
    collagen binding GO:0005518 ISS
    procollagen-proline 3-dioxygenase activity GO:0019797 IBA
    procollagen-proline 3-dioxygenase activity GO:0019797 ISS
    L-ascorbic acid binding GO:0031418 IEA
Biological Process
    protein folding GO:0006457 IMP
    negative regulation of cell population proliferation GO:0008285 NAS
    positive regulation of neuron projection development GO:0010976 ISS
    protein hydroxylation GO:0018126 IMP
    collagen metabolic process GO:0032963 IBA
    collagen metabolic process GO:0032963 ISS
    regulation of protein secretion GO:0050708 IMP
    protein stabilization GO:0050821 IMP
    bone development GO:0060348 IMP
    chaperone-mediated protein folding GO:0061077 ISS
    negative regulation of post-translational protein modification GO:1901874 IMP
Subcellular Localization
    nucleus GO:0005634 IDA
    cytoplasm GO:0005737 IDA
    endoplasmic reticulum GO:0005783 IBA
    endoplasmic reticulum GO:0005783 IDA
    endoplasmic reticulum lumen GO:0005788 TAS
    membrane GO:0016020 HDA
    protein-containing complex GO:0032991 ISS
    collagen-containing extracellular matrix GO:0062023 HDA
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified P3H1 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
6
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
7
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
8
Experiment ID 498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
9
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
10
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
11
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
12
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
13
Experiment ID 126
MISEV standards
✘ Biophysical techniques
✔
GAPDH
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors "Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim"
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
14
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
15
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
16
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
17
Experiment ID 834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
18
Experiment ID 835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
19
Experiment ID 63
MISEV standards
✘ Biophysical techniques
✔
AQP2
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors "Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for P3H1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 RENBP 5973
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
2 Mtx1  
Affinity Capture-MS Mus musculus
3 ACTR2 10097
Co-fractionation Homo sapiens
4 PPP3CA 5530
Co-fractionation Homo sapiens
5 HS3ST1  
Affinity Capture-MS Homo sapiens
6 ZNHIT1  
Affinity Capture-MS Homo sapiens
7 CRTAP 10491
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
8 RIN3  
Affinity Capture-MS Homo sapiens
9 ZPR1 8882
Co-fractionation Homo sapiens
10 C14orf142  
Co-fractionation Homo sapiens
11 DDX17 10521
Co-fractionation Homo sapiens
12 EMID1  
Affinity Capture-MS Homo sapiens
13 FCHO1  
Affinity Capture-MS Homo sapiens
14 UBE3A 7337
Co-fractionation Homo sapiens
15 VHL  
Affinity Capture-MS Homo sapiens
16 IKZF4  
Affinity Capture-MS Homo sapiens
17 LRRC59 55379
Proximity Label-MS Homo sapiens
18 HOOK2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
19 SNRPF 6636
Affinity Capture-MS Homo sapiens
20 Sf3a1 67465
Affinity Capture-MS Mus musculus
21 ZNF446  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
22 VPS26A 9559
Affinity Capture-MS Homo sapiens
23 ZNF397  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
24 MBIP  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
25 WDR48 57599
Affinity Capture-MS Homo sapiens
26 RNPS1 10921
Affinity Capture-MS Homo sapiens
27 BDNF 627
Affinity Capture-MS Homo sapiens
28 COL8A1 1295
Affinity Capture-MS Homo sapiens
29 POU5F1  
Affinity Capture-MS Homo sapiens
30 LPP 4026
Co-fractionation Homo sapiens
31 TOM1L1 10040
Co-fractionation Homo sapiens
32 LRSAM1 90678
Co-fractionation Homo sapiens
33 NMU  
Affinity Capture-MS Homo sapiens
34 PDIA6 10130
Co-fractionation Homo sapiens
35 MAN1A1 4121
Affinity Capture-MS Homo sapiens
36 TOR3A 64222
Affinity Capture-MS Homo sapiens
37 GPN1  
Co-fractionation Homo sapiens
38 Sod1 20655
Affinity Capture-MS Mus musculus
39 MYCN  
Affinity Capture-MS Homo sapiens
40 C1QTNF9B  
Affinity Capture-MS Homo sapiens
41 HK1 3098
Co-fractionation Homo sapiens
42 FKBP10 60681
Co-fractionation Homo sapiens
43 FAM20C 56975
Affinity Capture-MS Homo sapiens
44 LSM1 27257
Co-fractionation Homo sapiens
45 RBM8A 9939
Affinity Capture-MS Homo sapiens
46 KIF14 9928
Affinity Capture-MS Homo sapiens
47 FAM163A  
Affinity Capture-MS Homo sapiens
48 GEMIN2 8487
Affinity Capture-MS Homo sapiens
49 C1orf106  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
50 HSPBP1 23640
Co-fractionation Homo sapiens
51 CALR3  
Proximity Label-MS Homo sapiens
