Gene description for PLA2G2A
Gene name	phospholipase A2, group IIA (platelets, synovial fluid)
Gene symbol	PLA2G2A
Other names/aliases	MOM1 PLA2 PLA2B PLA2L PLA2S PLAS1 sPLA2
Species	Homo sapiens
Database cross references - PLA2G2A
ExoCarta	ExoCarta_5320
Vesiclepedia	VP_5320
Entrez Gene	5320
HGNC	9031
MIM	172411
UniProt	P14555
PLA2G2A identified in sEVs derived from the following tissue/cell type
Hepatocellular carcinoma cells	26054723

Gene ontology annotations for PLA2G2A

Molecular Function     phospholipase A2 activity GO:0004623 IDA     calcium ion binding GO:0005509 IBA     phospholipid binding GO:0005543 IBA     phospholipid binding GO:0005543 IDA     calcium-dependent phospholipase A2 activity GO:0047498 IBA     calcium-dependent phospholipase A2 activity GO:0047498 IDA     calcium-dependent phospholipase A2 activity GO:0047498 TAS     calcium-independent phospholipase A2 activity GO:0047499 IEA Biological Process     phospholipid metabolic process GO:0006644 IDA     inflammatory response GO:0006954 IEA     positive regulation of macrophage derived foam cell differentiation GO:0010744 TAS     lipid catabolic process GO:0016042 IEA     killing of cells of another organism GO:0031640 IEA     low-density lipoprotein particle remodeling GO:0034374 TAS     intestinal stem cell homeostasis GO:0036335 ISS     negative regulation of T cell proliferation GO:0042130 IBA     phosphatidylethanolamine metabolic process GO:0046337 IDA     phosphatidylcholine metabolic process GO:0046470 IBA     phosphatidylcholine metabolic process GO:0046470 IDA     phosphatidylglycerol metabolic process GO:0046471 IBA     phosphatidic acid metabolic process GO:0046473 IDA     arachidonate secretion GO:0050482 IEA     positive regulation of inflammatory response GO:0050729 TAS     defense response to Gram-positive bacterium GO:0050830 IMP     defense response to Gram-positive bacterium GO:0050830 TAS     positive regulation of ERK1 and ERK2 cascade GO:0070374 IDA     regulation of neutrophil activation GO:1902563 IDA Subcellular Localization     extracellular region GO:0005576 TAS     extracellular space GO:0005615 HDA     extracellular space GO:0005615 IDA     mitochondrial outer membrane GO:0005741 IEA     endoplasmic reticulum GO:0005783 IDA     endoplasmic reticulum membrane GO:0005789 TAS     plasma membrane GO:0005886 IEA     secretory granule GO:0030141 IEA     perinuclear region of cytoplasm GO:0048471 IEA     extracellular exosome GO:0070062 HDA