Gene description for PRKCI
Gene name protein kinase C, iota
Gene symbol PRKCI
Other names/aliases DXS1179E
PKCI
nPKC-iota
Species Homo sapiens
 Database cross references - PRKCI
ExoCarta ExoCarta_5584
Vesiclepedia VP_5584
Entrez Gene 5584
HGNC 9404
MIM 600539
UniProt P41743  
 PRKCI identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Mesenchymal stem cells 36408942    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
Urine 19056867    
 Gene ontology annotations for PRKCI
Molecular Function
    protein kinase activity GO:0004672 IDA
    protein serine/threonine kinase activity GO:0004674 IBA
    protein serine/threonine kinase activity GO:0004674 IDA
    diacylglycerol-dependent serine/threonine kinase activity GO:0004697 EXP
    diacylglycerol-dependent serine/threonine kinase activity GO:0004697 TAS
    calcium,diacylglycerol-dependent serine/threonine kinase activity GO:0004698 IEA
    diacylglycerol-dependent, calcium-independent serine/threonine kinase activity GO:0004699 ISS
    protein binding GO:0005515 IPI
    ATP binding GO:0005524 TAS
    phospholipid binding GO:0005543 IDA
    metal ion binding GO:0046872 IEA
    protein serine kinase activity GO:0106310 IEA
Biological Process
    protein phosphorylation GO:0006468 IDA
    protein targeting to membrane GO:0006612 NAS
    cytoskeleton organization GO:0007010 NAS
    actin filament organization GO:0007015 IEA
    positive regulation of neuron projection development GO:0010976 IDA
    positive regulation of neuron projection development GO:0010976 IMP
    vesicle-mediated transport GO:0016192 TAS
    cell migration GO:0016477 IEA
    establishment of cell polarity GO:0030010 IBA
    cellular response to insulin stimulus GO:0032869 IBA
    cellular response to insulin stimulus GO:0032869 ISS
    negative regulation of glial cell apoptotic process GO:0034351 IMP
    establishment of apical/basal cell polarity GO:0035089 IEA
    intracellular signal transduction GO:0035556 IBA
    eye photoreceptor cell development GO:0042462 IEA
    negative regulation of apoptotic process GO:0043066 TAS
    negative regulation of neuron apoptotic process GO:0043524 IDA
    establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 IDA
    establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 ISS
    establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 TAS
    cell-cell junction organization GO:0045216 IMP
    positive regulation of Notch signaling pathway GO:0045747 TAS
    positive regulation of D-glucose import GO:0046326 ISS
    secretion GO:0046903 NAS
    Golgi vesicle budding GO:0048194 IEA
    positive regulation of NF-kappaB transcription factor activity GO:0051092 IDA
    positive regulation of glial cell proliferation GO:0060252 IMP
    membrane organization GO:0061024 NAS
    cellular response to chemical stress GO:0062197 TAS
    response to interleukin-1 GO:0070555 IEA
    protein localization to plasma membrane GO:0072659 IBA
    regulation of postsynaptic membrane neurotransmitter receptor levels GO:0099072 IEA
    positive regulation of protein localization to plasma membrane GO:1903078 ISS
    positive regulation of endothelial cell apoptotic process GO:2000353 IMP
Subcellular Localization
    Golgi membrane GO:0000139 IEA
    nucleus GO:0005634 IDA
    nucleoplasm GO:0005654 TAS
    endosome GO:0005768 IEA
    cytosol GO:0005829 IDA
    cytosol GO:0005829 TAS
    plasma membrane GO:0005886 TAS
    brush border GO:0005903 IEA
    bicellular tight junction GO:0005923 IEA
    microtubule cytoskeleton GO:0015630 IDA
    apical plasma membrane GO:0016324 IEA
    cell leading edge GO:0031252 IEA
    Schmidt-Lanterman incisure GO:0043220 IEA
    intercellular bridge GO:0045171 IDA
    extracellular exosome GO:0070062 HDA
    tight junction GO:0070160 NAS
    Schaffer collateral - CA1 synapse GO:0098685 IEA
    glutamatergic synapse GO:0098978 IEA
    PAR polarity complex GO:0120157 IPI
    PAR polarity complex GO:0120157 ISS
 Experiment description of studies that identified PRKCI in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
6
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
7
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
9
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
10
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
11
Experiment ID 834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
13
Experiment ID 63
MISEV standards
✘ Biophysical techniques
✔
AQP2
