Gene description for Lamc1
Gene name
laminin, gamma 1
Gene symbol
Lamc1
Other names/aliases
Lamb2
Species
Mus musculus
Database cross references - Lamc1
ExoCarta
ExoCarta_226519
Vesiclepedia
VP_226519
Entrez Gene
226519
Lamc1 identified in sEVs derived from the following tissue/cell type
Colon cancer cells
37309723
Fibroblasts
23260141
T-cell lymphoma cells
37309723
Gene ontology annotations for Lamc1
Experiment description of studies that identified Lamc1 in sEVs
1
Experiment ID
907
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
37309723
Organism
Mus musculus
Experiment description
Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors
"Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name
Proteomics
Publication year
2023
Sample
Colon cancer cells
Sample name
C26
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
2
Experiment ID
210
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|FLOT1
Enriched markers
✘
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23260141
Organism
Mus musculus
Experiment description
Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors
"Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL."
Journal name
Cell
Publication year
2012
Sample
Fibroblasts
Sample name
Normal-Fibroblasts (L cells)
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
3
Experiment ID
908
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
37309723
Organism
Mus musculus
Experiment description
Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors
"Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name
Proteomics
Publication year
2023
Sample
T-cell lymphoma cells
Sample name
EL4
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
Protein-protein interactions for Lamc1
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
Lamc1
226519
Cross-Linking-MS (XL-MS)
Mus musculus
Cross-Linking-MS (XL-MS)
Mus musculus
2
Ntn4
Reconstituted Complex
Mus musculus
3
Eed
Affinity Capture-MS
Mus musculus
4
Lama1
Affinity Capture-Western
Mus musculus
5
Tufm
Cross-Linking-MS (XL-MS)
Mus musculus
6
Pou5f1
Affinity Capture-MS
Mus musculus
7
Lamb1
16777
Co-fractionation
Mus musculus
8
Hspb2
69253
Affinity Capture-MS
Mus musculus
9
Itgb4
Co-fractionation
Mus musculus
View the network
image/svg+xml
Pathways in which Lamc1 is involved
No pathways found