52 SRP9 6726
Co-fractionation Homo sapiens
53 DPP8 54878
Co-fractionation Homo sapiens
54 HRG 3273
Affinity Capture-MS Homo sapiens
55 DBNL 28988
Co-fractionation Homo sapiens
56 ERO1L 30001
Co-fractionation Homo sapiens
57 IKBIP 121457
Affinity Capture-MS Homo sapiens
58 AGFG1 3267
Co-fractionation Homo sapiens
59 SRP14 6727
Co-fractionation Homo sapiens
60 PARK2  
Affinity Capture-MS Homo sapiens
61 KRBA1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
62 XPO5 57510
Co-fractionation Homo sapiens
63 CHPF2 54480
Affinity Capture-MS Homo sapiens
64 NTRK1 4914
Affinity Capture-MS Homo sapiens
65 COL8A2 1296
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
66 COLQ  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
67 MIA3 375056
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
68 SNRPN 6638
Affinity Capture-MS Homo sapiens
69 P4HB 5034
Co-fractionation Homo sapiens
70 TPRKB 51002
Co-fractionation Homo sapiens
71 DNAJC30  
Proximity Label-MS Homo sapiens
72 P3H4 10609
Affinity Capture-MS Homo sapiens
73 SZRD1 26099
Co-fractionation Homo sapiens
74 SEC61B 10952
Proximity Label-MS Homo sapiens
75 DNAJB11 51726
Proximity Label-MS Homo sapiens
76 ALX3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
77 OGT 8473
Co-fractionation Homo sapiens
78 ADAD2  
Affinity Capture-MS Homo sapiens
79 MBTPS1 8720
Affinity Capture-MS Homo sapiens
80 ALAD 210
Co-fractionation Homo sapiens
81 HSPA5 3309
Proximity Label-MS Homo sapiens
82 CSTF2T  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
83 SLC2A4  
Affinity Capture-MS Homo sapiens
84 SMARCD1 6602
Affinity Capture-MS Homo sapiens
85 Sart3  
Affinity Capture-MS Mus musculus
86 CCDC120  
Affinity Capture-MS Homo sapiens
87 Smad3  
Affinity Capture-MS Mus musculus
88 NUDT21 11051
Affinity Capture-MS Homo sapiens
89 PRG2  
Affinity Capture-MS Homo sapiens
90 CUL3 8452
Affinity Capture-MS Homo sapiens
91 EGFR 1956
Affinity Capture-MS Homo sapiens
92 OSGEP 55644
Co-fractionation Homo sapiens
93 NAGLU 4669
Affinity Capture-MS Homo sapiens
94 FBXO6 26270
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
95 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
96 ARAF 369
Affinity Capture-MS Homo sapiens
97 TRIM68 55128
Affinity Capture-MS Homo sapiens
98 MYC  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
99 VPS37D 155382
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
100 SEC16A 9919
Affinity Capture-MS Homo sapiens
101 SBNO1 55206
Co-fractionation Homo sapiens
102 KCNN4 3783
Affinity Capture-MS Homo sapiens
103 COL10A1  
Affinity Capture-MS Homo sapiens
104 DNAJC10 54431
Proximity Label-MS Homo sapiens
105 DNAJC3 5611
Proximity Label-MS Homo sapiens
106 PTPN23 25930
Affinity Capture-MS Homo sapiens
107 P3H3 10536
Affinity Capture-MS Homo sapiens
108 UQCC2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
109 PUS1 80324
Co-fractionation Homo sapiens
110 BMP4 652
Affinity Capture-MS Homo sapiens
111 DNAJC6  
Affinity Capture-MS Homo sapiens
112 PPME1 51400
Co-fractionation Homo sapiens
113 H2AFX 3014
Affinity Capture-MS Homo sapiens
114 SNCA 6622
Affinity Capture-MS Homo sapiens
115 KIF21B 23046
Affinity Capture-MS Homo sapiens
116 WDR4 10785
Co-fractionation Homo sapiens
117 CEP170P1  
Affinity Capture-MS Homo sapiens
118 SETSIP 646817
Co-fractionation Homo sapiens
119 NPW  
Affinity Capture-MS Homo sapiens
120 CPSF6 11052
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
121 TP53 7157
Affinity Capture-MS Homo sapiens
122 UQCC1 55245
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
123 WWOX 51741
Affinity Capture-MS Homo sapiens
124 PDIA4 9601
Proximity Label-MS Homo sapiens
125 KDELC1 79070
Affinity Capture-MS Homo sapiens
126 CALU 813
Proximity Label-MS Homo sapiens
127 SF3B4 10262
Affinity Capture-MS Homo sapiens
128 AJUBA  
Affinity Capture-MS Homo sapiens
129 PFDN1 5201
Co-fractionation Homo sapiens
130 CDK18 5129
Affinity Capture-MS Homo sapiens
131 SURF2  
Co-fractionation Homo sapiens
132 METRN 79006
Affinity Capture-MS Homo sapiens
133 SFTPA2  
Affinity Capture-MS Homo sapiens
134 MAT2B 27430
Co-fractionation Homo sapiens
135 NCR3  
Affinity Capture-MS Homo sapiens
136 TIGD5  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
137 SEMA3B 7869
Affinity Capture-MS Homo sapiens
138 Srsf1 110809
Affinity Capture-MS Mus musculus
139 EDA  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
140 PPP1R12A 4659
Co-fractionation Homo sapiens
141 SH3GLB1 51100
Co-fractionation Homo sapiens
142 TSC22D4 81628
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
143 KANK2 25959
Affinity Capture-MS Homo sapiens
144 SERBP1 26135
Affinity Capture-MS Homo sapiens
145 NRD1 4898
Co-fractionation Homo sapiens
146 GAS2L1 10634
Affinity Capture-MS Homo sapiens
147 CPSF3 51692
Affinity Capture-MS Homo sapiens
148 TSN 7247
Co-fractionation Homo sapiens
149 ARIH1 25820
Co-fractionation Homo sapiens
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here