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors "Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for PRKCI
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 KIF3B 9371
Co-fractionation Homo sapiens
2 GABARAPL1 23710
Affinity Capture-MS Homo sapiens
3 UBE2H 7328
Affinity Capture-MS Homo sapiens
4 GJD3  
Proximity Label-MS Homo sapiens
5 GABARAPL2 11345
Affinity Capture-MS Homo sapiens
6 C2CD4A  
Affinity Capture-MS Homo sapiens
7 LLGL1 3996
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
8 YWHAE 7531
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
9 TTR 7276
Two-hybrid Homo sapiens
10 PBK  
Co-fractionation Homo sapiens
11 Dido1  
Biochemical Activity Mus musculus
12 UBC 7316
Reconstituted Complex Homo sapiens
13 SSB 6741
Affinity Capture-MS Homo sapiens
14 VHL  
Biochemical Activity Homo sapiens
15 APP 351
Reconstituted Complex Homo sapiens
16 LRPPRC 10128
Co-fractionation Homo sapiens
17 MAP1LC3B 81631
Affinity Capture-MS Homo sapiens
18 IL17F  
Affinity Capture-MS Homo sapiens
19 EIF4ENIF1 56478
Affinity Capture-MS Homo sapiens
20 DDX23 9416
Co-fractionation Homo sapiens
21 CHD4 1108
Co-fractionation Homo sapiens
22 MASTL  
Affinity Capture-MS Homo sapiens
23 MARK2 2011
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
24 RASSF8 11228
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
25 KIF23 9493
Co-fractionation Homo sapiens
26 GNS 2799
Co-fractionation Homo sapiens
27 KIF5B 3799
Co-fractionation Homo sapiens
28 SPAG9 9043
Co-fractionation Homo sapiens
29 SPANXN4  
Affinity Capture-MS Homo sapiens
30 PQLC2L  
Affinity Capture-MS Homo sapiens
31 PSMD12 5718
Co-fractionation Homo sapiens
32 HSPH1 10808
Co-fractionation Homo sapiens
33 PSMB6 5694
Co-fractionation Homo sapiens
34 ST14 6768
Affinity Capture-MS Homo sapiens
35 SMC2 10592
Co-fractionation Homo sapiens
36 MCM6 4175
Co-fractionation Homo sapiens
37 PSMC2 5701
Co-fractionation Homo sapiens
38 MAGED2 10916
Affinity Capture-MS Homo sapiens
39 GSPT1 2935
Co-fractionation Homo sapiens
40 MBP 4155
Biochemical Activity Homo sapiens
41 PPM1A 5494
Co-fractionation Homo sapiens
42 NGEF  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
43 SNRPD3 6634
Co-fractionation Homo sapiens
44 RHOJ 57381
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
45 YWHAH 7533
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
46 GOLGA4  
Co-fractionation Homo sapiens
47 MARK4  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
48 SLC4A1AP  
Co-fractionation Homo sapiens
49 LRRC17 10234
Affinity Capture-MS Homo sapiens
50 KIF3A 11127
Co-fractionation Homo sapiens
51 RBM14 10432
Two-hybrid Homo sapiens
52 GPR156  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
53 HSPA8 3312
Co-fractionation Homo sapiens
54 SMC4 10051
Co-fractionation Homo sapiens
55 CASK 8573
Two-hybrid Homo sapiens
56 PXMP2  
Proximity Label-MS Homo sapiens
57 PPM1B 5495
Co-fractionation Homo sapiens
58 ADAP1  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
59 YWHAB 7529
Affinity Capture-MS Homo sapiens
60 USP21  
Affinity Capture-MS Homo sapiens
61 IL1RAP 3556
Two-hybrid Homo sapiens
62 PARK2  
Affinity Capture-MS Homo sapiens
63 KLC1 3831
Co-fractionation Homo sapiens
64 CTBP1 1487
Two-hybrid Homo sapiens
65 Frs2  
Reconstituted Complex Mus musculus
66 RAB4A 5867
Affinity Capture-Western Homo sapiens
67 ACACA 31
Co-fractionation Homo sapiens
68 DNAJC5 80331
Proximity Label-MS Homo sapiens
69 MAPT  
Biochemical Activity Homo sapiens
70 PPP2CB 5516
Co-fractionation Homo sapiens
71 FYN 2534
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
72 RPA2 6118
Two-hybrid Homo sapiens
73 MYH9 4627
Co-fractionation Homo sapiens
74 ACTN4 81
Co-fractionation Homo sapiens
75 MYO10 4651
Affinity Capture-MS Homo sapiens
76 DCAF7 10238
Affinity Capture-MS Homo sapiens
77 TSC22D1 8848
Two-hybrid Homo sapiens
78 MEOX2  
Two-hybrid Homo sapiens
79 RPL27A 6157
Affinity Capture-MS Homo sapiens
80 ARFGEF1 10565
Co-fractionation Homo sapiens
81 Fubp3  
Two-hybrid Mus musculus
82 MTMR4  
Proximity Label-MS Homo sapiens
83 NIPSNAP1 8508
Affinity Capture-MS Homo sapiens
84 ZNF609  
Affinity Capture-MS Homo sapiens
85 BZW1 9689
Co-fractionation Homo sapiens
86 ACBD3 64746
Co-fractionation Homo sapiens
87 KDF1  
Affinity Capture-MS Homo sapiens
88 PARD3 56288
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
89 ARHGAP17 55114
Affinity Capture-Western Homo sapiens
90 TJP1 7082
Co-localization Homo sapiens
91 SFPQ 6421
Affinity Capture-Western Homo sapiens
92 DUSP1  
