Experiment description of studies that identified SEZ6L2 in sEVs

1 Experiment ID 235 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH Enriched markers ✔ HSP90B1 Negative markers ✔ qNano Particle analysis Identified molecule mRNA Identification method RNA Sequencing PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N" Journal name Carcinogenesis Publication year 2015 Sample Hepatocellular carcinoma cells Sample name HKCI-8 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RT-PCR RNA Sequencing

Protein-protein interactions for SEZ6L2

Protein Interactor ExoCarta ID Identification method PubMed Species 1 UNG   Two-hybrid Homo sapiens 2 FCN1 2219 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 3 RAMP3   Affinity Capture-MS Homo sapiens 4 LGALS9 3965 Affinity Capture-MS Homo sapiens 5 PICK1   Affinity Capture-MS Homo sapiens 6 CD200R1 131450 Affinity Capture-MS Homo sapiens 7 OASL 8638 Two-hybrid Homo sapiens 8 SERPINA12   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 9 TK1 7083 Two-hybrid Homo sapiens 10 FAM19A1   Affinity Capture-MS Homo sapiens 11 MICA 100507436 Affinity Capture-MS Homo sapiens 12 FCGRT 2217 Affinity Capture-MS Homo sapiens 13 LGALS3 3958 Affinity Capture-MS Homo sapiens 14 CFC1   Affinity Capture-MS Homo sapiens 15 FAM19A4   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 16 FOXA1   Two-hybrid Homo sapiens 17 LGALS1 3956 Affinity Capture-MS Homo sapiens 18 CBLN4   Affinity Capture-MS Homo sapiens 19 TOX3   Two-hybrid Homo sapiens 20 B3GALT4   Affinity Capture-MS Homo sapiens 21 CST6   Affinity Capture-MS Homo sapiens 22 LRRN4CL 221091 Affinity Capture-MS Homo sapiens 23 IL1R2   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 24 SFTPC   Affinity Capture-MS Homo sapiens 25 VSIG4   Affinity Capture-MS Homo sapiens 26 SIRPD   Affinity Capture-MS Homo sapiens 27 ETV5   Two-hybrid Homo sapiens 28 SDF2L1 23753 Affinity Capture-MS Homo sapiens 29 FZD7 8324 Affinity Capture-MS Homo sapiens 30 FBXO2 26232 Affinity Capture-MS Homo sapiens 31 NTRK1 4914 Affinity Capture-MS Homo sapiens 32 NXPH2   Affinity Capture-MS Homo sapiens 33 ALDH3B1 221 Affinity Capture-MS Homo sapiens 34 CDHR4   Affinity Capture-MS Homo sapiens 35 LGALS8 3964 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 36 PRELP 5549 Affinity Capture-MS Homo sapiens 37 TMPRSS13   Affinity Capture-MS Homo sapiens View the network

Pathways in which SEZ6L2 is involved

No pathways found