Affinity Capture-Western Homo sapiens
93 IPO5 3843
Co-fractionation Homo sapiens
94 CDK7 1022
Biochemical Activity Homo sapiens
95 XPO1 7514
Affinity Capture-MS Homo sapiens
96 USP15 9958
Co-fractionation Homo sapiens
97 EIF4G1 1981
Co-fractionation Homo sapiens
98 LAMP1 3916
Proximity Label-MS Homo sapiens
99 PRKAR2A 5576
Co-fractionation Homo sapiens
100 PRKCZ 5590
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
101 CUL3 8452
Affinity Capture-MS Homo sapiens
102 YWHAZ 7534
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
103 MAP2K5  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
104 FARP2 9855
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
105 ARHGEF16 27237
Affinity Capture-MS Homo sapiens
106 NACC1 112939
Two-hybrid Homo sapiens
107 PDPK1 5170
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
108 KBTBD7  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
109 RIPK4  
Affinity Capture-MS Homo sapiens
110 KPNA2 3838
Co-fractionation Homo sapiens
111 HNRNPCL2 440563
Affinity Capture-MS Homo sapiens
112 GAB1  
Affinity Capture-Western Homo sapiens
113 BIRC6 57448
Co-fractionation Homo sapiens
114 IL7R  
Affinity Capture-MS Homo sapiens
115 RAPGEF2 9693
Affinity Capture-MS Homo sapiens
116 PPP2R1A 5518
Co-fractionation Homo sapiens
117 RPA3 6119
Proximity Label-MS Homo sapiens
118 WWC1  
Affinity Capture-MS Homo sapiens
119 GNLY  
Affinity Capture-MS Homo sapiens
120 PSMC5 5705
Co-fractionation Homo sapiens
121 AMOT 154796
Proximity Label-MS Homo sapiens
122 MFN2 9927
Proximity Label-MS Homo sapiens
123 DDRGK1 65992
Affinity Capture-MS Homo sapiens
124 PCM1 5108
Two-hybrid Homo sapiens
125 HSPA9 3313
Co-fractionation Homo sapiens
126 ADRM1 11047
Co-fractionation Homo sapiens
127 CHUK 1147
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
128 EDDM3B  
Affinity Capture-MS Homo sapiens
129 GBAS 2631
Affinity Capture-MS Homo sapiens
130 TAF6 6878
Co-fractionation Homo sapiens
131 LLGL2 3993
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
132 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
133 STK24 8428
Co-fractionation Homo sapiens
134 TMEM208  
Affinity Capture-MS Homo sapiens
135 PDGFD 80310
Affinity Capture-MS Homo sapiens
136 BAD  
Reconstituted Complex Homo sapiens
137 CPSF6 11052
Co-fractionation Homo sapiens
138 TP53 7157
Affinity Capture-MS Homo sapiens
139 FABP4 2167
Two-hybrid Homo sapiens
140 PARD6G 84552
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
141 CDC37 11140
Affinity Capture-MS Homo sapiens
142 IKBKG 8517
Two-hybrid Homo sapiens
143 CASP8 841
Two-hybrid Homo sapiens
144 FGB 2244
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
145 SMURF1 57154
Biochemical Activity Homo sapiens
146 SQSTM1 8878
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
FRET Homo sapiens
Two-hybrid Homo sapiens
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Protein-peptide Homo sapiens
Co-fractionation Homo sapiens
147 RNH1 6050
Co-fractionation Homo sapiens
148 DCTN2 10540
Co-fractionation Homo sapiens
149 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
150 PNMA1 9240
Affinity Capture-MS Homo sapiens
151 HSP90AA1 3320
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
152 GNB1 2782
Co-fractionation Homo sapiens
153 FLII 2314
Co-fractionation Homo sapiens
154 TRIP12 9320
Co-fractionation Homo sapiens
155 NCAPD2 9918
Co-fractionation Homo sapiens
156 MAP1LC3A 84557
Affinity Capture-MS Homo sapiens
157 TRAPPC13 80006
Affinity Capture-MS Homo sapiens
158 GAPDH 2597
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
159 PSMA5 5686
Co-fractionation Homo sapiens
160 PARD6B 84612
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
161 B3GAT1  
Proximity Label-MS Homo sapiens
162 FRS2 10818
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
163 SMG1 23049
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
164 EPHA2 1969
Proximity Label-MS Homo sapiens
165 KERA  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
166 CD44 960
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
167 PPP1CB 5500
Co-fractionation Homo sapiens
168 Pard6b  
Affinity Capture-MS Mus musculus
169 PSMD1 5707
Co-fractionation Homo sapiens
170 PARD6A  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
171 IKBKB 3551
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
172 CAV1 857
Proximity Label-MS Homo sapiens
173 GREM2 64388
Affinity Capture-MS Homo sapiens
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Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here